gatk-3.8/public/java/test/org/broadinstitute/sting
Mark DePristo 45fc0ea98d Improvements to indel analysis capabilities of VariantEval
-- Now calculates the number of Indels overlapping gold standard sites, as well as the percent of indels overlapping gold standard sites
-- Removed insertion : deletion ratio for 1 bp event, replaced it with 1 + 2 : 3 bp ratio for insertions and deletions separately.  This is based on an old email from Mark Daly:

    // - Since 1 & 2 bp insertions and 1 & 2 bp deletions are equally likely to cause a
    // downstream frameshift, if we make the simplifying assumptions that 3 bp ins
    // and 3bp del (adding/subtracting 1 AA in general) are roughly comparably
    // selected against, we should see a consistent 1+2 : 3 bp ratio for insertions
    // as for deletions, and certainly would expect consistency between in/dels that
    // multiple methods find and in/dels that are unique to one method  (since deletions
    // are more common and the artifacts differ, it is probably worth looking at the totals,
    // overlaps and ratios for insertions and deletions separately in the methods
    // comparison and in this case don't even need to make the simplifying in = del functional assumption

-- Added a new VEW argument to bind a gold standard track
-- Added two new stratifications: OneBPIndel and TandemRepeat which do exactly what you imagine they do
-- Deleted random unused functions in IndelUtils
2012-04-06 16:07:46 -04:00
..
alignment Reinitialize random seed in the bwa bindings from the fixed seed stored in the 2011-07-22 13:41:53 -04:00
commandline Added ability to specify arguments in files via -args/--arg_file 2011-10-24 15:58:34 -04:00
gatk Improvements to indel analysis capabilities of VariantEval 2012-04-06 16:07:46 -04:00
jna When using bam list mode in HSP deriving VCF name from bam list instead of requiring an additional parameter. 2011-12-16 18:09:25 -05:00
utils Function to compute whether a VariantContext indel is part of a TandemRepeat 2012-04-06 16:07:46 -04:00
BaseTest.java Bug fix: BaseTest change shouldn't have been committed, first cleanup of SNP pool code (more to follow) 2012-04-03 18:55:52 -04:00
MD5DB.java Merged bug fix from Stable into Unstable 2011-10-13 18:02:06 -04:00
MedianUnitTest.java Adding more unit tests and contracts to PairHMM util class. Updating HaplotypeCaller to use the new PairHMM util class. Now that the HMM result isn't dependent on the length of the haplotype there is no reason to ensure all haplotypes have the save length which simplifies the code considerably. 2012-03-05 08:28:42 -05:00
StingTextReporter.java Reorganized the codebase beneath top-level public and private directories, 2011-06-28 06:55:19 -04:00
WalkerTest.java Minor: cleaner way of turning off index-on-the-fly checking in case we want to turn it back on. 2012-03-18 00:53:29 -04:00