hanna
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596773e6c6
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Cleanup.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@931 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-07 20:25:08 +00:00 |
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hanna
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e6aa058ec4
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Tighten up error handling a bit.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@920 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-06 03:40:50 +00:00 |
depristo
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819862e04e
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major restructuring of generalized variant analysis framework. Now trivally easy to add additional analyses. Easy partitioning of all analyses by features, such as singleton status. Now has transition/transversional bias, counting, dbSNP coverage, HWE violation, selecting of variants by presence/absense in dbs. Also restructured the ROD system to make it easier to add tracks. Also, added the interval track -- if you provide an interval list, then the system autoatmically makese this available to you as a bound rod -- you can always find out where you are in the interval at every site. Python scripts improved to handle more merging, etc, into population snps.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@918 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-05 23:34:37 +00:00 |
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hanna
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050d55cdb0
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Basic graph support for testing.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@916 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-05 21:04:01 +00:00 |
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hanna
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2035d7dfd3
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Revert some debug code in RecalQual.py. Make LogisticRegression easier to Ctrl-C out of.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@904 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-05 01:53:48 +00:00 |
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hanna
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61ae00c7bf
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Lots of cleanup.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@903 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-05 01:26:10 +00:00 |
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hanna
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9689bb3331
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Very early draft of script integrating the covariant counting / logistic regression. Deleted some unused code and spurious debug info.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@902 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-04 22:52:11 +00:00 |
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hanna
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40bc4ae39a
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The building blocks for segmenting covariate counting data by read group.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@899 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-04 19:55:24 +00:00 |
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depristo
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67112c79a1
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More robust individual genotypes to population script
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@893 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-04 00:12:31 +00:00 |
andrewk
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7755476d36
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Updated coverter to reflect change in contig ordering in Geli files
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@888 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-03 10:05:28 +00:00 |
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andrewk
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080af519cb
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Added R script and uncommented a line in recal_qual.py
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@886 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-03 03:15:45 +00:00 |
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andrewk
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b2eb724456
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First commit of recalibration master control script for recalibrating quality scores.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@885 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-03 02:17:10 +00:00 |
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depristo
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3998085e4b
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more and better python scripts for dealing with calls
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@881 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-02 20:37:19 +00:00 |
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andrewk
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587d07da00
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Merged functionality of two python scripts into LogRegression.py, some clarity updates to covariate and regression java files.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@876 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-02 16:55:05 +00:00 |
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depristo
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ae2eddec2d
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Improving, yet again, the merging of bam files
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@874 348d0f76-0448-11de-a6fe-93d51630548a
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2009-06-02 13:31:12 +00:00 |
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depristo
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543c68cdd8
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First version of individual geli files to population SNPS
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@865 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-31 15:29:10 +00:00 |
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depristo
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6adef28b97
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Now supports automatic merging by population
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@864 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-31 15:28:44 +00:00 |
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depristo
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e0803eabd9
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enabled underlying filtering of zero mapping quality reads, vastly improves system performance
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@853 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-29 14:51:08 +00:00 |
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depristo
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c72601322a
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now returns the farm id when submitting a job!
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@825 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-26 22:23:24 +00:00 |
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depristo
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04e51c8d1d
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Better version of MergeBAMBatch -- more options for creating the file
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@787 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-21 22:26:19 +00:00 |
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depristo
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3b1f84e15b
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Slightly improved interface to merging utility for multiple bam files
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@757 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-20 12:54:41 +00:00 |
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depristo
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e9f85ef920
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Better merge support
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@748 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-18 21:18:51 +00:00 |
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depristo
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9dec783a82
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Actually writes out a good header now
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@744 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-18 13:34:52 +00:00 |
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depristo
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8e9e2f4502
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Revised ROD system. Split the system in Basic type and interface. Enabled more control over rod accessing, including an initialize() function to fetch headers and other options from the file. Added general tabular rod, which has a named columns and supports a map<String,String> interface. Comes with shiny new Junit system for RODs. Also, added simple python script for accessing picard data.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@716 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-14 21:06:28 +00:00 |
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hanna
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de1c282e62
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Reference-ordered data relies on bugs in the old command-line argument system to work. Update the ROD system to from -B track1 type1 file1 track2 type2 file2 to -B track1,type1,file1 -B track2,type2,file2.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@640 348d0f76-0448-11de-a6fe-93d51630548a
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2009-05-08 15:28:19 +00:00 |
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depristo
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30218ee31a
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Better validation scripts and data
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@562 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-29 17:40:07 +00:00 |
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andrewk
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58b2578c44
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Several changes to CovariateCounter walker to print more tables (called vs. observed Q scores), bug fixes to LogisticRecalibrationWalker and LogisticRegressor, and print string functionality added to Pair.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@550 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-28 00:37:48 +00:00 |
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depristo
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3739682bef
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Actually has working version of the python script to merge multiple bam files
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@530 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-24 19:15:55 +00:00 |
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depristo
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40a2b3eeb3
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Basic logistic regression support for calibrating qualities; mostly for Andrew to experiment with
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@529 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-24 19:09:50 +00:00 |
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andrewk
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38c2f73457
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LogRegression.py script that converts parameter files for each dinucleotide regression into one file to be read in by correction script.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@528 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-24 18:31:26 +00:00 |
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depristo
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b8a6f6e830
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Support for indexBAM command
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@496 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-22 19:39:07 +00:00 |
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depristo
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e842b543c9
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Better validation scripts
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@458 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-16 23:18:00 +00:00 |
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depristo
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f47f640df6
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Better debugging output and testing
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@455 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-16 21:54:56 +00:00 |
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depristo
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2eabcfedb7
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Fixed potential bug with next() operation returning empty contexts when a read contains a large deletion. We can now use the look ahead safely...
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@439 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-15 21:41:30 +00:00 |
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depristo
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72a3d84ed2
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General purpose pileup code -- you can use these features to obtain detailed pileup data from reads and offsets. Useful for all pileup based walkers. Expanded support for rodSAMPileup to enable the new ValidatingPileupWalker, which takes a samtools pileup output and checks that GATK gives identical output as samtools on a per base and per qual pileup. It's going to be a very useful validation tool.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@418 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-14 22:13:10 +00:00 |
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depristo
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49b2622e3d
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Helper utility for merging BAM files
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@345 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-09 20:10:41 +00:00 |
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depristo
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9d35f0ca67
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The system now requires a dictionary file for a fasta file, or it throws an error. You can't just operate without a sequence dictionary any longer. We will transition to a GenomeLoc system that assumes a dictionary is available.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@320 348d0f76-0448-11de-a6fe-93d51630548a
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2009-04-07 22:21:57 +00:00 |
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andrewk
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9dee9ab51c
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Added Hapmap data track (using rodGFF class for GFF file format) to toolkit as a command line option, Hapmap metrics to AlleleFrequencyMetricsWalker, and a python Geli2GFF file converter.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@163 348d0f76-0448-11de-a6fe-93d51630548a
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2009-03-24 03:58:03 +00:00 |
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hanna
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2ee2623926
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Move non-java code out of playground.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@154 348d0f76-0448-11de-a6fe-93d51630548a
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2009-03-23 19:31:38 +00:00 |
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hanna
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5031875507
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Move to new directory organization.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@35 348d0f76-0448-11de-a6fe-93d51630548a
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2009-03-11 20:58:01 +00:00 |
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depristo
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bd1fadd9fe
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Validating walker for lots of bam files
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@10 348d0f76-0448-11de-a6fe-93d51630548a
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2009-02-28 17:05:08 +00:00 |
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depristo
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e892c3fd98
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Shouldn't be in the tree
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@9 348d0f76-0448-11de-a6fe-93d51630548a
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2009-02-28 15:31:17 +00:00 |
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depristo
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17aabb38f9
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Basic reorganization of tree
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@8 348d0f76-0448-11de-a6fe-93d51630548a
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2009-02-28 15:28:56 +00:00 |