Samuel Friedman
f5d133df87
scientific notation in model report and basic test
2017-05-03 18:37:52 -04:00
Samuel Friedman
4df71a3ca1
expect floats in the report
2017-05-02 12:05:10 -04:00
Samuel Friedman
1b4ac51048
move model file parsing to initialize
2017-05-01 15:52:45 -04:00
Samuel Friedman
d06a6c7318
string cast bug
2017-04-28 17:32:36 -04:00
Samuel Friedman
f55b932cfc
addressed review comments
2017-04-27 17:16:57 -04:00
Samuel Friedman
85cb1c2810
dont spam on NaNs
2017-04-26 17:33:06 -04:00
Samuel Friedman
57c064eaa3
small code cleanup
2017-04-26 16:02:06 -04:00
Samuel Friedman
a8f70c891f
Create GMM from model reports in VQSR
2017-04-26 16:02:06 -04:00
Ron Levine
c20e682a97
Update MuTect2 documentation about not computing obvious germline variants
2017-03-21 17:54:52 -04:00
Ron Levine
687dee22ac
Fix CombineVariants merge for different types
2017-03-14 16:42:16 -04:00
Ron Levine
49083fc704
Fix FindCoveredIntervals so -minBQ, -minMQ and -cov work as expected
2017-03-07 16:58:23 -05:00
Ron Levine
8316fa92f3
Set AD and DP to zero if no read coverage
2017-02-28 16:56:45 -05:00
Ron Levine
61875e4dfa
Fix LeftAlignAndTrimVariants -split to not change no-call genotypes to hom-ref
2017-02-22 17:57:59 -05:00
Ron Levine
3c347c1385
Total ploidy does not have to equal to the number of priors
2017-02-20 20:28:41 -05:00
Ron Levine
1d36d9fd69
Move htsjdk to ver 2.9.0 and picard to ver 2.8.3
2017-02-17 07:03:03 -05:00
Ron Levine
dce2e29ade
Change ALLOW_N_CIGARS to ALLOW_N_CIGAR_READS in doc
2017-01-18 15:11:52 -05:00
Ron Levine
7c0e51396f
Merge pull request #1539 from broadinstitute/rhl_hc_disable_badmatefilter_1443
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Allow disabling of BadMateFilter in HaplotypeCaller
2017-01-18 12:39:22 -05:00
Ron Levine
1f6645539a
Make upstreamDeletionsLoc ThreadLocal
2017-01-12 14:09:24 -05:00
Ron Levine
f092e1438d
Allow disabling of BadMateFilter in HaplotypeCaller
2017-01-11 14:49:45 -05:00
Ron Levine
44c0609418
Log annotation warning once if using multithreads
2017-01-08 09:58:40 -05:00
Ron Levine
4f52395795
Synchronize modification/access to practicalAlleleCountForPloidy
2017-01-06 22:16:35 -05:00
Ron Levine
ab4a9fa64f
Update stand_call_conf doc strings
2017-01-06 17:15:56 -05:00
Geraldine Van der Auwera
e86da63d04
Update pom versions to mark the start of GATK 3.8 development
2016-12-12 08:53:23 -05:00
Geraldine Van der Auwera
56f2c1ac75
Update pom versions for the 3.7 release
2016-12-12 08:49:43 -05:00
Ron Levine
5602095a24
Move htsjdk to ver 2.8.1 and picard to ver 2.7.2
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- Updating VF and tests to match new jexl behavior from htsjdk
- Use Z instead of DP to test behavior on missing annotation
2016-12-10 11:50:30 -05:00
meganshand
1291cfa881
Merge pull request #1529 from broadinstitute/ms_fs
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Make Fisher Exact Test match R and GATK4 p-values
2016-12-06 08:55:08 -05:00
Ron Levine
172db666d6
Output files with the vcf.gz extension are gzipped, containing .bcf not as an extension result in VCF"
2016-12-05 22:25:59 -05:00
Geraldine Van der Auwera
234ccdf0c3
Merge pull request #1496 from broadinstitute/db_m2_downsampling
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Expose downsampling parameters as CLI arguments to Mutect2
2016-12-05 21:53:25 -05:00
meganshand
3265a664c4
Makes Fisher's exact test match R and GATK4
2016-12-05 16:46:47 -05:00
David Benjamin
b1f2301dd3
Add downsampling arguments to Mutect
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- maxReadsInRegionPErSample, minReadsPerAlignment start are now M2 args
- maxReadsInMemoryPerSample is an activeRegionWalker arg
2016-12-05 14:12:22 -05:00
Geraldine Van der Auwera
b42dc1624b
Documentation fixes
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- Fix missing closing code block tag
- SOR fix + minor fix to template
- Minor typo fixes
- Make no_cmdline_in_header arg visible in docs
- Caveats for UG-only args that are difficult to move out of common collection
- Reference -L and -XL in -gvcf documentation
- Annotation doc fixes (dsde-docs#1289)
- Unhide some ContEst args and make Advanced
- Fix inputPrior error message
- Update web urls
- Add JEXL doc link
2016-12-05 14:09:44 -05:00
Ron Levine
68b6f8f638
Replace VariantContextWriterFactory with VariantContextWriterBuilder
2016-11-30 16:04:25 -05:00
David Benjamin
055d653bc2
Merge pull request #1517 from broadinstitute/rhl_adapter_boundary_err_1406
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Fix adapter bounday for positive strand
2016-11-18 10:25:46 -05:00
Ron Levine
22d94a7096
Fix adapter bounday for positive strand
2016-11-16 16:41:17 -05:00
David Benjamin
6156b85ad9
Fixed logic error and tidied AlleleBalance and AlleleBalanceBySample
2016-11-16 14:10:48 -05:00
Ron Levine
d61b4c7e91
Change the truth VCF
2016-11-15 14:56:15 -05:00
Geraldine Van der Auwera
2b83dd7c5b
Added TreeReduce interface to VariantFiltration
2016-11-14 17:19:44 -05:00
Ron Levine
bcbd7fe952
Change default value of STANDARD_CONFIDENCE_FOR_CALLING to 10
2016-11-11 02:06:41 -05:00
Ron Levine
df0ba2ce8d
BaseCountsBySample counting bases at a particular position
2016-11-08 13:31:05 -05:00
David Benjamin
029632eb1c
backport numerics changes in new qual
2016-11-01 03:16:21 -04:00
Steve Huang
cc91052e69
fixed a max priority Q error while removing alt alleles when faced with high ploidy and allele count; added hackish integration test ( #1457 )
2016-10-27 11:19:49 -04:00
Ron Levine
01a858542f
Remove RankSumTest and RMSAnnotation from hom-ref sites
2016-10-14 11:34:54 -04:00
Valentin Ruano Rubio
16417bbf34
Fixes NaN issue in new Qual calculator
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Fixes issue #1491
2016-10-11 16:03:06 -04:00
Ron Levine
81a9ece45b
deprecate -stand_emit_conf
2016-10-09 10:24:09 -04:00
Ron Levine
4ef396f72e
Assign correct ambiguity code for * allele
2016-09-22 11:02:44 -04:00
David Benjamin
318bee2269
Backport new AFCalculator
2016-09-21 15:21:56 -04:00
Ron Levine
c13e3752d6
Move htsjdk to ver 2.6.1 and picard to ver 2.6.0
2016-09-16 16:36:52 -04:00
Ron Levine
6564066de3
Remove NON_REF from allSites VCF output
2016-09-16 13:55:52 -04:00
Steve Huang
091d05370b
Fix 1448 to make alt allele removal by likelihoods robust to ref allele indices ( #1475 )
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* alt alle removal by likelihoods now robust to ref allele indices (no longer assumes 0-indexed ref)
2016-09-13 21:20:44 -04:00
Ron Levine
a7b1130224
Do not emit GVCF block definitions in the header
2016-09-09 07:41:03 -04:00