gatk-3.8/python/vcf_b36_to_hg18.py

44 lines
1.2 KiB
Python
Executable File

from farm_commands2 import *
import os
import sys
from optparse import OptionParser
from datetime import date
import glob
import operator
import faiReader
import math
import shutil
import string
def main():
global OPTIONS
usage = "usage: %prog [options] b36VCF hg18VCF"
parser = OptionParser(usage=usage)
parser.add_option("", "--dry", dest="dry",
action='store_true', default=False,
help="If provided, nothing actually gets run, just a dry run")
(OPTIONS, args) = parser.parse_args()
if len(args) != 2:
parser.error("incorrect number of arguments")
b36vcf, hg18vcf = args
temp = open("tmp", 'w')
mitotemp = open("mtmp",'w')
for line in open(b36vcf):
length = len(line)
if length > 2 and line[0] != '#':
if line[0:2] == 'MT':
spline = line.split("\t")
spline[0] = "chrM"
mitotemp.write("\t".join(spline))
line = 'chr' + line
temp.write(line)
out.close()
mitotemp.close()
os.system("cat mtmp tmp > "+hg18vcf+" ; rm mtmp ; rm tmp")
if __name__ == "__main__":
main()