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76a95fdedf
gatk-3.8
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Guillermo del Angel
76a95fdedf
Full implementation of multiallelic exact model for pools. Still super-linear so not useable at scale but it should be a gold standard to compare to. Unit tests are not exhaustive yet, will be expanded to provide better test coverage. Small inconsequential optimization in MathUtils: we're already caching log10(factorial(n)) for large n, so might as well use the cached values to compute binomial and multinomial coefficients instead of the log-gamma approximation which is more expensive (doesn't seem to save much time either in PoolCaller nor in UG though).
2012-05-02 09:24:28 -04:00
..
R
Add warning message about ratios in variantQCreport, give ratio for MAF > 10%
2012-04-25 12:22:32 -04:00
c
At chartl's request, add the bwa aln -N and bwa aln -m parameters to the bindings.
2012-01-17 14:47:53 -05:00
chainFiles
Reorganized the codebase beneath top-level public and private directories,
2011-06-28 06:55:19 -04:00
doc
Reorganized the codebase beneath top-level public and private directories,
2011-06-28 06:55:19 -04:00
java
Full implementation of multiallelic exact model for pools. Still super-linear so not useable at scale but it should be a gold standard to compare to. Unit tests are not exhaustive yet, will be expanded to provide better test coverage. Small inconsequential optimization in MathUtils: we're already caching log10(factorial(n)) for large n, so might as well use the cached values to compute binomial and multinomial coefficients instead of the log-gamma approximation which is more expensive (doesn't seem to save much time either in PoolCaller nor in UG though).
2012-05-02 09:24:28 -04:00
keys
Public-key authorization scheme to restrict use of NO_ET
2012-03-06 00:09:43 -05:00
packages
Remove unnecessary and obscure usage of old R
2012-05-01 13:39:09 -04:00
perl
Update to the bindings for liftOverVCF.pl (to -V from -B)
2011-09-15 15:33:09 -04:00
scala
Refactoring/fixing up UG HMM code: a) Make code use PairHMM class instead of having duplicated code. That way UG and HaplotypeCaller now use same core code. Changes to be able to do this: 1. Compute context-dependent GOP as a function of read, not of haplotype, b) Extracted code to initialize HMM arrays into separate method, c) Move PairHMM class and unit test to public, d) Reenable banded code in PairHMM, inverted sense of flag (true=enable feature) but leave off in HaplotypeCaller.
2012-04-17 14:22:48 -04:00
testdata
continuing the BQSR triage...
2012-04-05 14:34:15 -04:00