Commit Graph

4 Commits (c64bf80b57beefe09ad11cd78f4e86f7d5902de6)

Author SHA1 Message Date
chartl 0944184832 Major refactoring of library and full calling pipeline (v2) structure.
Arguments to the full calling qscript (and indeed, any qscript that wants them) are now specified via the PipelineArgumentCollection

Libraries require a Pipeline object for instantiation -- eliminating their previous dependence on yaml files

Functions added to PipelineUtils to build out the proper Pipeline object from the PipelineArgumentCollection, which now contains 
additional arguments to specify pipeline properties (name, ref, bams, dbsnp, interval list); which are mutually exclusive with
the yaml file.

Pipeline length reduced to a mere 62 lines.




git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@4790 348d0f76-0448-11de-a6fe-93d51630548a
2010-12-05 02:33:54 +00:00
chartl 9f03f09cc9 Changes to V2 pipeline and libraries. AB dropped. Cleaning enabled. Project name now properly propagated to intermediate files (instead of the string repr of the object). Indel mask is now expanded prior to filtering at indels.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@4769 348d0f76-0448-11de-a6fe-93d51630548a
2010-12-01 18:55:48 +00:00
chartl 06a0fb4489 Library-ized pipeline now functions
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@4759 348d0f76-0448-11de-a6fe-93d51630548a
2010-11-30 21:34:59 +00:00
chartl 21ec44339d Somewhat major update. Changes:
- ProduceBeagleInputWalker
 + Now takes a validation ROD and a prior to give it, will use those genotypes in place of the variant genotypes if both are present
 + Takes a bootstrap argument -- can use some given %age of the validation sites
 + Optionally takes a bootstrap output argument -- re-prints the validation VCF, filtering those sites used as part of the bootstrap
-BeagleOutputToVCFWalker
 + Now filters sites where the genotypes have been reverted to hom ref
 + Now calls in to the new VCUtils to calculate AC/AN

-Queue
 + New pipeline libraries for easy qscript creation, still a work in progress, but this is a considerable prototype
 + full calling pipeline v2 uses the above libraries
 + minor changes to some of my own scripts
 + no more need for contig interval lists, these will be parsed out of your normal interval list when it is provided



git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@4459 348d0f76-0448-11de-a6fe-93d51630548a
2010-10-08 13:30:28 +00:00