Commit Graph

266 Commits (e4a67f3df17ec4f3ca5fbd2bafc7c9f768b29f64)

Author SHA1 Message Date
Kiran V Garimella 051c1dc639 Merge branch 'master' of ssh://copper.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-22 15:59:00 -04:00
Mark DePristo f0be7348be Generalized handler to allow it to be used with any arbitrary class structure.
DocumentedGATKFeature now includes a field for the group name.
Build.xml works with public / private now.
2011-07-22 14:07:40 -04:00
Matt Hanna f50145b872 Reinitialize random seed in the bwa bindings from the fixed seed stored in the
BWA support files every time the support files are loaded.
2011-07-22 13:41:53 -04:00
Mark DePristo 453954182e Generalized the documentation system to use a class-specific annotation and processor.
Need to generalize and bug fix the system.  But at a high level it's working now.
2011-07-22 13:18:33 -04:00
Kiran V Garimella b8a0fd2a8d Multiply fractionRandom by 100.0 so that the line that indicates the percentage of variants that will be output says (for instance) 90%, not 0.9% 2011-07-22 11:54:59 -04:00
Mark DePristo 9e88d51db9 Removed now unused @version tags from walker docs. 2011-07-22 09:57:03 -04:00
Mark DePristo 421b70ca4f Removed previous, and largely unused, help system extensions.
This involved deleting the utils/help/*Taglet.java classes, which parsed out these fields unnecessarily
This also involved removing the few uses of these from the codebase.  For these uses, though, almost all were an identical copy of the first line of the docs, which is the default javadoc behavior anyway.
2011-07-22 09:42:44 -04:00
Mark DePristo 172b35372b Moved all of the distributed GATK code to archive. 2011-07-22 09:20:32 -04:00
Khalid Shakir 8b8f121cfb Merge branch 'master' of ssh://gsa3.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-21 23:01:11 -04:00
Khalid Shakir 59eb1f4663 Memory limits changed from Int to Double.
Updated LSF calls to read memory units from config along with tweaks to select hosts.
Moved some common code from GridEngine and LSF to super classes.
2011-07-21 22:57:18 -04:00
Mark DePristo 81d0cab27e Walker index html now emited. 2011-07-21 16:01:54 -04:00
Mark DePristo e892489696 V2 of the document system.
Now uses GATKDoc class to organize documentation for arguments.
Arguments now listed by feature (required, optional, hidden, etc) and link to detailed information about the argument in the html
Lots of code moving between Class and ClassDoc objects.  Should be refactored into a single static utility class.
2011-07-21 15:20:34 -04:00
Christopher Hartl 2f5d10d16b Fix bug wherein aligner could be closed prior to its being used to lowercase sequences. 2011-07-21 13:21:48 -04:00
Matt Hanna 7054c5342f When using the BWA bindings, you have to explicitly call close() to get the
bindings to release memory.
It may or may not be possible to implicitly close triggered by the GC; I'll add a JIRA.
2011-07-21 12:13:29 -04:00
Christopher Hartl 15610ce0c3 Per Matt's request, disabling BWA-based integration tests so he can assess bamboo memory usage. 2011-07-21 11:04:22 -04:00
Mark DePristo 6fa17d86ae Completely hacked together version of a FreeMarker + javadoc + custom doclet walker documentation generator 2011-07-21 00:18:07 -04:00
Mark DePristo 45c73ff0e5 Runs and emits an HTML document 2011-07-20 17:16:33 -04:00
Mark DePristo d31b176e15 Removed GATK use of distributed parallelism framework.
Moved distributed GATK prototype code into distributedutils, separating from threading package
2011-07-20 16:26:09 -04:00
Guillermo del Angel 0a1d2df8cb Merged bug fix from Stable into Unstable 2011-07-20 13:19:35 -04:00
Guillermo del Angel f15023b7d2 Bad bug fix: output GLs in multiallelic records were in incorred order (misread spec) 2011-07-20 12:10:48 -04:00
Guillermo del Angel b9c9e0e952 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-20 10:45:16 -04:00
Guillermo del Angel 7140280bf6 Further bug fixes/cleanups for PrintReadsWalker 2011-07-20 10:44:37 -04:00
Guillermo del Angel a2d90a3590 Bug fix: reverted logic so that default behavior skips over sample lookup 2011-07-20 10:23:10 -04:00
Guillermo del Angel e8409c80fa Further protection vs null pointers in PrintReadsWalker 2011-07-19 21:59:24 -04:00
Christopher Hartl 5d706c9e92 Merge branch 'master' of ssh://chartl@tin.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable
Removing PSP and CSM

Conflicts:

	public/java/src/org/broadinstitute/sting/gatk/walkers/sequenom/CreateSequenomMask.java
	public/java/src/org/broadinstitute/sting/gatk/walkers/sequenom/PickSequenomProbes.java
2011-07-19 20:25:33 -04:00
Guillermo del Angel fb2d475c22 Bug fix to prevent null pointer 2011-07-19 20:13:56 -04:00
Christopher Hartl 92c7cfa1c8 BWA bindings and tests moved to public (was required for ValidationAmplicons)
Integration tests for ValidationAmplicons. New argument to disable BWA, lowercase letters only for repetitiveness instead.
2011-07-19 20:11:31 -04:00
David Roazen baae381acb Revert "Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable"
This reverts commit 039a6bb01f345322ce2be50ae3634308bb24e77e, reversing
changes made to b9c9973d1c638dfc9f8c19b5eb845e99844f9d29.
2011-07-19 18:38:53 -04:00
Christopher Hartl 07e716d23a PickSequenomProbes2 expanded functionality: lowercasing based on sequence uniqueness, preserving reference base prior to indel (not a part of the VC as I thought it was), masking deletion bases with 'N's, flanking insertion with 'N's, output is a fasta formatted file. Renamed to ValidationAmplicons since this is really not for picking sequenom probes, but for generating amplicon sequence from which other applications (like sequenom) can choose PCR primers. Moved from private to public. 2011-07-19 15:21:47 -04:00
Guillermo del Angel 6181d1e4cb Fixed integration test for VariantsToTable: now the * in REF column is not output 2011-07-19 14:42:11 -04:00
Guillermo del Angel e6d306458c Merge bug fixes 2011-07-19 14:36:20 -04:00
Guillermo del Angel 989dd17f95 a) Add ability in PrintReads to specify a sample file to easily subset samples, useful for IGV visualization, b) VariantsToTable is more R-friendly with Indels when printing ref/alt columns, c) Changes to SelectVariants ability to speficy a mask to randomly sample from a given AF distribution 2011-07-19 14:29:07 -04:00
Mark DePristo 8f0badc52b Updating md5s, as the diffobjects walker now emits the summary in reverse order. 2011-07-18 15:44:21 -04:00
Mark DePristo c05451047c Support for multiple records at the same site. The first record gets chr:start, and subsequent records get chr:start_2, chr:start_3, etc. 2011-07-18 15:43:52 -04:00
Mark DePristo 782a05e9b5 Support for sorting the diff output in reverse order. 2011-07-18 15:43:01 -04:00
Mark DePristo 45702d3084 Now supports a mode where the primary key isn't sorted. In this case the records are displayed in the order in which they are added to to the table. 2011-07-18 15:40:15 -04:00
Eric Banks 83ba2c066a Making it deterministic 2011-07-18 13:59:02 -04:00
Eric Banks 92fa410450 Check that it's a valid bam file before parsing or bad things can happen 2011-07-18 13:43:34 -04:00
Eric Banks 80b5c5261a CombineVariants no longer combines records of different types. So now when combining SNP and indel callsets, overlapping calls get their own records. Useful for Khalid in the pipeline. For those interested, it turns out the previous behavior was doing the wrong thing occasionally (and this was even captured in the integration tests). 2011-07-18 13:42:45 -04:00
Eric Banks bc8b5da698 Added docs while I was reading through the code to understand it 2011-07-18 12:25:54 -04:00
Mark DePristo 51b0dd01c3 Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-18 10:47:29 -04:00
Mark DePristo d6e2e89f99 Walker test system refactoring. All MD5DB related functions are now in MD5DB.java.
System has the concept of a local and a global MD5 db.  The local one is like it operated previously.  The global one lives in /humgen/gsa-hpprojects/GATK/data/integrationtests.  If the system can find this directory then MD5s will also be read / written to this location.  This means that gsabamboo will print differences as appropriate.  And all users will in effect have access to a complete history of MD5 file results.
A few minor code reshuffles changed VariantRecalibration and VCFHeader test files.
2011-07-18 10:46:01 -04:00
Mark DePristo 6f26c07b85 Removed the SpecificDifference class. Now Difference classes always have the option to remember specific master and test values. This means that all summarized differences carry with them specific examples of their differences. Consequently, now even summarized differences give at least one example of the specific difference, even when the count of the difference is > 1. Unit tests updated. Added DiffObjects integrationtest. VCFDiffableReader now specifically reads the first line of the VCF file to capture the version number. 2011-07-18 10:42:35 -04:00
Kiran V Garimella b2b7d27fed Merge branch 'laptop' 2011-07-18 00:25:46 -04:00
Kiran V Garimella 497721a799 Added class documentation string. 2011-07-18 00:25:21 -04:00
Kiran V Garimella ac9c66138d Merge branch 'master' of ssh://copper.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-18 00:20:33 -04:00
Kiran V Garimella 824100e57f Corrected typo in MergeAndMatchHaplotypes integration test 2011-07-17 22:50:54 -04:00
Kiran V Garimella 8167aba601 Moved (poorly named) MergeAndMatchHaplotypes to public. Added integration test 2011-07-17 22:47:32 -04:00
Kiran V Garimella afb506e128 Added MD5s for PhaseByTransmission integration tests 2011-07-17 21:55:33 -04:00
Kiran V Garimella 558e197989 Integration test for PhaseByTransmission 2011-07-17 21:25:08 -04:00
Mark DePristo 9992c373be Optimize imports run on the whole project, public and private. I just got too tired of all of the unused imports floating around. Confirmed that the system builds after the changes. 2011-07-17 20:29:58 -04:00
Kiran V Garimella 4ea433f8e1 Moved PhaseByTransmission to public 2011-07-17 19:42:00 -04:00
Mark DePristo 9ca9cf52ac Uncommenting a stray commented test. 2011-07-17 15:38:33 -04:00
Mark DePristo 4db2b13e9e Rev tribble.
Just added more documentation for diffEngine and pointer to new wiki:

http://www.broadinstitute.org/gsa/wiki/index.php/DiffEngine
2011-07-17 13:05:04 -04:00
Mark DePristo 92a1c0c278 Moved the varianteval/tags/DataPoint.java and varianteval/tags/Analysis.java to varianteval/utils. This allows rsync to see these files with the -C option, as tags is some kind of reserved CVS keyword. 2011-07-17 10:14:23 -04:00
Mark DePristo eacf205f40 Tests needed to be updated to reflect the code reorg of tribble. 2011-07-16 09:22:34 -04:00
Menachem Fromer 72f4cf9c0e Walker to perform deterministic annotation of phasing by transmission (to be compatible with RBP's definition of consecutive pairwise phasing) 2011-07-15 17:44:31 -04:00
Guillermo del Angel 9d59c2cb61 a) Made indel VQSR consensus script operational again, b) Made VariantsToTable more indel-friendly when printing out REF and ALT fields: strip out * from REF and print out alleles in the same way as the VCF so that offline processing is easier 2011-07-15 10:13:02 -04:00
Guillermo del Angel 10cf9245d7 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-14 19:18:05 -04:00
Mark DePristo c0bbeb23ba Now providing more information when the index on the fly isn't equal to the one created by reading the file from disk. 2011-07-14 15:12:28 -04:00
Mark DePristo 5ffeddd3b1 better to use _ instead of ., as this is a special case later. 2011-07-14 14:45:16 -04:00
Eric Banks 9540df6998 Oops, forgot to update unit test 2011-07-14 14:00:19 -04:00
Eric Banks ed6beae1f3 Adding headers to diffable reading for VCFs 2011-07-14 13:55:35 -04:00
Eric Banks 66c652d687 Added some extra error checks in the VCF codec. Now that we've moved this back into the GATK, changed some of the standard exceptions to be USerErrors (instead of TribbleExceptions). 2011-07-14 11:56:10 -04:00
Eric Banks 0c54c796ed Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-13 14:57:33 -04:00
Eric Banks bb0e3a26fc Added integration test for VCF writing. Also, bug fix for writing the GT-free records. 2011-07-13 14:57:21 -04:00
Eric Banks 6a431da554 Don't output source and ref header lines anymore. Short-term motivation for this is that I'd like this tool when run on a VCF to emit the exact same VCF. Long-term motivation is that these tags should be output by the VCF writer itself for all tools. 2011-07-13 14:40:01 -04:00
Menachem Fromer 74aa49e423 Merged bug fix from Stable into Unstable 2011-07-13 12:12:42 -04:00
Menachem Fromer fa3ff53508 Filters should only be applied to the new VC if the old VC had filters applied 2011-07-13 11:58:16 -04:00
Eric Banks 969227c657 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-13 10:01:28 -04:00
Eric Banks 797c50e689 Fixing integration tests I broke yesterday; removing batch merging test since we don't support that anymore. 2011-07-13 10:01:23 -04:00
Eric Banks 6007eea3ff Allowing VCF records without GTs in vf4.1 2011-07-13 09:56:08 -04:00
Guillermo del Angel 1e81d521c0 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 20:12:29 -04:00
Ryan Poplin 837fb8f689 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:39:26 -04:00
Ryan Poplin 5077c94d85 Adding MappingQualityUnavailableReadFilter to the SNP and indel CountCovariates 2011-07-12 15:39:07 -04:00
Mark DePristo 01fd6a6949 Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:20:44 -04:00
Mark DePristo ccedd6ff4c Difference is now the general form -- used to be SummarizedDifference. The old Difference class is now a subclass of Difference that includes pointers to specific the master and test DiffElements.
Added a size() function that calculates the number of elements tree from a DiffElement.
2011-07-12 15:20:28 -04:00
Eric Banks a2597e7f00 This commit incorporates several different changes that each pretty much break all the VCF-based integration tests, so I bunched them all together. We now officially emit VCF4.1 files (woo hoo), which means that the VCF headers are now all different (header version is 4.1 plus counts for some of the annotations are 'A' or 'G'). Also, I've added a Read Filter for reads with MQ=255 ('unavailable' in the SAM spec) and have applied this to the UG and the RMS MQ annotation. 2011-07-12 14:11:53 -04:00
Ryan Poplin 329c3d8050 Merged bug fix from Stable into Unstable 2011-07-12 13:55:51 -04:00
Ryan Poplin 73735863b0 Fix for the case of requesting genotype for a sample that doesn't exist in a VariantContext 2011-07-12 13:55:21 -04:00
Guillermo del Angel c4c145afb9 Merged bug fix from Stable into Unstable 2011-07-12 13:44:48 -04:00
Guillermo del Angel cfe43e3971 Bug fix for Genotype given alleles: if we are in INDEL mode ignore SNPs and MNPs instead of emitting an empty site with alleles but no annotations 2011-07-12 13:43:46 -04:00
Guillermo del Angel bfbca8b194 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 12:11:58 -04:00
Mark DePristo 05212aea62 reader now takes an argument for the maximum number of elements to read from the file. 2011-07-12 08:53:19 -04:00
Mark DePristo 8056a3fe89 getElement() now uses O(1) get from hash instead of linear O(n) search. Enables us to read large files easily. 2011-07-12 08:52:31 -04:00
Mark DePristo f313e14e4e Now deletes the dump directory on ant clean
Moving diffengine tests from private to public
2011-07-12 08:50:58 -04:00
Eric Banks d7d15019dd Adding support for other simple header line types (e.g. ALT) and cleaning up the interface a bit. 2011-07-12 01:16:21 -04:00
Eric Banks 400b0d4422 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-11 23:38:57 -04:00
Mark DePristo d5056ad899 Merge branch 'master' into diffit 2011-07-11 23:16:15 -04:00
Mark DePristo 893cc2e103 Making the package public, so there's no dependances from public -> private 2011-07-11 23:15:08 -04:00
Mark DePristo 5e593793af DiffEngine utility function simpleDiffFiles
printSummaryReport now uses GATKReport for nice formating
Moved print formatting arguments into inner class provided to printing functions themselves, not the class
BAMDiffableReader only reads 1000 entries to avoid performance issue.  Work around for BAM files with non-unique names
Uncommented all of the incorrectly commented out CombineVariants integrationtests
BaseTest now uses DiffEngine to provide inline differences to VCF and BAM files
2011-07-11 23:10:27 -04:00
Eric Banks e3748675db Support for VCF 4.1 header counts 2011-07-11 17:40:45 -04:00
Guillermo del Angel f54c2ae3b4 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-11 16:26:27 -04:00
Christopher Hartl d6517adb42 Merge branch 'master' of ssh://chartl@tin.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-11 16:16:37 -04:00
Christopher Hartl 86890c6357 N and K (in binomial probability) got switched in RFA Walker with the last commit. No longer will NaNs be produced.
Added: TableToVCF. Kind of a longer-term project, but there are lots of variant calls available in a weird tabular format. I used this to convert Ju Et Al small indels to VCF. I'll check against the 1000G ASN superpopulation calls to see if we see a good amount of recapitulation, and if so, i'll put them in unvalidated comparisons. Minor chances to the TableCodec and TableFeatures to allow for this (the codec can sometimes drop a column, and the feature now allows you to grab on to its header).
2011-07-11 16:16:15 -04:00
Guillermo del Angel d587856f2d Private feature to input a list of family descriptions from a file and to look for MV's on all of these. Feature can also output a detailed description of the violation into a separate file 2011-07-11 14:17:59 -04:00
Guillermo del Angel 6e7b5e1e7a Merged bug fix from Stable into Unstable
Merge branch 'master' into unstable
2011-07-08 21:19:45 -04:00
Guillermo del Angel 7fbc5987d0 Merge branch 'master' of ssh://delangel@nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/stable 2011-07-08 21:17:32 -04:00
Mark DePristo bd29236684 Merge branch 'master' into diffengine 2011-07-08 14:08:17 -04:00
Guillermo del Angel 224574424e Bug fix: if we're genotyping a very long indel (>100 bp) fail gracefully instead of with an array out of bounds exception 2011-07-08 12:48:49 -04:00
Ryan Poplin 2a4b3ae4a2 Cleaning up / removing most of the monkeying around with annotation values that happens in VariantDataManager 2011-07-08 12:48:33 -04:00
Mark DePristo 8add2a3866 Merge branch 'master' into diffengine 2011-07-08 09:15:54 -04:00
Eric Banks cc143493e3 Merged bug fix from Stable into Unstable 2011-07-07 23:01:24 -04:00
Eric Banks 4cfe0dd857 Test for bad alleles so that we don't generate IndexOutOfBoundsExceptions 2011-07-07 23:01:03 -04:00
Mark DePristo 3d4f0e9dd7 Now supports the case where you have multiple AC values in the info field. 2011-07-07 17:21:15 -04:00
Ryan Poplin 212e9a1a0c Fixing unstable build after stable commit 2011-07-07 15:18:57 -04:00
Ryan Poplin 11d9a0473a Merged bug fix from Stable into Unstable 2011-07-07 15:03:58 -04:00
Ryan Poplin 50111db2b7 Fixing non-determinism in single-threaded VQSR by moving references to cern.Normal over to the static random generator available in GenomeAnalysisEngine 2011-07-07 15:02:48 -04:00
Guillermo del Angel 4d565b0811 Merge branch 'incoming' 2011-07-07 06:21:05 -04:00
Guillermo del Angel 55c8c05060 Merge branch 'master' of ssh://delangel@nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-07 06:18:29 -04:00
Guillermo del Angel 5ab2e83904 a) Cosmetic modifications to IndelType annotation. b) Add ability to select samples from a file in PrintReads, c) fixes to shaped AF random selection in SelectVariants 2011-07-07 06:15:10 -04:00
Mark DePristo ccf34f7e45 (1) Added very useful helper class TestDataProvider to BaseTest that making creating data providers for TestNG far easier
(2) DiffEngine now officially working with with summaries.  Extensive UnitTests all around!
2011-07-06 21:57:22 -04:00
Eric Banks 52f6f9fdcc Merged bug fix from Stable into Unstable 2011-07-06 16:05:48 -04:00
Eric Banks 54121eb082 Catch malformed bams that cause the writer to run in infinite loops 2011-07-06 16:05:08 -04:00
Eric Banks 76a01a7453 Merged bug fix from Stable into Unstable 2011-07-06 12:53:09 -04:00
Eric Banks 14fee4ccbd Patch from Bob to deal with symbolic alleles: these weren't getting padded but they should be. 2011-07-06 12:51:44 -04:00
Ryan Poplin bdef233d4d Merged bug fix from Stable into Unstable 2011-07-06 10:05:02 -04:00
Ryan Poplin e8ed6b7f0f Adding more comments to main VQSR walker. Fixing copyright lines. Bug fix for default paths to now point to public/R/ instead of R/ Bug fix in VQSR for the path to the R scripts not ending in a slash. 2011-07-06 10:01:14 -04:00
Guillermo del Angel 8e8b901d12 Merged bug fix from Stable into Unstable
Merge branch 'master' into unstable
2011-07-06 09:57:55 -04:00
Guillermo del Angel 81a4d18468 Mark several indel-related arguments as @Hidden 2011-07-06 09:56:38 -04:00
Guillermo del Angel 9124c84a7c bug fixes 2011-07-04 21:10:44 -04:00
Guillermo del Angel bb85f232b9 bug fixes 2011-07-04 21:04:49 -04:00
Guillermo del Angel f26ffeaea0 bug fixes 2011-07-04 20:48:45 -04:00
Guillermo del Angel 04df153f47 bug fixes 2011-07-04 20:45:10 -04:00
Guillermo del Angel 7a04872a3f bug fixes 2011-07-04 20:33:59 -04:00
Guillermo del Angel 08bc843d4c SelectVariants can get a table to boost AF when choosing randomly 2011-07-04 20:23:22 -04:00
Guillermo del Angel fac082de64 Report only highest AF and AC in multiallelic records in VariantsToTable or else R can't parse table 2011-07-03 14:32:12 -04:00
Guillermo del Angel abe9480c6d Merge branch 'master' of ssh://delangel@nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-02 21:19:15 -04:00
Ryan Poplin fb315b5f8c Merge branch 'incoming' 2011-07-02 18:10:48 -04:00
Ryan Poplin 41d46059e7 fixing bad format statement 2011-07-02 18:09:17 -04:00
Ryan Poplin 3804afeb8a Merge branch 'incoming' 2011-07-02 17:55:39 -04:00
Ryan Poplin 781c0c33a4 Use the worst X% of calls in addition to the bad training sites list. Don't include the already added calls in the calculation of X% 2011-07-02 17:55:10 -04:00
Ryan Poplin 6b8af6afd8 Merge branch 'master' of ssh://gsa1.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-02 17:15:56 -04:00
Ryan Poplin fdc2ebb321 Adding ability to specify in VQSR a list of bad sites to use when training the negative model. Just add bad=true to the list of rod tags for your bad sites track. 2011-07-02 17:15:13 -04:00
Guillermo del Angel 09af6bbc6c Ugh - backed out experimental code not for public consumption unintendedly committed 2011-07-02 16:58:57 -04:00
Guillermo del Angel c6c0dba040 Merge branch 'master' of ssh://delangel@nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-02 16:45:34 -04:00
Ryan Poplin 4532a84314 Merged bug fix from Stable into Unstable 2011-07-02 10:48:55 -04:00
Ryan Poplin 5faf40b79d Moving AnalyzeAnnotations into the archive because it has outlived its usefulness. 2011-07-02 10:39:53 -04:00
Ryan Poplin 17ff5bb094 Variant records coming out of the VQSR are now annotated with which input annotation was most divergent from the Gaussian mixture model. This gives a general sense for why each variant was removed from the callset. 2011-07-02 09:55:35 -04:00
Khalid Shakir c65e52f88a Merged bug fix from Stable into Unstable 2011-07-01 20:50:56 -04:00
Khalid Shakir b6bc64a0c8 Cleanup of the utils.broad package.
Using Picard IoUtils on sample names.
2011-07-01 20:47:03 -04:00
Eric Banks 0c9105ca22 Minor fix of description 2011-07-01 18:07:35 -04:00
David Roazen d647ea4fdc Long-delayed change to CachingIndexedFastaSequenceFile. Made the cache
non-static to avoid problems when multiple references are used within the same
thread (eg., during integration tests). This should kill the intermittent
IndelRealignerIntegrationTest failures.
2011-07-01 16:04:30 -04:00
Eric Banks 761347b8d5 The VariantContext utility method used by SelectVariants wasn't checking the filter status (unfiltered vs. passing filters) and always returned a VC that was passing filters. This is fixed and the md5 from the VCF Streaming test has been re-updated. 2011-06-30 15:26:09 -04:00
Mauricio Carneiro 867056af51 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/stable 2011-06-30 15:03:18 -04:00
Mark A. DePristo defa3cfe85 Moved around private walkers into appropriate directories in private gatk.walkers. Moved a few public walkers into private qc package, and some private qc walkers into the public directory. Removed several obviously broken and/or unused walkers. 2011-06-30 14:59:58 -04:00
Mauricio Carneiro 2cb1376ed0 VCFStreaming was failing integration tests because now select variants outputs the samples in alphabetical order, instead of random as before. Fixed the MD5. 2011-06-30 14:55:39 -04:00
Eric Banks 804d5f22d5 Reverting previous change, as promised. 2011-06-30 13:18:30 -04:00
Eric Banks 9e234cf5d6 This is a temporary commit for Picard. It will absolutely break integration tests, but I'm going to revert it in 1 minute. Because we don't want them in unstable, I need to push this into stable. 2011-06-30 13:17:14 -04:00
Eric Banks 352c38fc0b Updated to reflect dbsnp conversion fix 2011-06-30 11:55:56 -04:00