gatk-3.8/java/test/org/broadinstitute/sting/gatk
delangel d534241f35 Major revamp of annotations for indels:
a) All rank sum tests now work for indels including multiallelic sites. For the latter cases, rank sum test is REF vs most common allele
b) Redid computation of HaplotypeScore for indels. It's now trivially easy to do because we are already computing likelihoods of each read vs haplotypes in GL computation so we reuse that if available. For multiallelic case, we score against N haplotypes where N is total called alleles.

Drawback is that all cases need information contained in likelihood table that stores likelihood for each pileup element, for each allele. If this table is not available we dont annotate, so we can only fully annotate indels right now when running UG but not when running VariantAnnotator alone.
 


git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5947 348d0f76-0448-11de-a6fe-93d51630548a
2011-06-04 15:34:24 +00:00
..
arguments A significant refactoring of the ROD system, done largely to simplify the process of 2010-12-31 04:52:22 +00:00
contexts/variantcontext Change md5 because conversion of a tri-allelic dbsnp indel record is now legit 2011-06-04 11:24:16 +00:00
datasources Contracts for GenomeLocParser and GenomeLoc are now fully implemented. 2011-05-21 02:01:59 +00:00
executive Changing testing framework from junit -> testng, for its enhanced configurability. 2010-11-01 21:31:44 +00:00
filters Convert GenomeLocParser into an instance variable. This change is required 2010-11-10 17:59:50 +00:00
iterators Some refactoring that Mauricio and I worked through together. Changed filters 2011-05-04 19:29:08 +00:00
refdata PLEASE READ ME! In order to prepare for the upcoming changes to VCF4, we felt it was best to split up the vcf3 and vcf4 codecs (vcf4 is not backwards compatible to vcf3 and certain changes are too complex to handle in both codecs). Using the 'VCF' rod type in the GATK will now throw a UserException for vcf3.2 or vcf3.3 files telling you to use the 'VCF3' type instead (and vice versa). Integration/unit tests have been updated. For programmers: note that there is currently a lot of code duplication in the two codecs (although I pulled out the easy stuff to a VCFCodecUtils class); however WE ARE FREEZING THE VCF3 CODEC AND WILL NO LONGER MAKE CHANGES TO IT. All updates/improvements will be targetted to the vcf4 codec only as vcf3 is there only to be able to read legacy files. People should really be using vcf4 files only. 2011-05-11 12:07:44 +00:00
report Added a utility method to retrieve the contig lengths for WG chunking. 2011-04-20 19:22:21 +00:00
traversals Fix requested by Lee Lichtenstein: first check to see whether it's time for 2011-04-20 03:22:48 +00:00
walkers Major revamp of annotations for indels: 2011-06-04 15:34:24 +00:00
GenomeAnalysisEngineUnitTest.java Contracts for GenomeLocParser and GenomeLoc are now fully implemented. 2011-05-21 02:01:59 +00:00
WalkerManagerUnitTest.java Changing testing framework from junit -> testng, for its enhanced configurability. 2010-11-01 21:31:44 +00:00