bf5ce41321Merge pull request #336 from broadinstitute/gda_ancient_dna_pls
Eric Banks
2013-07-18 10:47:52 -0700
9dd109b79aLast feature request from Reich/Paavo labs: the allSitePLs feature in UG worked but not quite filled requirements. What's needed is the ability to have all 10 PLs for EVERY site, regardless of whether they are variant or not. Previous version only emitted the 10 PLs in reference sites. Problem is that, if all PLs are emitted in all sites and every single site is quad-allelic (only way to have the PLs printed out in a valid way) then the ability to filter variants and to use the INFO fields may be compromised. So, compromise solution is to go back to having biallelic PLs but emit a new FORMAT field, called APL, which has the 10 values, but all other statistics and regular PLs are computed as before. Note that integration test had to be disabled, as the BCF2 codec apparently doesn't support writing into genotype fields other than PL,DP,AD,GQ,FT and GT.
Guillermo del Angel
2013-07-16 11:14:48 -0400
234f564009Merge pull request #335 from broadinstitute/eb_improvements_to_KB_assessment
Eric Banks
2013-07-18 08:47:03 -0700
5d1454c6b0Several improvements to the NA12878 knowledge base.
Eric Banks
2013-07-12 11:46:34 -0400
6440f926d3Parallel tests: use /broad/hptmp as working dir instead of /broad/classA-test
David Roazen
2013-07-15 15:12:31 -0400
f2fca40b2bMerge pull request #333 from broadinstitute/dr_fix_SAMReaderID_hashing
Eric Banks
2013-07-15 12:20:50 -0700
28b8815688Merge pull request #301 from broadinstitute/mc_tsca_project
chartl
2013-07-15 11:21:41 -0700
c15751e41eSAMReaderID: fix bug with hash code and equals() method
David Roazen
2013-07-15 13:28:07 -0400
51b95589e5Merge pull request #331 from broadinstitute/gda_pool_caller_paper
Eric Banks
2013-07-15 09:06:14 -0700
464cf33dd3Committing pool caller script changes for posterity: mostly updating the reference sample calls to latest gold standard, adding filtering tweaks and redo of R scripts.
Guillermo del Angel
2013-06-19 13:27:12 -0400
5d198d3400Added write to likelihoods.txt for batch hmm
Scott Thibault
2013-07-15 10:16:39 -0500
3459eab413Barcodes per Amplicon count tool
Mauricio Carneiro
2013-06-10 13:28:12 -0400
0a8f75b953Merge branch 'master' into st_fpga_hmm
sathibault
2013-07-15 08:17:32 -0500
1575fdaab4Merge pull request #330 from broadinstitute/yf_adding_per_sample_allele_biased_downsampling_to_HC
Eric Banks
2013-07-13 18:50:32 -0700
8c07614321QualifyMissingIntervals: support different formats
Mauricio Carneiro
2013-07-10 16:16:28 -0400
afcf7b96db- Added per-sample AlleleBiasedDownsampling capability to HaplotypeCaller - Added integration test to show that providing a contamination value and providing same value via a file results in the same VCF
Yossi Farjoun
2013-07-10 08:06:54 -0400
7ddf85c040Merge pull request #329 from broadinstitute/eb_more_sensitivity_improvements_to_the_HC
delangel
2013-07-12 10:37:43 -0700
b16c7ce050A whole slew of improvements to the Haplotype Caller and related code.
Eric Banks
2013-06-28 07:41:06 -0400
3e1a96844bMerge pull request #328 from broadinstitute/dr_dependency_analyzer_output_loader
Eric Banks
2013-07-11 20:31:17 -0700
8ef4e6c9f7DependencyAnalyzerOutputLoader: allows output from the dependency analyzer to be loaded and queried
David Roazen
2013-07-11 14:55:05 -0400
ccc0ee5b4dMerge pull request #327 from broadinstitute/gda_large_indel_improvement
Eric Banks
2013-07-11 06:58:13 -0700
a8ea57df9eMerge branch 'master' of github.com:broadinstitute/gsa-unstable
Menachem Fromer
2013-07-10 16:44:35 -0400
aba55dbb23Moved some HC parameters related to active region extensions to command line arguments so that they're more easily modified. Some of these parameters need tinkering in order to call some large indels. See GSA-891 and subtasks for particular examples thereof.
Guillermo del Angel
2013-07-10 14:29:13 -0400
2d81234ed8Merge pull request #326 from broadinstitute/dr_dependency_analyzer_add_manual_dependencies
droazen
2013-07-09 10:12:50 -0700
de06eda6acDependency analyzer improvements
David Roazen
2013-07-08 14:27:58 -0400
5dbb582be7Merge pull request #310 from broadinstitute/mc_interval_list_to_fastq
Eric Banks
2013-07-08 14:30:43 -0700
380a01ddc0Merge pull request #322 from broadinstitute/eb_add_review_indexes_to_repo
Eric Banks
2013-07-08 10:15:46 -0700
4fe26ea2cfMerge pull request #323 from broadinstitute/eb_fix_sorting_in_reduce_reads
Eric Banks
2013-07-08 10:15:28 -0700
c5a2a8f39fMerge pull request #324 from broadinstitute/eb_AnalyzeCovariates_is_not_deprecated
Eric Banks
2013-07-08 10:15:10 -0700
bc28a1f236pipeline test runner: create temp dir if it doesn't exist
David Roazen
2013-07-08 12:34:20 -0400
1c28bd2ffdMerge pull request #325 from broadinstitute/dr_general_calling_pipeline_walker_list
Ryan Poplin
2013-07-08 09:28:13 -0700
46b453a69dList of walkers used by the GeneralCallingPipeline
David Roazen
2013-07-08 11:53:58 -0400
73fc7f6ab1Reduce Reads output should never be expected to be sorted (hence the need to sort on disk) but for some reason it was with -nwayout mode.
Eric Banks
2013-07-08 10:33:36 -0400
921f551426AnalyzeCovariates is no longer a deprecated tool.
Eric Banks
2013-07-08 09:48:12 -0400
3e357ac8cfIt was annoying me that these index files kept showing up in 'git status'
Eric Banks
2013-07-08 09:46:08 -0400
0aa9d02570Merge pull request #321 from broadinstitute/eb_fix_annotating_multiple_comps
Mark DePristo
2013-07-05 05:05:09 -0700
5f5c90e65cFix bug introduced recently in the VariantAnnotator where only the last -comp was being annotated at a site.
Eric Banks
2013-07-05 00:04:52 -0400
6d69c7dc71Disable RetryMemoryLimit pipeline test
David Roazen
2013-07-03 13:38:28 -0400
8d00e558fbMerge pull request #317 from broadinstitute/dr_dependency_analyzer
Tadeusz Jordan
2013-07-03 08:46:37 -0700
7cdb7ac572Merge pull request #320 from broadinstitute/gg_cleanup_licenses_PT51255639
Mark DePristo
2013-07-03 04:55:15 -0700
d55dddfdbadeleted old license files
Geraldine Van der Auwera
2013-07-02 16:36:47 -0400
3db02e5ef1Merge pull request #315 from broadinstitute/md_ref_conf_hc
Mark DePristo
2013-07-02 13:04:33 -0700
2e87d09c26Merge pull request #319 from broadinstitute/dr_packaging_system_fail_gracefully_when_bcel_not_installed
droazen
2013-07-02 13:01:45 -0700
75d1f64416Fail gracefully in the packaging system when bcel is not installed
David Roazen
2013-07-02 15:46:34 -0400
35cdc16822Merge pull request #318 from broadinstitute/dr_improve_dcov_documentation
Mark DePristo
2013-07-02 12:47:29 -0700
5f34054cc1Remove filtering of MAPQ 0 reads from CalledHaplotypeBAMWriter
Mark DePristo
2013-07-01 14:55:15 -0400
7be01777f6Bugfix for incPos in GenomeLoc
Mark DePristo
2013-07-01 14:51:15 -0400
ed0b1c5abaFix bug in ReadThreadingAssembler in cycle failures causing NPE
Mark DePristo
2013-06-25 10:53:33 -0400
e3e8631ff5Working version of HaplotypeCaller ReferenceConfidenceModel that accounts for indels as well as SNP confidences
Mark DePristo
2013-06-19 15:07:35 -0400
41aba491c0Critical bugfix for adapter clipping in HaplotypeCaller
Mark DePristo
2013-06-27 15:44:53 -0400
cdea744b95Improve -dcov documentation to address recent user confusion
David Roazen
2013-07-02 15:27:36 -0400
8eab59419dAnt-based walker dependency analyzer
David Roazen
2013-06-25 15:18:47 -0400
9df58314abBugfix for counting of applied filters
Mark DePristo
2013-07-01 21:09:48 -0400
c3d59d890dUpdate licenses for new PbsEngine* classes
David Roazen
2013-07-01 15:50:20 -0400
2964ebaa4eMerge pull request #314 from broadinstitute/ks_francesco_pbs_patch
droazen
2013-07-01 12:39:38 -0700
f0c36e2890Fixing failed test for HSP by changing dcov from 60 to 200.
Khalid Shakir
2013-07-01 11:39:18 -0400
ec206eccfcSwitch "all" test pipeline job runners to mean the job runners that run at The Broad.
Khalid Shakir
2013-06-27 15:07:59 -0400
acf90ca027corrected number of arguments passed to PbsEngineJobRunner when requesting multiple cores
Francesco
2013-06-27 11:08:59 +0200
948b2fca20added PbsEngine plugin into engine folders, to be called in Queue with -jobRunner PbsEngine; the plugin is written modifying the existing GridEngine plugin, used as a template
Francesco
2013-06-26 10:29:45 +0200
4ec50caea2Merge pull request #313 from broadinstitute/mc_generalize_dt_scala_script
Mark DePristo
2013-06-29 11:00:00 -0700
a6b569b395Added all the parameters to the scala script for DiagnoseTargets
Mauricio Carneiro
2013-06-25 15:17:40 -0400
815f119f7cWalker to create a fastq file from an interval list
Mauricio Carneiro
2013-06-26 23:51:22 -0400
31827022dbFix pipeline tests that were not respecting the pipeline test dry run setting
David Roazen
2013-06-28 14:57:16 -0400
82dcdc01c0Merge branch 'master' into st_fpga_hmm
Scott Thibault
2013-06-28 10:13:05 -0500
e691fa3e19FPGA null pointer bug fix
Scott Thibault
2013-06-28 08:52:09 -0500
1ec56c9e64Merge pull request #311 from broadinstitute/eb_require_min_mq_for_FN_in_kb
Ryan Poplin
2013-06-27 16:49:45 -0700
5717f3dc1cMerge pull request #312 from broadinstitute/eb_fix_assessna12878_and_add_integration_tests
Mark DePristo
2013-06-27 13:51:37 -0700
7aa1f56dffWe need to enforce a minimum base and mapping quality threshold to penalize a callset for FNs.
Eric Banks
2013-06-27 10:47:05 -0400
1f1da56d28I allowed a bad push yesterday with the KB because there weren't any integration tests for the assessment.
Eric Banks
2013-06-27 15:40:19 -0400
825b603acbMerge pull request #298 from broadinstitute/md_likelihood_rank_sum
Ryan Poplin
2013-06-27 11:14:25 -0700
de7fe2e086Merge pull request #308 from broadinstitute/rp_assessment_low_coverage
Mark DePristo
2013-06-27 06:46:23 -0700
9f08718636Merge pull request #309 from jsilter/master
Eric Banks
2013-06-26 16:00:51 -0700
beb834e849Add "isComplexEvent" as attribute to VariantContextBuilder for MongoVariantContext
Jacob Silterra
2013-06-26 17:12:32 -0400
fe5348ea5dDon't count no coverage sites as false negatives in the assessment against the knowledge base
Ryan Poplin
2013-06-26 16:02:44 -0400
a514dd0643Merge pull request #307 from broadinstitute/eb_rr_off_by_one_error
Mark DePristo
2013-06-26 13:02:23 -0700
876e40466aProper fix for previous RR -cancer_mode fix.
Eric Banks
2013-06-26 14:48:09 -0400
95eab80f9bMerge pull request #306 from broadinstitute/eb_make_assessreducedquals_hidden
Eric Banks
2013-06-26 08:47:28 -0700
f242be12c0Make this walker @Hidden
Eric Banks
2013-06-26 11:45:21 -0400
28d4c3debcMerge pull request #305 from broadinstitute/dr_move_DownsampleReadsQC_to_private
Mark DePristo
2013-06-25 16:33:20 -0700
94294ed6c4Move DownsampleReadsQC walker to private
David Roazen
2013-06-25 15:48:44 -0400
d13ed06e9dMerge pull request #303 from broadinstitute/eb_update_kb_to_use_exome_intervals
Mark DePristo
2013-06-24 13:06:52 -0700
6dc816beeeVarious updates to have the KB use the expanded exome intervals (from D MacArthur) in addition to chr20.
Eric Banks
2013-06-17 13:21:21 -0400
ff76d0c877Merge pull request #304 from broadinstitute/eb_rr_header_negative_fix_again
Mark DePristo
2013-06-24 11:55:52 -0700
165b936fcdFixing the 'header is negative' problem in Reduce Reads... again.
Eric Banks
2013-06-24 14:06:21 -0400
b97f9a487dMerged bug fix from Stable into Unstable
Valentin Ruano-Rubio
2013-06-24 14:00:01 -0400
521d9c1df5Merge pull request #302 from broadinstitute/mc_processing_pipeline2
Mark DePristo
2013-06-24 09:52:55 -0700
c38b8065d8quick fixes to the scala script
Mauricio Carneiro
2013-04-25 20:13:20 -0400
191e4ca251Merge pull request #300 from broadinstitute/mc_move_qualify_intervals_to_protected
Mark DePristo
2013-06-24 09:35:45 -0700