Heng Li
841763ec24
Merge branch 'master' into sr
2017-10-04 11:42:44 -04:00
Heng Li
95eb1dec36
r458: fixed wrong chr for inversion aln ( #30 )
2017-10-04 11:32:06 -04:00
Heng Li
0fd0f2aed1
r457: fixed a bug on parsing -f
2017-09-30 00:00:44 -04:00
Heng Li
ee9b2773a8
r456: min chain score should >k-mer length
...
or chain_dp() wastes time on unnecessarily sorting chains with one k-mer.
2017-09-29 22:33:55 -04:00
Heng Li
340483821e
r455: set max_occ on command line
2017-09-29 22:18:43 -04:00
Heng Li
04fb2c2ec0
r454: rechain with higher max_occ if no good chain
2017-09-29 19:24:32 -04:00
Heng Li
0d4ecd19ee
r453: avoid duplicated strcmp() for ava
2017-09-28 15:52:05 -04:00
Heng Li
0c63325985
r452: fixed - -G not working with -x sr
2017-09-28 14:28:12 -04:00
Heng Li
2a554a92e9
r451: changed rep_len mapq heuristic
2017-09-28 14:23:14 -04:00
Heng Li
935a6e6064
r450: differentiate exact repeats via mapq
2017-09-27 23:51:05 -04:00
Heng Li
a13691d00d
eval script works with /[12] in SAM
2017-09-27 23:33:59 -04:00
Heng Li
8301222174
r448: fixed a bug when computing PE quality
2017-09-27 21:54:07 -04:00
Heng Li
9541052564
r447: paired-end mapping quality
...
not as good as I would hope...
2017-09-27 15:39:25 -04:00
Heng Li
7e0d70bfd3
r445: pair coordinate adjustment working
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Next: mapq adjustment, which will be tricky...
2017-09-27 15:38:18 -04:00
Heng Li
a349d85280
r444: changed the way orientation is specified
...
The old model doesn't work with RF or RR orientation. The new model only works
with paired-end reads. For >2 segments, only FF is supported.
2017-09-27 12:33:10 -04:00
Heng Li
f611edf6f2
r443: don't filter small cm for split seg
2017-09-26 16:17:58 -04:00
Heng Li
1b1dd0cd57
r442: default max_gap to 200 in the sr mode
2017-09-26 13:31:01 -04:00
Heng Li
92ec8bd859
added the /1 or /2 suffix
2017-09-26 12:04:35 -04:00
Heng Li
55d1e4f638
r440: better chain filtering for PE reads
2017-09-26 11:03:36 -04:00
Heng Li
64c0ad6b35
r439: use splice-like chain gap cost between segs
...
This improves accuracy
2017-09-25 16:04:38 -04:00
Heng Li
9538c985aa
r438: fixed a rare case that leads to missing hits
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It is a bug in chaining.
2017-09-25 14:59:34 -04:00
Heng Li
8f25cfa36e
r437: fixed uninialized memory on rep_len
2017-09-25 14:22:45 -04:00
Heng Li
81008dd371
r436: working on short reads
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The result is mixed - lots of room for tuning
2017-09-25 14:06:29 -04:00
Heng Li
3bb66e1ed3
multi-seg working on toy examples
2017-09-25 13:42:04 -04:00
Heng Li
a742f10164
get multi-seg code ready; probably not working yet
2017-09-24 15:17:17 -04:00
Heng Li
f0951141a1
allow to read multiple files interleaved
2017-09-24 14:33:05 -04:00
Heng Li
84bbc47152
two arrays should be freed with kfree(0,)
...
though in the current code, they are strictly equivalent.
2017-09-23 10:43:22 -04:00
Heng Li
5400191097
get batch sequence reader ready for paired-end
2017-09-22 09:56:31 -04:00
Heng Li
ef84e8b4e7
Merge branch 'master' into sr
2017-09-20 23:56:06 -04:00
Heng Li
1c948e0d1d
added GMAP iso-seq numbers
2017-09-20 23:54:02 -04:00
Heng Li
997011458c
fixed uninitialized value due to last commit
2017-09-20 15:10:48 -04:00
Heng Li
19d8eca3a1
moved array shrinking into chain_dp()
2017-09-20 14:58:57 -04:00
Heng Li
9943e5fdd0
backup
2017-09-20 14:35:46 -04:00
Heng Li
5b39a1b34b
Merge branch 'master' into sr
2017-09-20 12:24:08 -04:00
Heng Li
e3b5802b2e
r424: reduce memory for long query seqs
2017-09-20 12:22:13 -04:00
Heng Li
03d6894517
backup
2017-09-20 11:47:46 -04:00
Heng Li
645db3350e
Merge branch 'master' into sr
2017-09-20 11:15:14 -04:00
Heng Li
75e6bbc9f6
r421: removed the MM_F_SPLICE_BOTH mode
...
In the default splice mode, minimap2 applies two rounds of spliced alignment:
first assuming GT-AG to be the splice signal across all splicing sites and then
assuming CT-AC to be the signal. This is the idea strategy.
In the MM_F_SPLICE_BOTH mode, minimap2 applies one round of spliced alignment,
assuming GT-AG and CT-AC to be the splice signals AT THE SAME TIME. This will
be faster but less accurate. I don't think anyone would like to run minimap2 in
this mode, so I am removing it for clarity.
2017-09-20 11:11:53 -04:00
Heng Li
7a9b4db874
replaced --approx-ext with --sr
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--sr disables Z-drop and may come with other heurstics
2017-09-20 10:51:18 -04:00
Heng Li
4979e66ff0
Merge branch 'master' into sr
2017-09-20 10:20:31 -04:00
Heng Li
a686461e83
added github downloads counts
2017-09-20 10:11:58 -04:00
Heng Li
fd14618e61
no effective changes
2017-09-20 10:11:05 -04:00
Heng Li
5caadc28b4
Merge branch 'master' into sr
2017-09-19 22:31:14 -04:00
Heng Li
56014ba3db
avoid assertion failure given 0-length reads
2017-09-19 22:30:32 -04:00
Heng Li
b99c22840f
r414: avoid assertion failure for 0-length reads
2017-09-19 22:21:27 -04:00
Heng Li
c04420698e
fixed an uninitialized value
2017-09-19 16:21:21 -04:00
Heng Li
fb1bcc0084
early exploration
2017-09-19 16:18:28 -04:00
Heng Li
11081c6c27
r411: refactored kalloc for clarity
...
The new version is closer to K&R's original implementation.
2017-09-18 19:49:15 -04:00
Heng Li
60485790b4
updated version number in README
2017-09-17 20:25:54 -04:00
Heng Li
ea5a0cd17d
Release minimap2-2.2 (r409)
2017-09-17 20:08:47 -04:00