Commit Graph

528 Commits (e6f66f2f3b1d5dc4aeb4f535ac21cb0522893405)

Author SHA1 Message Date
Heng Li e6f66f2f3b disabled download counts
seems not working any more
2017-10-24 14:40:08 -04:00
Heng Li 70735098e2 fixed a typo in README 2017-10-24 14:39:33 -04:00
Heng Li d4b5dfc297 r533: added --no-pairing
to prevent the use of any pairing information for paired-end reads.
2017-10-23 14:09:32 -04:00
Heng Li 5acd709524 updated the download link to v2.3 2017-10-23 13:43:31 -04:00
Heng Li 306e4541f8 Released minimap2-2.3 (r531) 2017-10-22 23:13:35 -04:00
Heng Li 1dd221ad82 a bit more on short read mapping
The tech note still needs improvement. Will do that after the release of v2.3.
2017-10-22 18:38:35 -04:00
Heng Li c6b6392b70 minor wording changes 2017-10-21 23:46:36 -04:00
Heng Li dc37aee881 minor wording changes 2017-10-21 23:38:05 -04:00
Heng Li 37e627aa98 note on long cigar in README 2017-10-21 22:28:06 -04:00
Heng Li beeb806829 r526: fixed a bug when HPC is in use
It happened when the query HPC minimizer is longer than the reference HPC
minimizer close to the beginning of a contig. We may get a negative coordinate,
which causes an assertion failure.
2017-10-21 19:54:04 -04:00
Heng Li be7f3c4ffe r525: fixed a bug in chaining; handle ovlp ends 2017-10-20 21:34:52 -04:00
Heng Li bd04372873 r524: reverted to bwa-mem end bonus
and reduced the cost of clipping when filtering by identity
2017-10-20 16:57:31 -04:00
Heng Li 15ed0712c2 r523: fixed a performance bug in ksw2_ll
Wont' affect accuracy.
2017-10-20 13:00:10 -04:00
Heng Li 55dcbefe87 updated text (unfinished) 2017-10-20 12:44:54 -04:00
Heng Li 8abba332ad replaced mapQ plot with sr roc
figure legend and text to be updated later
2017-10-19 23:43:17 -04:00
Heng Li 4683da2455 r520: added option -L to write long cigar to CG 2017-10-17 17:32:44 -04:00
Heng Li ffd953029f r519: fixed a severe bug that misses long alns 2017-10-17 15:52:36 -04:00
Heng Li 04cf4ebf5e r518: increased the default -K to 500M
This helps multi-thread performance for ultra-long reads.
2017-10-17 13:21:29 -04:00
Heng Li 25ffd72690 r517: replaced --print-2nd with --secondary 2017-10-17 11:41:56 -04:00
Heng Li aa2d9d4e1b r516: throw a warning if -N0 is used 2017-10-16 14:55:35 -04:00
Heng Li addb61bcb2 r515: more conservative hit exclusion
When a hit covers a long query subsequence that has not been covered by better
primary hits, this hit is more likely to become a new primary hit.
2017-10-16 13:58:01 -04:00
Heng Li b24c9c90c7 updated mappy and example.c 2017-10-16 11:15:07 -04:00
Heng Li adf6cd7f52 r513: merged pre- and post-cigar blen and mlen
This saves a bit memory and is cleaner.
2017-10-16 10:55:18 -04:00
Heng Li e6f525edaf r512: option to filter poorly aligned reads 2017-10-16 10:38:22 -04:00
Heng Li 858213d513 r511: fixed wrong primary sam record 2017-10-12 23:02:18 -04:00
Heng Li dea3b60918 r510: fixed an off-by-1 bug for unmapped mate 2017-10-12 17:31:13 -04:00
Heng Li 7c555f9b7e r508: use two I/O threads for mapping
-x sr applies this option by default
2017-10-12 14:56:01 -04:00
Heng Li 2801ed9b4b r507: -K not working as is intended (#36) 2017-10-12 14:16:05 -04:00
Heng Li 27025c70a7 added evaluation scripts to README 2017-10-12 12:55:10 -04:00
Heng Li 9bafbe4e70 added Getting help and cs 2017-10-12 12:40:52 -04:00
Heng Li ce06188203 r506: fixed a memory leak 2017-10-12 10:12:22 -04:00
Heng Li 9862a75cd3 r505: a bit code simplification 2017-10-11 21:54:32 -04:00
Heng Li 3073f4a758 r504: better heuristics to reduce excessive ext 2017-10-11 21:42:11 -04:00
Heng Li ba6ddda6b0 Merge pull request #35 from mcshane/sam_fix
fix sam output for some unmapped queries
2017-10-11 20:09:16 -04:00
Heng Li 9364bc64d7 r501: added end_bonus to extz2 2017-10-11 09:39:41 -04:00
Shane McCarthy 5498565157 fix sam output for some unmapped queries 2017-10-11 08:46:24 +01:00
Heng Li 65abdb8f3c r500: temporarily disabled region trunc
because it is causing other problems.
2017-10-11 00:16:04 -04:00
Heng Li 7345621759 r499: end bonus working; DP region needs improve! 2017-10-11 00:14:25 -04:00
Heng Li ca632f907b r498: fixed a bug when merging like "4I5I" 2017-10-10 21:22:37 -04:00
Heng Li 6c78a980b6 r497: the previous change not working at the ends 2017-10-10 17:32:28 -04:00
Heng Li c217eecdb7 r496: avoid DP extending into another chain
When deciding the region for DP, exclude regions in the adjacent chain
2017-10-10 17:25:12 -04:00
Heng Li 13b66aad4d r495: fix impropriate CIGAR
1. Not left aligned
2. In one case, 50M24D50M becomes 24D100M. The leading D needs to be removed.
3. Avoid identical hits after DP
2017-10-10 11:59:44 -04:00
Heng Li 46fa520db9 r494: simpler and better SR gap filling
Still one thing to do: left alignment
2017-10-09 22:02:30 -04:00
Heng Li 1e53610fb4 r493: reduced calling extd2 for ungapped aln
Still need to improve in case of 3I5M3D
2017-10-09 21:13:34 -04:00
Heng Li 9396d9e11b r452: typo in the last commit 2017-10-09 10:05:32 -04:00
Heng Li 198849a716 r491: an ambiguous base costs the same as gap ext 2017-10-09 09:59:42 -04:00
Heng Li 9fea4d16b3 r490: improved short-read extension heuristic
Now we find the best scoring ungapped seeded segment and then extend from it.
There is no gap filling for short reads.
2017-10-08 21:36:34 -04:00
Heng Li f9415628a8 r489: don't use approximate zdrop
it doesn't work well
2017-10-08 19:29:09 -04:00
Heng Li 61e56c941d r488: parameter to control max fragment length 2017-10-07 23:54:32 -04:00
Heng Li f150257a0d r487: demote "map10k"; improved README 2017-10-07 19:19:40 -04:00