1444cd753b
-- The logic for determining active regions was a bit broken in the HC when intervals were used in the system -- TraverseActiveRegions now uses the AllLocus view, since we always want to see all reference sites, not just those covered. Simplifies logic of TAR -- Non-overlapping intervals are always treated as separate objects for determing active / inactive state. This means that each exon will stand on its own when deciding if it should be active or inactive -- Misc. cleanup, docs of some TAR infrastructure to make it safer and easier to debug in the future. -- Committing the SingleExomeCalling script that I used to find this problem, and will continue to use in evaluating calling of a single exome with the HC -- Make sure to get all of the reads into the set of potentially active reads, even for genomic locations that themselves don't overlap the engine intervals but may have reads that overlap the regions -- Remove excessively expensive calls to check bases are upper cased in ReferenceContext -- Update md5s after a lot of manual review and discussion with Ryan |
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