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12 Commits (dee130ad1b042d604a3ff9e6453203402f1dfd3f)

Author SHA1 Message Date
carneiro c61dd2f09f data processing pipeline now has on the fly bam indexing (powered by Matt) some new parameters, Indel Cleaning with constrain movement and fixMates is gone. 
setting up methods development pipeline for some cosmetic changes.


git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5277 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-18 23:13:54 +00:00
depristo d97ed3e080 Comments for Mauricio 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5275 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-18 16:58:34 +00:00
carneiro acad3ada06 changed baq to calculate_as_necessary. 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5270 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-17 23:50:46 +00:00
carneiro 7f9ca6b28a full data processing pipeline, now deleting intermediate files and performing both phases (per lane and combined) of the processing. 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5269 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-17 23:34:00 +00:00
carneiro 497e9ab83b too hasty... cleaning up debug messages ;) 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5257 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-17 02:11:03 +00:00
carneiro b4da843c49 now processes either a single bam file or a list of bam files in parallel. 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5256 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-17 02:07:22 +00:00
carneiro 50c870cfce Data Processing Pipeline: local indel realignment, mark duplicates and BQSR. Done. 
Pacbio pipeline: now all pacbio bams have baq annotated in so running UG is uber fast.

Methods pipeline: minor cosmetic changes.



git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5253 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-16 17:22:30 +00:00
carneiro 6d3b878dde data processing pipeline script already does: 
. Local Indel Realignment 
. Mark Duplicates

will do:
. Base Quality Score Recalibration (soon)

it's working with a single BAM for testing, but will work with a list of bam files.



git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5250 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-15 21:49:05 +00:00
carneiro 87e19a17ae small updates to the variant eval part of the pipeline, some updates to the pacbio specific pipeline. 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5244 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-15 16:19:07 +00:00
carneiro 5f10fffa47 merge intervals now prints a sorted list in the end. 
added the ccs datasets to the pbCalling pipeline.

git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5233 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-11 20:57:59 +00:00
carneiro 50c2fa3c3a this -1 made ALL the difference in the world. Minor bug fix. 
Regular updates to the pbCalling pipeline.

git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5232 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-11 19:25:09 +00:00
carneiro 9c2c5efe35 a modified version of the Methods Development calling pipeline made to work with pacbio data. 
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@5225 348d0f76-0448-11de-a6fe-93d51630548a
 2011-02-10 16:06:50 +00:00