gatk-3.8/public
David Roazen e1cb5f6459 SnpEff annotator now assigns a functional class to each effect and distinguishes between actual effects and mere modifiers.
-We now assign a functional class (nonsense, missense, silent, or none) to each SnpEff effect, and add a
 SNPEFF_FUNCTIONAL_CLASS annotation to the INFO field of the output VCF.
-Effects are now prioritized according to both biological impact and functional class, instead of impact only.
-Many of SnpEff's "low-impact" effects are now classified as "modifiers" with lower priority than every
 other effect. This includes such "effects" as DOWNSTREAM, UPSTREAM, INTRON, GENE, EXON, and others that
 really describe the location of the variant rather than its biological effect.

This code will be short-lived (likely 1.2-only), as the next version of SnpEff will include most of these
features directly.

Checking this change into Stable+Unstable instead of Unstable because the current functional class stratification
in VariantEval is basically broken and urgently needs to be fixed for production purposes.
2011-09-23 16:06:52 -04:00
..
R Fixing units in queue job report Gantt plots 2011-09-12 09:01:34 -04:00
c Reinitialize random seed in the bwa bindings from the fixed seed stored in the 2011-07-22 13:41:53 -04:00
chainFiles Reorganized the codebase beneath top-level public and private directories, 2011-06-28 06:55:19 -04:00
doc Reorganized the codebase beneath top-level public and private directories, 2011-06-28 06:55:19 -04:00
java SnpEff annotator now assigns a functional class to each effect and distinguishes between actual effects and mere modifiers. 2011-09-23 16:06:52 -04:00
packages Fix the AnalayzeCovariates packaging. 2011-09-22 11:55:40 -04:00
perl Update to the bindings for liftOverVCF.pl (to -V from -B) 2011-09-15 15:33:09 -04:00
scala Fixed issue reported by chartl where cloned functions lost tags on @Inputs. 2011-09-16 12:46:07 -04:00
testdata GZIP VCF for testing 2011-08-19 09:05:39 -04:00