Ryan Poplin e5cfdb4811 Bug fix for popular _Duplicate allele added to VariantContext_ error reported on the forum. It seems to be due to lower case bases in the reference being treated as reference mismatches. We would try to turn these mismatches into SNP events, for example c/C. We now uppercase the result from IndexedFastaSequenceFile.getSubsequenceAt()		2012-08-22 14:39:35 -04:00
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bqsr	Temporarily disabling multi-threaded usage of BaseRecalibrator for performance reasons.	2012-08-20 12:43:17 -04:00
compression/reducereads	Fixed divide by zero bug when downsampler goes over regions where reads are all filtered out. Added Guillermo's bug report as an integration test	2012-08-09 13:02:11 -04:00
genotyper	Fix for performance problem in GGA mode related to previous --regenotype commit. Instead of trying to hack around the determination of the calculation model when it's not needed, just simply overload the calculateGenotypes() method to add one that does simple genotyping. Re-enabling the Pool Caller integration tests.	2012-08-16 13:05:17 -04:00
haplotypecaller	Bug fix for popular _Duplicate allele added to VariantContext_ error reported on the forum. It seems to be due to lower case bases in the reference being treated as reference mismatches. We would try to turn these mismatches into SNP events, for example c/C. We now uppercase the result from IndexedFastaSequenceFile.getSubsequenceAt()	2012-08-22 14:39:35 -04:00