gatk-3.8/scala/qscript
kshakir 6c6e52def9 Renamed FCP to HybridSelectionPipeline.
Reviewed pipelines with dev team.
HSP updates:
- Calling SNPs and Indels at the same time then using SelectVariants to separate them for filtering
- Moved logs next to the files like in WGP
- Flattened outputs into one directory
- The file names for the final outputs are now <projectName>.vcf and <projectName>.eval
- Updated test to pass the chr20 intervals instead of a boolean
- Removed MultiFCP
WGP updates:
- Only cleaning and calling chromosomes 1-22, X, Y, MT
- Splitting SNPs from indels, filtering indels, then merging the selected SNPs and selected Indels back together to make sure there are no collisions in CombineVariants
- Still running VQSR on the recombined SNPs plus hard filtered indels
- Using hard indel filters from delangel
- Reduced number of tranches with rpoplin
- Changed prior for dbsnp from 10 to 8 with rpoplin
- Assuming identical samples on both CombineVariants
- Explicitly using variant merge option UNION even though it's the default
- Not setting the default genotype merge option PRIORITIZE
- Generating a vcf and eval for each tranche


git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5825 348d0f76-0448-11de-a6fe-93d51630548a
2011-05-19 22:47:02 +00:00
..
core trio WGS was creating trio WEX filenames. 2011-05-19 17:45:45 +00:00
examples When /etc/mailname is unreadable fall back to the hostname. 2011-04-11 20:22:44 +00:00
lib Thanks to mark: VCFInfoToTable removed in favor of a more flexible walker. Slight change to the argument structure of the walker to make it play more nicely with Queue: the field list parsing is pushed into the command line system (e.g. the variable is exposed as a List<String> and not a String, so Queue doesn't have to join a list into a string only to have it broken out again. This also allows the user to specify -F field1 -F field2 -F field3 if he/she so desires. 2010-12-15 03:33:36 +00:00
oneoffs Added VQSR to the downsampling script and changed memory limits for the clean script. 2011-05-18 20:07:42 +00:00
playground Renamed FCP to HybridSelectionPipeline. 2011-05-19 22:47:02 +00:00