Commit Graph

3212 Commits (d4b4f95e122ced649ff49a989c63e36a3ef3fc46)

Author SHA1 Message Date
Ami Levy-Moonshine d4b4f95e12 move CatVariants to public 2013-01-07 15:07:16 -05:00
Eric Banks b4e7b3d691 Fixed precision problem in the Bayesian calculation of Qemp: we need to cap below max integer because the MathUtils code add +1.
Added unit tests for handling large number of observations.
2013-01-07 13:07:36 -05:00
Tad Jordan 04e3978b04 Fixed VariantEval tests
-Added sorting by rows to VariantEval
2013-01-07 12:45:32 -05:00
Ryan Poplin 4f95f850b3 Bug fix in the HC's allele mapping for multi-allelic events. Using the allele alone as a key isn't sufficient because alleles change when the reference allele changes during VariantContextUtils.simpleMerge for multi-allelic events. 2013-01-07 11:05:44 -05:00
Ami Levy-Moonshine d3c2c97fb2 Merge branch 'master' of github.com:broadinstitute/gsa-unstable 2013-01-06 23:35:47 -05:00
Ami Levy-Moonshine c554d9db25 add TODO 2013-01-06 23:04:38 -05:00
Ami Levy-Moonshine 81eef3aa37 merge development branchs of log-less HMM and FastGatherer to master 2013-01-06 23:01:58 -05:00
Eric Banks 0249e1f497 Resolving merge conflicts from VCF move 2013-01-06 14:32:31 -05:00
Eric Banks 8822b8e7c8 Moving HelpConstants out of HelpUtils so that we stop getting these ProgramElementDoc errors when com.sun.javadoc cannot load on a user's system. 2013-01-06 14:30:45 -05:00
Eric Banks ef638489d5 Fixing BQSR gatherer test to keep up to date with latest changes 2013-01-06 14:07:59 -05:00
Eric Banks ea21dc9cfb I just committed this - why didn't it work before? Trying again... 2013-01-06 12:44:13 -05:00
Eric Banks 52067f0549 Handle merge conflicts 2013-01-06 12:29:12 -05:00
Eric Banks bf25e151ff Handle long->int precision in Bayesian estimate 2013-01-06 12:26:32 -05:00
Eric Banks b73d72fe94 update docs for LEftAlignVariants 2013-01-06 01:56:57 -05:00
Mark DePristo b403c269e9 Make multi-threaded progress meter daemon unit test more robust 2013-01-05 12:59:18 -05:00
Mark DePristo 2ab55e4ee7 Fixing bug in TraverseDuplicates.printProgress call: only passes in single location of genome loc 2013-01-05 12:50:27 -05:00
Mark DePristo 69bf70c42e Cleanup and more unit tests for RecalibrationTables in BQSR
-- Added unit tests for combining RecalibrationTables.  As a side effect now has serious tests for incrementDatumOrPutIfNecessary
-- Removed unnecessary enum.index system from RecalibrationTables.
-- Moved what were really static utility methods out of RecalibrationEngine and into RecalUtils.
2013-01-05 12:50:27 -05:00
Chris Hartl 9df30880cb Merge branch 'master' of github.com:broadinstitute/gsa-unstable 2013-01-04 17:15:22 -05:00
Joel Thibault 01738e70c3 Archive the experimental Active Region Traversals 2013-01-04 17:05:31 -05:00
Chris Hartl 7b7efa0fff Add in the AAL as an experimental covariate, in case it's wanted. 2013-01-04 16:47:26 -05:00
Chris Hartl 41bc416b65 Remove AAL and update MD5s. 2013-01-04 16:46:14 -05:00
Eric Banks bce6fce58d Resolving merge conflicts after Mark's latest push 2013-01-04 14:46:39 -05:00
Eric Banks dd7f5e2be7 Hooking up the Bayesian estimate code for calculating Qemp in BQSR; various fixes after adding unit tests. 2013-01-04 14:43:11 -05:00
Ami Levy-Moonshine 80b531f695 emit all sites where more than 90% of the samples have good coverage 2013-01-04 14:27:50 -05:00
Joel Thibault ab5526b372 More TODOs 2013-01-04 14:09:02 -05:00
Tad Jordan fe06912a87 Removed sorting by row from walkers 2013-01-04 11:52:33 -05:00
Mark DePristo 810e2da1d4 Cleanup and unit tests for EventType and ReadRecalibrationInfo in BQSR
-- Added unit tests for EventType and ReadRecalibrationInfo
-- Simplified interface of EventType.  Previously this enum carried an index with it, but this is redundant with the enum.ordinal function.  Now just using that function instead.
2013-01-04 11:39:25 -05:00
Mark DePristo a5901cdd20 Bugfix for printProgress in TraverseReadsNano
-- Must provide a single bp position (1:10) not the range of the read (1:1-50).  ProgressMeter now checks at runtime for this problem as well.
2013-01-04 11:39:24 -05:00
Mark DePristo bbdf9ee91b BQSR cleanup: merge Advanced and Standard recalibration engine into just the RecalibrationEngine
-- As we are no longer maintaining a public/protected system we need only have one RecalibrationEngine.
-- Misc. code cleanup and docs along the way
2013-01-04 11:39:24 -05:00
Mark DePristo 7df47418d8 BQSR optimization: make RecalibrationTables thread-local, and merge results in onTraversalDone
-- With the newer, faster BQSR, scaling was limited by the NestedIntegerArray.  The solution to this is to make the entire table thread-local, so that each nct thread has its own data and doesn't have any collisions.
-- Removed the previous partial solution of having a thread-local quality score table
-- Added a new argument -lowMemory
2013-01-04 11:39:24 -05:00
Mark DePristo 1ba8d47a81 Unit tests for ProgressMeterDaemon 2013-01-04 11:39:24 -05:00
Mark DePristo fbee4c11f1 Unit tests for ProgressMeterData 2013-01-04 11:39:23 -05:00
Joel Thibault 319d651e4a Initial updates for ActiveRegionShard 2013-01-03 17:00:13 -05:00
Joel Thibault e7553545ef Initial updates for ReadShard 2013-01-03 17:00:13 -05:00
Joel Thibault 14a3ac0e3c Enable the use of alternate shards 2013-01-03 17:00:13 -05:00
Joel Thibault 4cc372f53b LocusShardDataProvider doesn't need its own GenomeLocParser 2013-01-03 17:00:13 -05:00
Joel Thibault ffbd4d85f2 No need to pass fields as parameters 2013-01-03 17:00:12 -05:00
Joel Thibault 47e620dfbc Create BAM index to test shard boundaries 2013-01-03 17:00:12 -05:00
Tad Jordan c1ba12d71a Added unit test for outputting sorted GATKReport Tables
- Made few small modifications to code
- Replaced the two arguments in GATKReportTable constructor with an enum used to specify way of sorting the table
2013-01-03 16:53:59 -05:00
Ami Levy-Moonshine 10a705b27f Merge branch 'master' of github.com:broadinstitute/gsa-unstable 2013-01-03 13:42:31 -05:00
Ami Levy-Moonshine 2018285a39 better error message 2013-01-03 13:41:03 -05:00
Eric Banks c7039a9b71 Pushing in implementation of the Bayesian estimate of Qemp for the BQSR.
This isn't hooked up yet with BQSR; it's just a static method used in my testing walker.  I'll hook this into BQSR after more testing and the addition of unit tests.
Most of the changes in this commit are actually documentation-related.
2013-01-02 15:21:44 -05:00
Joel Thibault c515175313 Ensure that active region extensions stay on contig 2013-01-02 14:46:24 -05:00
Joel Thibault dcb7735d3c Active Region extensions must stay on contig 2013-01-02 14:46:24 -05:00
Chris Hartl 09199366b7 Merge branch 'master' of github.com:broadinstitute/gsa-unstable 2013-01-02 14:44:49 -05:00
Chris Hartl e1d09ab0db QD is now divided by the average length of the alternate allele (weighted by the allele count). The average length is stored in a related annotation, "AAL", which can be used to re-compute the "old" QD by simple multiplication. Integration tests *should* all pass. 2013-01-02 14:41:29 -05:00
Joel Thibault a15f368bdc Re-enable testIsActiveRangeLow/High 2013-01-02 11:57:50 -05:00
Mark DePristo 12f4c6307e AutoFormattingTime cleanup and complete unittests
-- Underlying system now uses long nano times to be more consistent with standard java practice
-- Updated a few places in the code that were converting from nanoseconds to double seconds to use the new nanoseconds interface directly
-- Bringing us to 100% test coverage with clover with AutoFormattingTimeUnitTest
2013-01-02 11:29:25 -05:00
Joel Thibault 429567cd3f Rename to TraverseActiveRegionsUnitTest 2013-01-01 19:20:30 -05:00
Joel Thibault 57d38aac8a Temporarily disable due to unknown contracts problem 2013-01-01 19:20:04 -05:00