fixed typos
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@ -194,7 +194,7 @@ the results by~\citep{Jain2020.11.01.363887}. Minimap2 v2.22 is as good as
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Winnowmap2 now. Note that we were setting the Sniffles mapping quality
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Winnowmap2 now. Note that we were setting the Sniffles mapping quality
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threshold to 10 in consistent with the benchmarks above. If we used the
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threshold to 10 in consistent with the benchmarks above. If we used the
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default threshold 20, v2.22 would miss additional five SVs (accounting for
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default threshold 20, v2.22 would miss additional five SVs (accounting for
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0.5\% of simulated SVs). For four out of these missing five SVs, minimap2 v2.22
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0.5\% of simulated SVs). For four out of these five missing SVs, minimap2 v2.22
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mapped more variant reads than Winnowmap2. Sniffles did not call these SVs
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mapped more variant reads than Winnowmap2. Sniffles did not call these SVs
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because minimap2 tended to give them conservative mapping quality. It is worth
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because minimap2 tended to give them conservative mapping quality. It is worth
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noting that the simulation here only considers a simple scenario in evolution.
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noting that the simulation here only considers a simple scenario in evolution.
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@ -212,7 +212,7 @@ so did not report the numbers.
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Minimap2 spends most computing time on base alignment. As recent improvements
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Minimap2 spends most computing time on base alignment. As recent improvements
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in v2.22 incur little additional computing and do not change the base alignment
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in v2.22 incur little additional computing and do not change the base alignment
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algorithm, the new version has similar performance to older verions. It is
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algorithm, the new version has similar performance to older versions. It is
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consistently faster than Winnowmap2 by several times. Sometimes simple
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consistently faster than Winnowmap2 by several times. Sometimes simple
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heuristics can be as effective as more sophisticated yet slower solutions.
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heuristics can be as effective as more sophisticated yet slower solutions.
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