Commit Graph

21 Commits (c191103326d2f515a4ec08033eb4d0463affafdb)

Author SHA1 Message Date
Eric Banks 2df2a153e6 Merge pull request #658 from broadinstitute/ldg_PbyTwithPriors
Updated CalculateGenotypePosteriors to compute genotype posteriors using...
2014-06-18 15:04:39 -04:00
Laura Gauthier 2356d5d63f Updated CalculateGenotypePosteriors to compute genotype posteriors using likelihoods from all members of the trio.
(Right now it only works if all members of the trio are called.)
Takes posteriors as input, defaulting to PLs
Added annotations for possible de novos for us in full genotype refinement pipeline
Added family priors to CGP integration test.
Changed CGP to use PP tag instead of GP tag because posteriors are Phred-scaled. Updated CGP integration test md5s to reflect change.
2014-06-18 11:17:15 -04:00
Phillip Dexheimer 2e78815055 Added missing arguments to GenotypeGVCFs
- New arguments are nda, hets, indelHeterozygosity, stand_call_conf, stand_emit_conf, ploidy, and maxAltAlleles
 - Addresses PT 70110918
 - To do this, moved those arguments out of the StandardCallerArgumentCollection into a new GenotypeCalculationArgumentCollection, which is now included as a member of SCAC
2014-06-16 08:10:54 -04:00
Valentin Ruano Rubio db96891d4b Merge pull request #638 from broadinstitute/vrr_createTempFile_testfix
Changed File.createTempFile to BaseTest.createTempFile calls Test
2014-05-29 10:15:05 -04:00
Valentin Ruano-Rubio 07567fdae3 Removed debug code outputing files not removed after VM exists in ReadThreadingLikelihoodCalculationEngineUnitTest.
Notice however that this should not be the cause of resent problems as the code was desactivated.
2014-05-28 19:03:25 -04:00
Valentin Ruano-Rubio e0c221470c Changed File.createTempFile to BaseTest.createTempFile 2014-05-28 18:59:48 -04:00
EvolvedMicrobe ef7531d4a5 Merge pull request #640 from broadinstitute/IntegerSWImplementation
Change SmithWaterman to use integers instead of doubles.
2014-05-28 15:10:05 -04:00
Nigel Delaney cc45e62e8e Change SmithWaterman to use integers instead of doubles. 2014-05-28 13:13:14 -04:00
Phillip Dexheimer c15e6fcc0e Refactored the static lookup arrays in MathUtils (log10Cache, log10FactorialCache, jacobianLogTable)
-They are now only computed when necessary
 -Log10Cache is dynamically resizable, either by calling get() on an out-of-range value or by calling ensureCacheContains
 -Log10FactorialCache and JacobianLogTable are initialized to a fixed size on first access and are not resizable
 -Addresses PT 69124396
2014-05-27 22:27:57 -04:00
Eric Banks b77589696e Merge pull request #643 from broadinstitute/rp_remove_hwp
Removing HWP from GenotypeSummaries because of integer overflow issues w...
2014-05-27 17:21:19 -04:00
David Roazen 74b51c5c7a Improve test suite tmp file cleanup
-Make BaseTest.createTempFile() mark any possible corresponding index files for deletion on exit

-Make WalkerTest mark shadow BCF files and auxiliary for deletion on exit

-Make VariantRecalibrationWalkersIntegrationTest mark PDF files for deletion on exit
2014-05-27 13:41:44 -04:00
Ryan Poplin b24cff780b Removing HWP from GenotypeSummaries because of integer overflow issues with 91K samples. Removing CCC because it is redundant. 2014-05-27 10:14:49 -04:00
Ryan Poplin ec7c4ea2ba Unfortunately dangling tail recovery is dangerous in exome data. Turning it off by default for now.
-- disabling HC+VA integration test because, as noted in the comments, it keeps switching PairHMM implementations and giving different results at a particular site used in that particular test
2014-05-23 14:33:44 -04:00
Valentin Ruano-Rubio 979ab0453e Moved GlobalEdgeGreedySWPairwiseAlignment to the archive 2014-05-23 01:48:48 -04:00
Valentin Ruano-Rubio 7c8a1ae892 Fix for SW to make double comparisons with a tolerance
Stories:

  - https://www.pivotaltracker.com/story/show/69577868

Changes:

  - Added a epsilon difference tolerance in weight comparisons.

Tests:

  - Added HaplotypeCallerIntegrationTest#testDifferentIndelLocationsDueToSWExactDoubleComparisonsFix
  - Updated md5 due to minor likelihood changes.
  - Disabled a test for PathUtils.calculateCigar since does not work and is unclear what is causing the error (needs original author input)
2014-05-23 01:48:48 -04:00
Ryan Poplin 581843d994 Minor updates to HC docs. 2014-05-20 10:01:11 -04:00
Khalid Shakir 88d7e23c44 After talking with Mauricio and Karthik, updated MD5s and added a note about PairHMM causing test variability. 2014-05-19 17:36:41 -04:00
Karthik Gururaj 972a82d386 Changed 'sting' to 'gatk' in the VectorLoglessPairHMM classes and the
C++ code
2014-05-19 17:36:41 -04:00
Khalid Shakir 3939971d78 After renaming the packages, instead of updating the JNI library used for testing bwa, moving the classes to the archive.
NOTE: The migrated READEME.md has been added that will allow others to possibly ressurect this code as needed.
2014-05-19 17:36:41 -04:00
Khalid Shakir 2c854e554a Refactored maven directories and java packages replacing "sting" with "gatk".
To reduce merge conflicts, this commit modifies contents of files, while file renamings are in previous commit.
See previous commit message for list of changes.
2014-05-19 17:36:39 -04:00
Khalid Shakir 4e6d43d003 Refactored maven directories and java packages replacing "sting" with "gatk".
To reduce merge conflicts, this commit only renames files, while file modifications are in next commit.
Some updates/fixes here are actually included in the next commit.
= Maven updates
Moved artifacts to new package names:
* private/queue-private -> private/gatk-queue-private
* private/gatk-private -> private/gatk-tools-private
* public/gatk-package -> protected/gatk-package-distribution
* public/queue-package -> protected/gatk-queue-package-distribution
* protected/gatk-protected -> protected/gatk-tools-protected
* public/queue-framework -> public/gatk-queue
* public/gatk-framework -> public/gatk-tools-public
New poms for new artifacts and packages:
* private/gatk-package-internal
* private/gatk-queue-package-internal
* private/gatk-queue-extensions-internal
* protected/gatk-queue-extensions-distribution
* public/gatk-engine
Updated references to StingText.properties to GATKText.properties.
Updated ant-bridge.sh to use gatk.* properties instead of sting.*.
= Engine updates
Renaming files containing engine parts from o.b.gatk.tools to o.b.gatk.engine.
Changed package references from tools to engine for CommandLineGATK, GenomeAnalysisEngine, ReadMetrics, ReadProperties, and WalkerManager.
Changed package reference tools.phonehome to engine.phonehome.
Renamed classes *Sting* to *GATK*, such as ReviewedGATKException.
= Test updates
Moved gatk example resources.
Moved test engine files from tools to engine packages.
Moved resources for phonehome to proper package.
Moved test classes under o.b.gatk into packages:
* o.b.g.utils.{BaseTest,ExampleToCopyUnitTest,GATKTextReporter,MD5DB,MD5Mismatch,TestNGTestTransformer}
* o.b.g.engine.walkers.WalkerTest
Updated package names in DependencyAnalyzerOutputLoaderUnitTest's data.
= Queue updates
Moving queue scripts to location where generated extensions can be used.
Renamed *.q to *.scala, updating licenses previously missed by git hooks.
Moved queue extensions to new artifact gatk-queue-extensions.
Fixed import statments frequently merge-conflicting on FullProcessingPipeline.scala.
= BWA
Added README on how to obtain and include bwa as a library.
Updated libbwa build.
Fixed packaged names under bwa/java implementation.
Updated contents of BWCAligner native implementation.
= Other fixes
Don't duplicate the resource bundle entries by both unpacking *and* appending.
(partial fix) Staged engine and utils poms to build GATKText.properties, once Utils random generator dependency on GATK engine is fixed.
Re-enabled custom testng listeners/reporters and moved testng dependencies to the gatk-root.
Updated comments referencing Sting with GATK.
Moved a couple untangled classes from gatk-tools-public to gatk-utils and gatk-engine.
2014-05-19 16:43:47 -04:00