df2a7039cb
Henious bug fixed: only rookies forget that external conditions need to be re-checked after loop ends on some other condition, duh! In addition, msa piles are now seeded with a single read sequence each (if there are less then 4 reads it might be hard to seed with two pairs)
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@129 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-21 18:32:18 +00:00
411e5cf647
Added FourBaseCaller as a jar build target.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@128 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-21 17:59:13 +00:00
6e1fa7d61a
Java version of basecaller that estimates probability distribution over four-base hypothesis space via an internal-control-initialized Gaussian mixture model over base channel intensities.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@127 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-21 17:58:50 +00:00
3e350006e0
Added a directory to house some Illumina output parsers. Hopefully this will be merged back into Picard at some point.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@126 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-21 17:55:56 +00:00
497eea2e5c
minor changes and shuffling code around; also, now when realigned piles are printed they are sorted by start position
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@125 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-21 17:43:49 +00:00
0ea44a5805
1st draft of support for an file containing a list of intervals.
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Appears to work, but inefficient:
At each reference location, the entire list of intervals is linear searched.
Instead we need to have the intervals sorted, and simply seek forward from interval to interval.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@124 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-21 16:07:32 +00:00
1fcf4c0cbf
Update picard to work with new samtools.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@123 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 21:51:26 +00:00
5dca560c3c
A bunch of refactoring, and more on the way.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@122 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 21:31:07 +00:00
b806a9cf68
Updated for new version of samtools, which returns a sequence dictionary
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rather than a simple list of sequences.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@121 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 20:38:24 +00:00
6e2d939905
Added subversion rev 180 of the sam library.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@120 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 20:17:51 +00:00
c5433a3120
dumps out base qualities per position for use in making boxplots
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@119 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 17:01:18 +00:00
1161c261ac
made all data members public.
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switched logOddsVarRef to LOD.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@118 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 16:44:17 +00:00
9b5e5e06f9
Now supports checking that the input files exist and are good
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@117 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 16:40:54 +00:00
f3f1b47808
deal with reverse complemented reads
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@115 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 16:01:49 +00:00
9ec96414c7
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@114 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 15:54:29 +00:00
322f4b944f
Better stress test
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@113 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 15:52:54 +00:00
3565b50ff5
main class (argument processing and traversing the reference) and implementation of all the Receiver functionality for building read piles over indels
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@112 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 05:18:04 +00:00
4c3b92b860
comparator for interval objects
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@111 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 05:15:13 +00:00
f810412d75
equals(), hashCode() updated/added, also a few minor changes
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@110 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 05:13:07 +00:00
4badd54216
Indel also implements Interval interface but has its quirks
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@109 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 05:11:17 +00:00
501e92d441
an interface for an interval object and simple minimum implementation; note: in contrast to arachne, this is closed interval
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@108 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 05:09:56 +00:00
29d2d460f3
a trivial interface and even more trivial implementations that do nothing (ignore the data they receive)
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@107 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 05:08:15 +00:00
b83c8319c7
Crushed subtle and potentially insidous bug in seeking within the fasta; a beer for anyone who can tell me the situation where this might arise...
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@106 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-20 00:07:06 +00:00
34ee48fd82
Fixing output printing issues in the code, as well as adding more safety checks
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@105 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 23:02:49 +00:00
6fdd622160
Describe how GATK finds walkers. Change the example to avoid copying the class file into the walkers directory.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@104 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 22:41:12 +00:00
104e2811ec
Configure the plugin directory.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@103 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 22:12:25 +00:00
6bcdac5c62
Restructured AlleleFrequency classes into 3 classes: AlleleFrequencyWalker, AlleleFrequencyMetricsWalker, AlleleFrequencyEstimate. AlleleFrequencyMetricsWalker class now calls mapper function of AlleleFrequencyWalker and works with the result. AlleleFrequencyEstimate is now a separate class instead of a subclass of AlleleFrequencyWalker.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@102 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 22:06:01 +00:00
41fec1565c
Hello, world! for GATK.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@101 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 21:46:22 +00:00
7bc45b68aa
Added dependences on two libraries: the Colt package, which is a collection of high performance computing libraries from CERN; and Log4j, which will be our new logging platform.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@100 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 16:16:31 +00:00
5fa99f430e
One line format is useable and two levels of debug output are available (debug = 1: one line format, debug = 2: table of sampled probs for each locus). Class AlleleFrequencyMetrics computes %dbSNP and frequency of SNPs.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@99 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 15:05:05 +00:00
f1034f3dfd
Stress Test utility for pushing the GATK to its limits. Takes a list of sam files and runs Analyses on them all, optionally in the queue
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@98 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-19 03:15:00 +00:00
4242dba295
Remove endless iterator.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@97 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 23:53:40 +00:00
225ea64bd9
Moved extra walkers at Mark's request.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@96 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 23:52:08 +00:00
ffb6f8f5da
Move the basic gatk framework into the core subtree.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@95 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 23:39:00 +00:00
69316f1873
removed unused import statement
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@94 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 21:56:15 +00:00
875272e5c5
moved counted object to utils
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@93 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 21:54:04 +00:00
e09af2ef70
changed variable declaration from concrete class to interface
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@92 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 21:50:47 +00:00
708ada3e99
an accessory for CountedObject: builds a comparator for CountedObject<T> given a comparator for T; compares the underlying objects T themselves, *not* the associated counters
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@91 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 21:45:54 +00:00
37101045af
a simple wrapper class; less overhead than keeping a separate Integer counter object and going through object reallocation and/or autoboxing on each counter increment
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@90 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 21:44:30 +00:00
45d2a9acd8
Added walker to print out a histogram of where mismatches occur in alignments
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@89 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 19:46:42 +00:00
1096bbd4d9
Moved build.xml, ivy.xml and settings to root of Sting repository.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@88 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 19:13:19 +00:00
d46ee96269
Added support for loose Walker class files in walkers directory.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@87 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 17:32:24 +00:00
fe9e52c47e
allow on fly sorting AND validation
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@86 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-18 15:50:17 +00:00
bb94c853f8
Added WalkerManager -- a class that dynamically loads available walkers
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from the jar file. For now, added placeholder Walker interface so that
WalkerManager could work with classes of type Walker rather than classes
of type Object.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@85 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 23:22:37 +00:00
d9fa04f65c
Fixed logic
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@84 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 22:20:03 +00:00
1aa3958644
Added ability to sort reads on the fly
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@83 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 20:29:09 +00:00
0362cb9e59
added Utils.filterInPlace() - purges elements directly from the passed collection object without creating new list for results
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@82 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 19:06:40 +00:00
58aa2aab43
Rough draft of patch to use bam indices when available.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@81 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 16:39:03 +00:00
151c37591e
removed unnecessary import that produced a warning. where did it come from in the first place??
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@80 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 15:46:27 +00:00
478425b3d8
Better error messages
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@79 348d0f76-0448-11de-a6fe-93d51630548a
2009-03-17 15:37:02 +00:00
asivache
kiran
jmaguire
hanna
ebanks
depristo
andrewk
aaron