gatk-3.8/public/java/src/org/broadinstitute/sting/gatk/WalkerManager.java

429 lines
18 KiB
Java
Executable File

/*
* Copyright (c) 2010 The Broad Institute
*
* Permission is hereby granted, free of charge, to any person
* obtaining a copy of this software and associated documentation
* files (the "Software"), to deal in the Software without
* restriction, including without limitation the rights to use,
* copy, modify, merge, publish, distribute, sublicense, and/or sell
* copies of the Software, and to permit persons to whom the
* Software is furnished to do so, subject to the following
* conditions:
*
* The above copyright notice and this permission notice shall be
* included in all copies or substantial portions of the Software.
*
* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
* EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES
* OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
* NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT
* HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY,
* WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
* FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR
* THE USE OR OTHER DEALINGS IN THE SOFTWARE.
*/
package org.broadinstitute.sting.gatk;
import org.broadinstitute.sting.commandline.Hidden;
import org.broadinstitute.sting.gatk.datasources.rmd.ReferenceOrderedDataSource;
import org.broadinstitute.sting.gatk.filters.FilterManager;
import org.broadinstitute.sting.gatk.filters.ReadFilter;
import org.broadinstitute.sting.gatk.walkers.*;
import org.broadinstitute.sting.utils.baq.BAQ;
import org.broadinstitute.sting.utils.classloader.PluginManager;
import org.broadinstitute.sting.utils.exceptions.ReviewedStingException;
import org.broadinstitute.sting.utils.help.ResourceBundleExtractorDoclet;
import org.broadinstitute.sting.utils.text.TextFormattingUtils;
import java.util.*;
/**
* Plugin manager that also provides various utilities for inspecting Walkers.
*/
public class WalkerManager extends PluginManager<Walker> {
/**
* A collection of help text for walkers and their enclosing packages.
*/
private ResourceBundle helpText;
public WalkerManager() {
super(Walker.class,"walker","");
helpText = TextFormattingUtils.loadResourceBundle("StingText");
}
/**
* Get the list of walkers currently available to the GATK, organized
* by package.
* @param visibleWalkersOnly If true, return only the walker names that aren't hidden.
* @return Names of currently available walkers.
*/
public Map<String,Collection<Class<? extends Walker>>> getWalkerNamesByPackage(boolean visibleWalkersOnly) {
Map<String,Collection<Class<? extends Walker>>> walkersByPackage = new HashMap<String,Collection<Class<? extends Walker>>>();
for(Class<? extends Walker> walker: getPlugins()) {
if(visibleWalkersOnly && isHidden(walker))
continue;
// Extract the name for the package; if the walker is in the unnamed package, use the empty string
String walkerPackage = walker.getPackage() != null ? walker.getPackage().getName() : "";
if(!walkersByPackage.containsKey(walkerPackage))
walkersByPackage.put(walkerPackage,new ArrayList<Class<? extends Walker>>());
walkersByPackage.get(walkerPackage).add(walker);
}
return Collections.unmodifiableMap(walkersByPackage);
}
/**
* Gets the display name for a given package.
* @param packageName Fully qualified package name.
* @return A suitable display name for the package.
*/
public String getPackageDisplayName(String packageName) {
// ...try to compute the override from the text of the package name, while accounting for
// unpackaged walkers.
String displayName = packageName.substring(packageName.lastIndexOf('.')+1);
if (displayName.trim().equals("")) displayName = "<unpackaged>";
return displayName;
}
/**
* Gets the help text associated with a given package name.
* @param packageName Package for which to search for help text.
* @return Package help text, or "" if none exists.
*/
public String getPackageSummaryText(String packageName) {
String key = String.format("%s.%s",packageName, ResourceBundleExtractorDoclet.SUMMARY_TAGLET_NAME);
if(!helpText.containsKey(key))
return "";
return helpText.getString(key);
}
/**
* Gets the summary help text associated with a given walker type.
* @param walkerType Type of walker for which to search for help text.
* @return Walker summary description, or "" if none exists.
*/
public String getWalkerSummaryText(Class<? extends Walker> walkerType) {
String walkerSummary = String.format("%s.%s",walkerType.getName(), ResourceBundleExtractorDoclet.SUMMARY_TAGLET_NAME);
if(!helpText.containsKey(walkerSummary))
return "";
return helpText.getString(walkerSummary);
}
/**
* Gets the summary help text associated with a given walker type.
* @param walker Walker for which to search for help text.
* @return Walker summary description, or "" if none exists.
*/
public String getWalkerSummaryText(Walker walker) {
return getWalkerSummaryText(walker.getClass());
}
/**
* Gets the descriptive help text associated with a given walker type.
* @param walkerType Type of walker for which to search for help text.
* @return Walker full description, or "" if none exists.
*/
public String getWalkerDescriptionText(Class<? extends Walker> walkerType) {
String walkerDescription = String.format("%s.%s",walkerType.getName(), ResourceBundleExtractorDoclet.DESCRIPTION_TAGLET_NAME);
if(!helpText.containsKey(walkerDescription))
return "";
return helpText.getString(walkerDescription);
}
/**
* Gets the descriptive help text associated with a given walker type.
* @param walker Walker for which to search for help text.
* @return Walker full description, or "" if none exists.
*/
public String getWalkerDescriptionText(Walker walker) {
return getWalkerDescriptionText(walker.getClass());
}
/**
* Retrieves the walker class given a walker name.
* @param walkerName Name of the walker.
* @return Class representing the walker.
*/
public Class<? extends Walker> getWalkerClassByName(String walkerName) {
return getPluginsByName().get(walkerName);
}
/**
* Gets the data source for the provided walker.
* @param walkerClass The class of the walker.
* @return Which type of data source to traverse over...reads or reference?
*/
public static DataSource getWalkerDataSource(Class<? extends Walker> walkerClass) {
By byDataSource = walkerClass.getAnnotation(By.class);
if( byDataSource == null )
throw new ReviewedStingException("Unable to find By annotation for walker class " + walkerClass.getName());
return byDataSource.value();
}
/**
* Gets the data source for the provided walker.
* @param walker The walker.
* @return Which type of data source to traverse over...reads or reference?
*/
public static DataSource getWalkerDataSource(Walker walker) {
return getWalkerDataSource(walker.getClass());
}
/**
* Get a list of RODs allowed by the walker.
* @param walkerClass Class of the walker to query.
* @return The list of allowed reference meta data.
*/
public static List<RMD> getAllowsMetaData(Class<? extends Walker> walkerClass) {
return Collections.<RMD>emptyList();
}
/**
* Determine whether the given walker supports the given data source.
* @param walkerClass Class of the walker to query.
* @param dataSource Source to check for .
* @return True if the walker forbids this data type. False otherwise.
*/
public static boolean isAllowed(Class<? extends Walker> walkerClass, DataSource dataSource) {
Allows allowsDataSource = getWalkerAllowed(walkerClass);
// Allows is less restrictive than requires. If an allows
// clause is not specified, any kind of data is allowed.
if( allowsDataSource == null )
return true;
return Arrays.asList(allowsDataSource.value()).contains(dataSource);
}
/**
* Determine whether the given walker supports the given data source.
* @param walker Walker to query.
* @param dataSource Source to check for .
* @return True if the walker forbids this data type. False otherwise.
*/
public static boolean isAllowed(Walker walker, DataSource dataSource) {
return isAllowed(walker.getClass(), dataSource);
}
/**
* Determine whether the given walker supports the given reference ordered data.
* @param walkerClass Class of the walker to query.
* @param rod Source to check.
* @return True if the walker forbids this data type. False otherwise.
*/
public static boolean isAllowed(Class<? extends Walker> walkerClass, ReferenceOrderedDataSource rod) {
return true;
}
/**
* Determine whether the given walker supports the given reference ordered data.
* @param walker Walker to query.
* @param rod Source to check.
* @return True if the walker forbids this data type. False otherwise.
*/
public static boolean isAllowed(Walker walker, ReferenceOrderedDataSource rod) {
return isAllowed(walker.getClass(), rod);
}
/**
* Determine whether the given walker requires the given data source.
* @param walkerClass Class of the walker to query.
* @param dataSource Source to check for.
* @return True if the walker allows this data type. False otherwise.
*/
public static boolean isRequired(Class<? extends Walker> walkerClass, DataSource dataSource) {
Requires requiresDataSource = getWalkerRequirements(walkerClass);
return Arrays.asList(requiresDataSource.value()).contains(dataSource);
}
/**
* Determine whether the given walker requires the given data source.
* @param walker Walker to query.
* @param dataSource Source to check for.
* @return True if the walker allows this data type. False otherwise.
*/
public static boolean isRequired(Walker walker, DataSource dataSource) {
return isRequired(walker.getClass(), dataSource);
}
/**
* Get a list of RODs required by the walker.
* @param walkerClass Class of the walker to query.
* @return The list of required reference meta data.
*/
public static List<RMD> getRequiredMetaData(Class<? extends Walker> walkerClass) {
return Collections.emptyList();
}
/**
* Get a list of RODs required by the walker.
* @param walker Walker to query.
* @return The list of required reference meta data.
*/
public static List<RMD> getRequiredMetaData(Walker walker) {
return getRequiredMetaData(walker.getClass());
}
/**
* Reports whether this walker type is hidden -- in other words, whether it'll appear in the help output.
* @param walkerType Class to test for visibility.
* @return True if the walker should be hidden. False otherwise.
*/
public static boolean isHidden(Class<? extends Walker> walkerType) {
return walkerType.isAnnotationPresent(Hidden.class);
}
/**
* Extracts filters that the walker has requested be run on the dataset.
* @param walkerClass Class of the walker to inspect for filtering requests.
* @param filterManager Manages the creation of filters.
* @return A non-empty list of filters to apply to the reads.
*/
public static List<ReadFilter> getReadFilters(Class<? extends Walker> walkerClass, FilterManager filterManager) {
List<ReadFilter> filters = new ArrayList<ReadFilter>();
for(Class<? extends ReadFilter> filterType: getReadFilterTypes(walkerClass))
filters.add(filterManager.createFilterByType(filterType));
return filters;
}
/**
* Extracts filters that the walker has requested be run on the dataset.
* @param walker Walker to inspect for filtering requests.
* @param filterManager Manages the creation of filters.
* @return A non-empty list of filters to apply to the reads.
*/
public static List<ReadFilter> getReadFilters(Walker walker, FilterManager filterManager) {
return getReadFilters(walker.getClass(), filterManager);
}
/**
* Gets the type of downsampling method requested by the walker. If an alternative
* downsampling method is specified on the command-line, the command-line version will
* be used instead.
* @param walkerClass The class of the walker to interrogate.
* @return The downsampling method, as specified by the walker. Null if none exists.
*/
public static DownsamplingMethod getDownsamplingMethod(Class<? extends Walker> walkerClass) {
DownsamplingMethod downsamplingMethod = null;
if( walkerClass.isAnnotationPresent(Downsample.class) ) {
Downsample downsampleParameters = walkerClass.getAnnotation(Downsample.class);
DownsampleType type = downsampleParameters.by();
Integer toCoverage = downsampleParameters.toCoverage() >= 0 ? downsampleParameters.toCoverage() : null;
Double toFraction = downsampleParameters.toFraction() >= 0.0d ? downsampleParameters.toFraction() : null;
downsamplingMethod = new DownsamplingMethod(type,toCoverage,toFraction);
}
return downsamplingMethod;
}
public static BAQ.QualityMode getBAQQualityMode(Walker walker) {
return walker.getClass().getAnnotation(BAQMode.class).QualityMode();
}
public static BAQ.ApplicationTime getBAQApplicationTime(Walker walker) {
return walker.getClass().getAnnotation(BAQMode.class).ApplicationTime();
}
/**
* Gets the type of downsampling method requested by the walker. If an alternative
* downsampling method is specified on the command-line, the command-line version will
* be used instead.
* @param walker The walker to interrogate.
* @return The downsampling method, as specified by the walker. Null if none exists.
*/
public static DownsamplingMethod getDownsamplingMethod(Walker walker) {
return getDownsamplingMethod(walker.getClass());
}
/**
* Create a name for this type of walker.
*
* @param walkerType The type of walker.
* @return A name for this type of walker.
*/
@Override
public String getName(Class<? extends Walker> walkerType) {
String walkerName = "";
if (walkerType.getAnnotation(WalkerName.class) != null)
walkerName = walkerType.getAnnotation(WalkerName.class).value().trim();
else
walkerName = super.getName(walkerType);
return walkerName;
}
/**
* Utility to get the requires attribute from the walker.
* Throws an exception if requirements are missing.
* @param walkerClass Class of the walker to query for required data.
* @return Required data attribute.
*/
private static Requires getWalkerRequirements(Class<? extends Walker> walkerClass) {
Requires requiresDataSource = walkerClass.getAnnotation(Requires.class);
if( requiresDataSource == null )
throw new ReviewedStingException( "Unable to find data types required by walker class " + walkerClass.getName());
return requiresDataSource;
}
/**
* Utility to get the requires attribute from the walker.
* Throws an exception if requirements are missing.
* @param walker Walker to query for required data.
* @return Required data attribute.
*/
private static Requires getWalkerRequirements(Walker walker) {
return getWalkerRequirements(walker.getClass());
}
/**
* Utility to get the forbidden attribute from the walker.
* @param walkerClass Class of the walker to query for required data.
* @return Required data attribute. Null if forbidden info isn't present.
*/
private static Allows getWalkerAllowed(Class<? extends Walker> walkerClass) {
Allows allowsDataSource = walkerClass.getAnnotation(Allows.class);
return allowsDataSource;
}
/**
* Utility to get the forbidden attribute from the walker.
* @param walker Walker to query for required data.
* @return Required data attribute. Null if forbidden info isn't present.
*/
private static Allows getWalkerAllowed(Walker walker) {
return getWalkerAllowed(walker.getClass());
}
/**
* Gets the list of filtering classes specified as walker annotations.
* @param walkerClass Class of the walker to inspect.
* @return An array of types extending from SamRecordFilter. Will never be null.
*/
public static Collection<Class<? extends ReadFilter>> getReadFilterTypes(Class<?> walkerClass) {
List<Class<? extends ReadFilter>> filterTypes = new ArrayList<Class<? extends ReadFilter>>();
while(walkerClass != null) {
if(walkerClass.isAnnotationPresent(ReadFilters.class)) {
for ( Class c : walkerClass.getAnnotation(ReadFilters.class).value() ) {
if( !filterTypes.contains(c) )
filterTypes.add(c);
}
}
walkerClass = walkerClass.getSuperclass();
}
return filterTypes;
}
/**
* Gets the list of filtering classes specified as walker annotations.
* @param walker The walker to inspect.
* @return An array of types extending from SamRecordFilter. Will never be null.
*/
public static Collection<Class<? extends ReadFilter>> getReadFilterTypes(Walker walker) {
return getReadFilterTypes(walker.getClass());
}
}