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David Roazen 605a5ac2e3 GATK engine: add ability to do on-the-fly BAM file sample renaming at runtime
-User must provide a mapping file via new --sample_rename_mapping_file argument.
 Mapping file must contain a mapping from absolute bam file path to new sample name
 (format is described in the docs for the argument).

-Requires that each bam file listed in the mapping file contain only one sample
 in their headers (they may contain multiple read groups for that sample, however).
 The engine enforces this, and throws a UserException if on-the-fly renaming is
 requested for a multi-sample bam.

-Not all bam files for a traversal need to be listed in the mapping file.

-On-the-fly renaming is done as the VERY first step after creating the SAMFileReaders
 in SAMDataSource (before the headers are even merged), to prevent possible consistency
 issues.

-Renaming is done ONCE at traversal start for each SAMReaders resource creation in the
 SAMResourcePool; this effectively means once per -nt thread

-Comprehensive unit/integration tests

Known issues: -if you specify the absolute path to a bam in the mapping file, and then
               provide a path to that same bam to -I using SYMLINKS, the renaming won't
               work. The absolute paths will look different to the engine due to the
               symlink being present in one path and not in the other path.

GSA-974 #resolve
2013-07-18 15:48:42 -04:00
licensing deleted old license files 2013-07-02 16:36:47 -04:00
protected Last feature request from Reich/Paavo labs: the allSitePLs feature in UG worked but not quite filled requirements. What's needed is the ability to have all 10 PLs for EVERY site, regardless of whether they are variant or not. Previous version only emitted the 10 PLs in reference sites. Problem is that, if all PLs are emitted in all sites and every single site is quad-allelic (only way to have the PLs printed out in a valid way) then the ability to filter variants and to use the INFO fields may be compromised. 2013-07-18 12:54:52 -04:00
public GATK engine: add ability to do on-the-fly BAM file sample renaming at runtime 2013-07-18 15:48:42 -04:00
settings Rev picard, sam-jdk, tribble, and variant to version 1.91.1453 2013-05-07 14:21:15 -04:00
.gitignore Detect stuck lock-acquisition calls, and disable file locking for tests 2013-04-24 22:49:02 -04:00
README.md Update README file for the 2.6 release 2013-06-20 13:08:29 -04:00
build.xml Fail gracefully in the packaging system when bcel is not installed 2013-07-02 15:50:51 -04:00
intellij_example.tar.bz2 Removed the intellij files from the root and made an example package for new users. This allows users to start at the same page and then change it as they see fit without interfering with the repo (thanks guillermo!) 2012-09-27 11:04:56 -04:00
ivy.xml Brought all of ReduceReads to fastutils 2013-02-23 22:53:23 -05:00

README.md

The Genome Analysis Toolkit

See http://www.broadinstitute.org/gatk/