gatk3的最后一个经典版本3.8
 
 
 
 
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Mark DePristo 2996693c9f FisherStrand now computed with and without filtering low-qual bases, and least significant pvalue is kept
-- Old way (filtering for Q > 17 bases) resulted in biased FS when the site was good but there was a
systematic shift in the QUAL of REF and ALT between strands of the reads (sometimes happens)
-- New way (taking all bases) was consistent with BaseQualRankSum and other tests, but there can be
a lot of low qual reference bases on one strand in some techs (ION/PROTON/PACBIO) because of the
preference for introducing an indel vs. a mismatch.
-- This implementation allows us to have our cake and eat it to by computing both p-values, and
taking the maximum one (i.e., least significant).
-- No integration tests updated yet -- still exploring the consequences of this change
2012-08-28 08:06:47 -04:00
licensing Revert unintentional license change 2012-08-09 17:10:47 -04:00
protected/java HaplotypeCaller forbids BAQ 2012-08-24 13:25:05 -04:00
public FisherStrand now computed with and without filtering low-qual bases, and least significant pvalue is kept 2012-08-28 08:06:47 -04:00
settings Updating cofoja to the latest version 2012-08-09 16:36:18 -04:00
.gitignore Minor additions to the shared .gitignore file, now that Mark has checked one in. 2011-10-26 12:24:28 -04:00
build.xml Convert external.build.dir and external.dist.dir back to paths 2012-08-15 23:04:10 -04:00
ivy.xml Updating cofoja to the latest version 2012-08-09 16:36:18 -04:00