Commit Graph

484 Commits (9396d9e11bab4f22e62a73832a96c1eb3d8ade62)

Author SHA1 Message Date
Heng Li 9396d9e11b r452: typo in the last commit 2017-10-09 10:05:32 -04:00
Heng Li 198849a716 r491: an ambiguous base costs the same as gap ext 2017-10-09 09:59:42 -04:00
Heng Li 9fea4d16b3 r490: improved short-read extension heuristic
Now we find the best scoring ungapped seeded segment and then extend from it.
There is no gap filling for short reads.
2017-10-08 21:36:34 -04:00
Heng Li f9415628a8 r489: don't use approximate zdrop
it doesn't work well
2017-10-08 19:29:09 -04:00
Heng Li 61e56c941d r488: parameter to control max fragment length 2017-10-07 23:54:32 -04:00
Heng Li f150257a0d r487: demote "map10k"; improved README 2017-10-07 19:19:40 -04:00
Heng Li bf2d4f7aec r486: treat "U" as "T" for RNA reads (#33) 2017-10-07 18:53:25 -04:00
Heng Li 47b86e765b minor wording changes 2017-10-06 15:34:20 -04:00
Heng Li 56acf6ee28 completed README rewrite 2017-10-06 14:26:02 -04:00
Heng Li 4f6244bd4a revamped README; not finished yet 2017-10-06 13:02:25 -04:00
Heng Li c6384ed2c8 r482: increased short-read bandwidth to 100
This has very minor effect on speed.
2017-10-06 10:20:32 -04:00
Heng Li 2833a9c255 150bp mason2 simulation 2017-10-06 09:46:59 -04:00
Heng Li de2fcc1bf3 updated the mappy 2017-10-05 17:10:07 -04:00
Heng Li e0baf1ad54 r479: a bit code cleanup 2017-10-05 16:15:14 -04:00
Heng Li f266092699 r478: simplied useless code, a tiny bit 2017-10-05 15:56:00 -04:00
Heng Li 9c5767f9ed r477: renamed multi_seg to frag_mode 2017-10-05 15:48:17 -04:00
Heng Li ae2adf04d4 r476: multi-file fragment mode working 2017-10-05 15:39:26 -04:00
Heng Li b839758335 r475: added --cs=none; updated manpage 2017-10-05 15:27:37 -04:00
Heng Li f4a5d3a692 r474: replaced -S and --cs-no-equal with --cs 2017-10-05 15:03:03 -04:00
Heng Li 3ff6eda3a4 r473: don't count introns into blen 2017-10-05 14:37:21 -04:00
Heng Li 1a90bc8603 r472: fixed a bug when printing MAPQ/CIGAR 2017-10-05 12:46:11 -04:00
Heng Li abf2a90363 r471: all SAM features implemented; more tests! 2017-10-05 12:37:30 -04:00
Heng Li 5ab99eb26e more accurate SAM flag 2017-10-05 10:59:38 -04:00
Heng Li 7cc4f6f965 r469: first step towards PE SAM 2017-10-05 10:38:09 -04:00
Heng Li 16e6e589a8 r468: replaced ^ with ~ in cs 2017-10-04 22:17:12 -04:00
Heng Li 9aba11769c r467: added : (equal length) and ^ (intron) ops 2017-10-04 21:55:37 -04:00
Heng Li 7d50e646dd r466: detect multi-part index more smartly
though it might not work in an extremely rare case: the end of a sequence ends
at X*16384 and it is the last sequence in a batch. This can be resolved by
never letting the kstream_t buffer empty.
2017-10-04 17:32:58 -04:00
Heng Li 1554149158 r465: apply option -x before other options 2017-10-04 13:52:28 -04:00
Heng Li 19c39e704f r464: fixed a bug in pairing, due to randomization 2017-10-04 13:37:40 -04:00
Heng Li 2581c44a21 r463: optionally disable secondary hits 2017-10-04 13:24:41 -04:00
Heng Li 5babf41a38 r462: SAM primary flag not properly set 2017-10-04 13:11:29 -04:00
Heng Li 2a1e738a94 r461: randomize repetitive hits 2017-10-04 13:05:18 -04:00
Heng Li cf55c84056 r460: added option --no-long-join 2017-10-04 12:08:44 -04:00
Heng Li 841763ec24 Merge branch 'master' into sr 2017-10-04 11:42:44 -04:00
Heng Li 95eb1dec36 r458: fixed wrong chr for inversion aln (#30) 2017-10-04 11:32:06 -04:00
Heng Li 0fd0f2aed1 r457: fixed a bug on parsing -f 2017-09-30 00:00:44 -04:00
Heng Li ee9b2773a8 r456: min chain score should >k-mer length
or chain_dp() wastes time on unnecessarily sorting chains with one k-mer.
2017-09-29 22:33:55 -04:00
Heng Li 340483821e r455: set max_occ on command line 2017-09-29 22:18:43 -04:00
Heng Li 04fb2c2ec0 r454: rechain with higher max_occ if no good chain 2017-09-29 19:24:32 -04:00
Heng Li 0d4ecd19ee r453: avoid duplicated strcmp() for ava 2017-09-28 15:52:05 -04:00
Heng Li 0c63325985 r452: fixed - -G not working with -x sr 2017-09-28 14:28:12 -04:00
Heng Li 2a554a92e9 r451: changed rep_len mapq heuristic 2017-09-28 14:23:14 -04:00
Heng Li 935a6e6064 r450: differentiate exact repeats via mapq 2017-09-27 23:51:05 -04:00
Heng Li a13691d00d eval script works with /[12] in SAM 2017-09-27 23:33:59 -04:00
Heng Li 8301222174 r448: fixed a bug when computing PE quality 2017-09-27 21:54:07 -04:00
Heng Li 9541052564 r447: paired-end mapping quality
not as good as I would hope...
2017-09-27 15:39:25 -04:00
Heng Li 7e0d70bfd3 r445: pair coordinate adjustment working
Next: mapq adjustment, which will be tricky...
2017-09-27 15:38:18 -04:00
Heng Li a349d85280 r444: changed the way orientation is specified
The old model doesn't work with RF or RR orientation. The new model only works
with paired-end reads. For >2 segments, only FF is supported.
2017-09-27 12:33:10 -04:00
Heng Li f611edf6f2 r443: don't filter small cm for split seg 2017-09-26 16:17:58 -04:00
Heng Li 1b1dd0cd57 r442: default max_gap to 200 in the sr mode 2017-09-26 13:31:01 -04:00