minor wording improvement
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@ -68,7 +68,7 @@ and the ability to produce detailed alignment.
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%\subsubsection{Chaining}
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An \emph{anchor} is a 3-tuple $(x,y,w)$, indicating interval $[x-w+1,x]$ on the
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reference matching interval $[y-w+1,y]$ on the query. Given a list of anchors
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sorted by the ending reference position $x$, let $f(i)$ be the maximal chaining
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sorted by ending reference position $x$, let $f(i)$ be the maximal chaining
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score up to the $i$-th anchor in the list. $f(i)$ can be calculated with
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dynamic programming (DP):
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\begin{equation}\label{eq:chain}
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@ -186,7 +186,7 @@ GraphMap~\citep{Sovic:2016aa},
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minialign~\citep{Suzuki:2016} and
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NGMLR~\citep{Sedlazeck169557}. We excluded rHAT~\citep{Liu:2016ab},
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LAMSA~\citep{Liu:2017aa} and Kart~\citep{Lin:2017aa} because they either
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crashed or produced malformatted output. In this evaluation, Minimap2 has a
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crashed or produced malformatted output. In this evaluation, Minimap2 has
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higher power to distinguish unique and repetitive hits, and achieves overall
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higher mapping accuracy (Fig.~\ref{fig:eval}a). It is still the most accurate
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even if we skip DP-based alignment (data not shown), suggesting chaining alone
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@ -219,9 +219,9 @@ banding~\citep{Suzuki130633} or incremental banding.
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In addition to reference-based read mapping, minimap2 inherits minimap's
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ability to search against huge multi-species databases and to find read
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overlaps. On a few test data sets, minimap2 appears to yield slightly better
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miniasm assembly. Minimap2 can also align long assemblies or closely related
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genomes, though more thorough evaluations are needed. Genome alignment is an
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intricate topic.
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miniasm assembly. Minimap2 can also align closely related genomes, though it
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would benefit from more thorough evaluations. Genome alignment is an intricate
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topic.
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\section*{Acknowledgements}
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We owe a debt of gratitude to Hajime Suzuki for releasing his masterpiece and
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@ -315,9 +315,9 @@ y_{rt}&=&\max\{0,y_{r-1,t}+u_{r-1,t}-z_{rt}+q\}-q-e\\
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\tilde{y}_{rt}&=&\max\{0,\tilde{y}_{r-1,t}+u_{r-1,t}-z_{rt}+\tilde{q}\}-\tilde{q}-\tilde{e}
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\end{array}\right.
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\end{equation*}
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In this formulation, cells with the same row index $r$ are independent of each
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other. This allows us to fully vectorize the computation of all cells on the
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same anti-diagonal in one inner loop.
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In this formulation, cells with the same diagonal index $r$ are independent of
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each other. This allows us to fully vectorize the computation of all cells on
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the same anti-diagonal in one inner loop.
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On the condition that $q+e<\tilde{q}+\tilde{e}$ and $e>\tilde{e}$, the boundary
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condition of this equation in the diagonal-anti-diagonal coordinate is
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