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a647f1e076
gatk-3.8
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Ryan Poplin
a647f1e076
Refactoring the PairHMM util class to allow for multiple implementations which can be specified by the callers via an enum argument. Adding an optimized PairHMM implementation which caches per-read calculations as well as a logless implementation which drastically reduces the runtime of the HMM while also increasing the precision of the result. In the HaplotypeCaller we now lexicographically sort the haplotypes to take maximal benefit of the haplotype offset optimization which only recalculates the HMM matrices after the first differing base in the haplotype. Many thanks to Mauricio for all the initial groundwork for these optimizations. The change to the one HC integration test is in the fourth decimal of HaplotypeScore.
2012-10-20 16:38:18 -04:00
..
R
Fix a nasty bug in reading GATK reports with a single line
2012-09-10 20:14:13 -04:00
c
At chartl's request, add the bwa aln -N and bwa aln -m parameters to the bindings.
2012-01-17 14:47:53 -05:00
chainFiles
Reorganized the codebase beneath top-level public and private directories,
2011-06-28 06:55:19 -04:00
doc
Reorganized the codebase beneath top-level public and private directories,
2011-06-28 06:55:19 -04:00
java
Refactoring the PairHMM util class to allow for multiple implementations which can be specified by the callers via an enum argument. Adding an optimized PairHMM implementation which caches per-read calculations as well as a logless implementation which drastically reduces the runtime of the HMM while also increasing the precision of the result. In the HaplotypeCaller we now lexicographically sort the haplotypes to take maximal benefit of the haplotype offset optimization which only recalculates the HMM matrices after the first differing base in the haplotype. Many thanks to Mauricio for all the initial groundwork for these optimizations. The change to the one HC integration test is in the fourth decimal of HaplotypeScore.
2012-10-20 16:38:18 -04:00
keys
Public-key authorization scheme to restrict use of NO_ET
2012-03-06 00:09:43 -05:00
packages
Removed 'Walker' suffix from packages/GATKEngine.xml that were breaking the packaged release.
2012-07-23 16:32:31 -04:00
perl
Split out contig names from Reference .fai file on white space (to support the GATK resource bundle's file human_g1k_v37.fasta.fai.gz, which does not use tab delimiters)
2012-06-07 16:56:32 -04:00
scala
Added explicit @ClassType annotations to @Argument for Option[Int] or Option[Double] since scala seems to change the reflected type to Option[Object] on some systems.
2012-10-19 13:20:29 -04:00
testdata
Reverting move of BQSR tests to public, as per DR's email
2012-07-19 10:02:05 -04:00