Heng Li
d1050f4eaf
r748: optionally to use system getopt() ( #134 )
2018-03-19 11:18:26 -04:00
Heng Li
bdc615c1d4
r741: added --min-occ-floor to improve #107
2018-03-12 14:32:27 -04:00
Heng Li
eeb314edd6
Release minimap2-2.9 (r720)
2018-02-24 09:31:09 -05:00
Heng Li
83c57a9d98
r719: fixed bad memory access
2018-02-23 17:27:41 -05:00
Heng Li
24a4808826
r718: retrieve sequence from the index
2018-02-23 10:18:26 -05:00
Heng Li
8fc5f8dc90
r711: assign proper mapq to primary inversions
2018-02-15 14:34:59 -05:00
Heng Li
a0d62519c1
r710: fixed incorrect inversion coordinate ( #112 )
2018-02-15 14:23:42 -05:00
Heng Li
1372977a37
r708: implemented double Z-drop thresholds ( #112 )
...
When aligning long reads, we would prefer to align through low-quality
regions. This requires a large Z-drop threshold. However, to find small
inversions, we need to use a small Z-drop. This commit address this
conflict with two Z-drop thresholds. When Z-drop exceeds the smaller
threshold, we perform a local alignment to check if there is a potential
inversion. If there is one, we break the alignment; otherwise we break
the alignment only if Z-drop excess the larger threshold.
This commit also fixes a bug that reported wrong coordinates when the
inversion is on the forward strand (#112 ).
2018-02-15 10:50:49 -05:00
Heng Li
c0e0d5d84b
r707: bugfix for inversions on rev strand ( #112 )
2018-02-14 14:09:03 -05:00
Heng Li
b328795051
r706: don't segfault upon wrong FASTA/Q ( #111 )
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The lack of robustness cost me several hours to identify.
2018-02-13 10:00:22 -05:00
Heng Li
7ef5490884
r703: added --max-clip-ratio
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still testing the option
2018-02-12 13:29:18 -05:00
Heng Li
a8d476c6ad
r686: end seed trimming don't go over long join
2018-02-06 11:31:32 -05:00
Heng Li
29b4a1786c
r685: tune end seed filter again
2018-02-05 11:48:22 -05:00
Heng Li
dbf284b2d9
r684: separate end score from min_chain_score
2018-02-05 11:40:38 -05:00
Heng Li
35d3e064bf
r677: reduce the change of missing hits
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that are close to end of alignments. It is still possible to create examples
that fail the heuristic.
2018-02-02 10:35:33 -05:00
Heng Li
53ce317e59
Release minimap2-2.8 (r672)
2018-02-01 12:50:20 -05:00
Heng Li
da6947cfa3
r671: cleanup command line options
2018-01-31 13:59:52 -05:00
Heng Li
46d6349af4
r670: added PE support to mappy
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and minor code cleanup
2018-01-31 11:33:08 -05:00
Heng Li
12a5a5fa3c
r669: improved self chain extension ( #10 )
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This has not fully resolved #10 , only alleviated the issue.
2018-01-30 20:05:02 -05:00
Heng Li
43bfa6199d
r667: warn if one query file has fewer records #92
2018-01-28 17:36:21 -05:00
Heng Li
72b9b0e3b6
r666: report if >=3 query files in SR mode #92
2018-01-28 17:15:57 -05:00
Heng Li
d676a5314b
r664: use --heat-sort for sr by default
2018-01-26 12:25:42 -05:00
Heng Li
123bc1d91d
put option operations in another file
2018-01-26 08:38:37 -05:00
Heng Li
543fa12e68
r659: for C++ compatibility
2018-01-19 10:40:18 -05:00
Heng Li
af1a871270
r658: gives a warning if -N0 is used
2018-01-19 08:33:20 -05:00
Heng Li
2b71181a37
r657: check -p ( #96 )
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Well, in principle, every option should be checked. Will do when someone raise
issues...
2018-01-19 01:03:38 -05:00
Heng Li
33f8157961
r655: options to map to one strand of the ref #91
2018-01-16 10:34:30 -05:00
Heng Li
eecc06086f
Released minimap2-2.7 (r654)
2018-01-09 13:16:00 -05:00
Heng Li
dfea113f28
r653: the last change may write "N" wrongly
2018-01-08 11:33:53 -05:00
Heng Li
f5cfd439ee
r651: incorrectly treat introns as deletions
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This happened when the last operation during backtracking is an intron.
2018-01-07 19:42:50 -05:00
Heng Li
dc9e3dcf4a
r639: changed -O/-E validation
2017-12-30 20:39:29 -05:00
Heng Li
cc75c12905
r638: disabled scoring checking
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I haven't figured out the exact bounds...
2017-12-30 07:50:40 -05:00
Heng Li
e420b17496
r629: API to construct index from strings
2017-12-18 22:29:46 -05:00
Heng Li
ab345e600b
r626: function to check incorrect scoring system
2017-12-13 12:23:43 -05:00
Heng Li
d003a00d71
r625: HPC sketch still has one minor issue
2017-12-13 09:40:42 -05:00
Heng Li
eb819c29e8
Release minimap2-2.6 (r623)
2017-12-12 11:09:59 -05:00
Heng Li
fb630de40a
r622: fixed bug in sdust due to recent refactor
2017-12-11 15:32:28 -05:00
Heng Li
43960a8ca7
r621: --print-qname also shows kalloc status
2017-12-11 12:30:08 -05:00
Heng Li
f6608fe99c
r620: revamped thread-local memory management
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* Don't preallocate sdust_buf or minizer list. kalloc should be fast enough -
benchmarks needed to confirm.
* Fixed a memory leak caused by divergence estimate (post v2.5)
* Reset the kalloc buffer after mapping a long query. This reduces peak memory
when large chunks of memory are allocated, at the cost of performance, though.
2017-12-11 12:11:10 -05:00
Heng Li
98a6e52c06
r618: heuristics to avoid tiny terminal exons
2017-12-11 00:57:55 -05:00
Heng Li
824712a4ee
r617: removed some unused code
2017-12-10 17:54:50 -05:00
Heng Li
98a999fe44
r611: added pseudocount when est divergence
2017-12-08 12:57:57 -05:00
Heng Li
fec7bd713f
r610: warning if db sequence is 0-lengthed ( #69 )
2017-12-07 21:05:39 -05:00
Heng Li
2f693e8ca4
r609: bugfix - SDUST masking not working
2017-12-07 11:45:38 -05:00
Heng Li
704ff9f4c6
r607: estimate sequence divergence
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Currently using the simplest method. There may be a more accurate estimate.
2017-12-06 16:14:39 -05:00
Heng Li
68c63f2d68
r606: fixed a sketch bug for long 256bp k-mer
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sketch() writes {-1,-1} to the output array.
2017-12-06 16:13:29 -05:00
Heng Li
984f7846c0
r601: bugfix - a similar issue to r600
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This bug unsets the alignment score of suboptimal alignments.
2017-11-30 11:51:34 -05:00
Heng Li
af1d6afba9
r600: bugfix - missing secondary alignments ( #71 )
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This should very rarely happen to typical data, but has a higher chance in
artifactual data.
2017-11-30 11:34:10 -05:00
Heng Li
131cfc6938
r574: build index without sequences
2017-11-11 21:38:38 -05:00
Heng Li
2f463b1db0
r573: prepare to generalize index
2017-11-11 19:54:06 -05:00