added a new Makefile for simde

Makefile

@@ -1,40 +1,26 @@
 CFLAGS=		-g -Wall -O2 -Wc++-compat #-Wextra
 CPPFLAGS=	-DHAVE_KALLOC
 INCLUDES=
-OBJS=		kthread.o kalloc.o misc.o bseq.o sketch.o sdust.o options.o index.o chain.o align.o hit.o map.o format.o pe.o esterr.o splitidx.o 
+OBJS=		kthread.o kalloc.o misc.o bseq.o sketch.o sdust.o options.o index.o chain.o align.o hit.o map.o format.o pe.o esterr.o splitidx.o ksw2_ll_sse.o
 PROG=		minimap2
 PROG_EXTRA=	sdust minimap2-lite
 LIBS=		-lm -lz -lpthread
 
-
-ifeq ($(no_simd),) # if no_simd is not defined
 ifeq ($(arm_neon),) # if arm_neon is not defined
-	OBJS+=ksw2_ll_sse.o
 ifeq ($(sse2only),) # if sse2only is not defined
 	OBJS+=ksw2_extz2_sse41.o ksw2_extd2_sse41.o ksw2_exts2_sse41.o ksw2_extz2_sse2.o ksw2_extd2_sse2.o ksw2_exts2_sse2.o ksw2_dispatch.o
 else                # if sse2only is defined
 	OBJS+=ksw2_extz2_sse.o ksw2_extd2_sse.o ksw2_exts2_sse.o
 endif
 else				# if arm_neon is defined
-	OBJS+=ksw2_ll_neon.o ksw2_extz2_neon.o ksw2_extd2_neon.o ksw2_exts2_neon.o
+	OBJS+=ksw2_extz2_neon.o ksw2_extd2_neon.o ksw2_exts2_neon.o
-ifeq ($(simde),)	# arm_neon without SIMDe -> use sse2neon
+    INCLUDES+=-Isse2neon
-	INCLUDES+=-Isse2neon
-endif
 ifeq ($(aarch64),)	#if aarch64 is not defined
 	CFLAGS+=-D_FILE_OFFSET_BITS=64 -mfpu=neon -fsigned-char
 else				#if aarch64 is defined
 	CFLAGS+=-D_FILE_OFFSET_BITS=64 -fsigned-char
 endif
 endif
-else
-	OBJS+=ksw2_ll_nosimd.o ksw2_extz2_nosimd.o ksw2_extd2_nosimd.o ksw2_exts2_nosimd.o
-	simde=1			# no_simd can be used only with SIMDe
-endif
-
-ifneq ($(simde),) # if simde is defined
-	CFLAGS+=-DSIMDE_ENABLE_NATIVE_ALIASES -DUSE_SIMDE
-	INCLUDES+=-Ilib/simde
-endif
 
 ifneq ($(asan),)
 	CFLAGS+=-fsanitize=address
@@ -70,8 +56,10 @@ sdust:sdust.c kalloc.o kalloc.h kdq.h kvec.h kseq.h ketopt.h sdust.h
 
 # SSE-specific targets on x86/x86_64
 
+ifeq ($(arm_neon),)   # if arm_neon is defined, compile this target with the default setting (i.e. no -msse2)
 ksw2_ll_sse.o:ksw2_ll_sse.c ksw2.h kalloc.h
 		$(CC) -c $(CFLAGS) -msse2 $(CPPFLAGS) $(INCLUDES) $< -o $@
+endif
 
 ksw2_extz2_sse41.o:ksw2_extz2_sse.c ksw2.h kalloc.h
 		$(CC) -c $(CFLAGS) -msse4.1 $(CPPFLAGS) -DKSW_CPU_DISPATCH $(INCLUDES) $< -o $@
@@ -96,9 +84,6 @@ ksw2_dispatch.o:ksw2_dispatch.c ksw2.h
 
 # NEON-specific targets on ARM
 
-ksw2_ll_neon.o:ksw2_ll_sse.c ksw2.h kalloc.h
-		$(CC) -c $(CFLAGS) $(CPPFLAGS) $(INCLUDES) $< -o $@
-
 ksw2_extz2_neon.o:ksw2_extz2_sse.c ksw2.h kalloc.h
 		$(CC) -c $(CFLAGS) $(CPPFLAGS) -DKSW_SSE2_ONLY -D__SSE2__ $(INCLUDES) $< -o $@
 
@@ -108,20 +93,6 @@ ksw2_extd2_neon.o:ksw2_extd2_sse.c ksw2.h kalloc.h
 ksw2_exts2_neon.o:ksw2_exts2_sse.c ksw2.h kalloc.h
 		$(CC) -c $(CFLAGS) $(CPPFLAGS) -DKSW_SSE2_ONLY -D__SSE2__ $(INCLUDES) $< -o $@
 
-# no-SIMD version
-
-ksw2_ll_nosimd.o:ksw2_ll_sse.c ksw2.h kalloc.h
-		$(CC) -c $(CFLAGS) $(CPPFLAGS) -DSIMDE_NO_NATIVE $(INCLUDES) $< -o $@
-
-ksw2_extz2_nosimd.o:ksw2_extz2_sse.c ksw2.h kalloc.h
-		$(CC) -c $(CFLAGS) $(CPPFLAGS) -DKSW_SSE2_ONLY -D__SSE2__ -DSIMDE_NO_NATIVE $(INCLUDES) $< -o $@
-
-ksw2_extd2_nosimd.o:ksw2_extd2_sse.c ksw2.h kalloc.h
-		$(CC) -c $(CFLAGS) $(CPPFLAGS) -DKSW_SSE2_ONLY -D__SSE2__ -DSIMDE_NO_NATIVE $(INCLUDES) $< -o $@
-
-ksw2_exts2_nosimd.o:ksw2_exts2_sse.c ksw2.h kalloc.h
-		$(CC) -c $(CFLAGS) $(CPPFLAGS) -DKSW_SSE2_ONLY -D__SSE2__ -DSIMDE_NO_NATIVE $(INCLUDES) $< -o $@
-
 # other non-file targets
 
 clean:

Makefile.simde

@@ -0,0 +1,97 @@
+CFLAGS=		-g -Wall -O2 -Wc++-compat #-Wextra
+CPPFLAGS=	-DHAVE_KALLOC -DUSE_SIMDE -DSIMDE_ENABLE_NATIVE_ALIASES
+INCLUDES=	-Ilib/simde
+OBJS=		kthread.o kalloc.o misc.o bseq.o sketch.o sdust.o options.o index.o chain.o align.o hit.o map.o format.o pe.o esterr.o splitidx.o \
+			ksw2_extz2_simde.o ksw2_extd2_simde.o ksw2_exts2_simde.o ksw2_ll_simde.o
+PROG=		minimap2
+PROG_EXTRA=	sdust minimap2-lite
+LIBS=		-lm -lz -lpthread
+
+
+ifneq ($(arm_neon),) # if arm_neon is defined
+ifeq ($(aarch64),)   #if aarch64 is not defined
+	CFLAGS+=-D_FILE_OFFSET_BITS=64 -mfpu=neon -fsigned-char
+else                 #if aarch64 is defined
+	CFLAGS+=-D_FILE_OFFSET_BITS=64 -fsigned-char
+endif
+endif
+
+ifneq ($(asan),)
+	CFLAGS+=-fsanitize=address
+	LIBS+=-fsanitize=address
+endif
+
+ifneq ($(tsan),)
+	CFLAGS+=-fsanitize=thread
+	LIBS+=-fsanitize=thread
+endif
+
+.PHONY:all extra clean depend
+.SUFFIXES:.c .o
+
+.c.o:
+		$(CC) -c $(CFLAGS) $(CPPFLAGS) $(INCLUDES) $< -o $@
+
+all:$(PROG)
+
+extra:all $(PROG_EXTRA)
+
+minimap2:main.o libminimap2.a
+		$(CC) $(CFLAGS) main.o -o $@ -L. -lminimap2 $(LIBS)
+
+minimap2-lite:example.o libminimap2.a
+		$(CC) $(CFLAGS) $< -o $@ -L. -lminimap2 $(LIBS)
+
+libminimap2.a:$(OBJS)
+		$(AR) -csru $@ $(OBJS)
+
+sdust:sdust.c kalloc.o kalloc.h kdq.h kvec.h kseq.h ketopt.h sdust.h
+		$(CC) -D_SDUST_MAIN $(CFLAGS) $< kalloc.o -o $@ -lz
+
+ksw2_ll_simde.o:ksw2_ll_sse.c ksw2.h kalloc.h
+		$(CC) -c $(CFLAGS) -msse2 $(CPPFLAGS) $(INCLUDES) $< -o $@
+
+ksw2_extz2_simde.o:ksw2_extz2_sse.c ksw2.h kalloc.h
+		$(CC) -c $(CFLAGS) -msse4.1 $(CPPFLAGS) $(INCLUDES) $< -o $@
+
+ksw2_extd2_simde.o:ksw2_extd2_sse.c ksw2.h kalloc.h
+		$(CC) -c $(CFLAGS) -msse4.1 $(CPPFLAGS) $(INCLUDES) $< -o $@
+
+ksw2_exts2_simde.o:ksw2_exts2_sse.c ksw2.h kalloc.h
+		$(CC) -c $(CFLAGS) -msse4.1 $(CPPFLAGS) $(INCLUDES) $< -o $@
+
+# other non-file targets
+
+clean:
+		rm -fr gmon.out *.o a.out $(PROG) $(PROG_EXTRA) *~ *.a *.dSYM build dist mappy*.so mappy.c python/mappy.c mappy.egg*
+
+depend:
+		(LC_ALL=C; export LC_ALL; makedepend -Y -- $(CFLAGS) $(CPPFLAGS) -- *.c)
+
+# DO NOT DELETE
+
+align.o: minimap.h mmpriv.h bseq.h kseq.h ksw2.h kalloc.h
+bseq.o: bseq.h kvec.h kalloc.h kseq.h
+chain.o: minimap.h mmpriv.h bseq.h kseq.h kalloc.h
+esterr.o: mmpriv.h minimap.h bseq.h kseq.h
+example.o: minimap.h kseq.h
+format.o: kalloc.h mmpriv.h minimap.h bseq.h kseq.h
+hit.o: mmpriv.h minimap.h bseq.h kseq.h kalloc.h khash.h
+index.o: kthread.h bseq.h minimap.h mmpriv.h kseq.h kvec.h kalloc.h khash.h
+index.o: ksort.h
+kalloc.o: kalloc.h
+ksw2_extd2_sse.o: ksw2.h kalloc.h
+ksw2_exts2_sse.o: ksw2.h kalloc.h
+ksw2_extz2_sse.o: ksw2.h kalloc.h
+ksw2_ll_sse.o: ksw2.h kalloc.h
+kthread.o: kthread.h
+main.o: bseq.h minimap.h mmpriv.h kseq.h ketopt.h
+map.o: kthread.h kvec.h kalloc.h sdust.h mmpriv.h minimap.h bseq.h kseq.h
+map.o: khash.h ksort.h
+misc.o: mmpriv.h minimap.h bseq.h kseq.h ksort.h
+options.o: mmpriv.h minimap.h bseq.h kseq.h
+pe.o: mmpriv.h minimap.h bseq.h kseq.h kvec.h kalloc.h ksort.h
+sdust.o: kalloc.h kdq.h kvec.h sdust.h
+self-chain.o: minimap.h kseq.h
+sketch.o: kvec.h kalloc.h mmpriv.h minimap.h bseq.h kseq.h
+splitidx.o: mmpriv.h minimap.h bseq.h kseq.h

README.md

@@ -80,11 +80,14 @@ directory to compile. If you see compilation errors, try `make sse2only=1`
 to disable SSE4 code, which will make minimap2 slightly slower.
 
 Minimap2 also works with ARM CPUs supporting the NEON instruction sets. To
-compile for 32 bit ARM architectures (such as ARMv7), use `make arm_neon=1`. To compile for for 64 bit ARM architectures (such as ARMv8), use `make arm_neon=1 aarch64=1`.
+compile for 32 bit ARM architectures (such as ARMv7), use `make arm_neon=1`. To
+compile for for 64 bit ARM architectures (such as ARMv8), use `make arm_neon=1
+aarch64=1`.
 
-Minimap2 can use [SIMD Everywhere (SIMDe)](https://github.com/nemequ/simde) library for porting implementation
+Minimap2 can use [SIMD Everywhere (SIMDe)][simde] library for porting
-to the different SIMD instruction sets. To compile using SIMDe, use `make simde=1`. To compile for ARM CPUs, add `simde=1` to the commands given above.
+implementation to the different SIMD instruction sets. To compile using SIMDe,
-SIMDe also enables non-SIMD implementation using `make no_simd=1`.
+use `make -f Makefile.simde`. To compile for ARM CPUs, use `Makefile.simde`
+with the ARM related command lines given above.
 
 ### <a name="general"></a>General usage
 
@@ -380,3 +383,4 @@ mappy` or [from BioConda][mappyconda] via `conda install -c bioconda mappy`.
 [manpage]: https://lh3.github.io/minimap2/minimap2.html
 [manpage-cs]: https://lh3.github.io/minimap2/minimap2.html#10
 [doi]: https://doi.org/10.1093/bioinformatics/bty191
+[smide]: https://github.com/nemequ/simde