6d03bce0d3
The most important reason for this change is that we no longer need to read the entire recal file into memory up front in ApplyRecalibration. For 1000G calling this was prohibitive in terms of memory requirements. Now we go through the rod system and pull in just the records we need at a given position. As an added bonus, once BCF2 is live we can drastically cut down the sizes of these recal files (which can grow large for whole genome calling). |
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