Commit Graph

563 Commits (beb947d3cc979a7bf46e41b33456bce9b9d786ef)

Author SHA1 Message Date
Mark DePristo e37a638e09 Fix for disallowed characters in GATKReportTable
-- Illegal characters are automatically replaced with _
2011-08-26 13:24:06 -04:00
Mark DePristo c0503283df Spelling fix requires md5 updates 2011-08-26 07:40:44 -04:00
Mark DePristo eef1ac415a Merge branch 'master' into rodTesting
Conflicts:
	public/java/src/org/broadinstitute/sting/gatk/walkers/variantutils/VariantsToTable.java
2011-08-26 00:35:41 -04:00
Eric Banks 9b7512fd94 Just because there's a ref base doesn't mean the VC needs to be padded 2011-08-25 22:42:14 -04:00
Mark DePristo e01273ca7c Queue now writes out queueJobReport.pdf
-- General purpose RScript executor in java (please use when invoking RScripts)
-- Removed groupName.  This is now analysisName
-- Explicitly added capability to enable/disable individual QFunction
2011-08-25 16:57:11 -04:00
Eric Banks 09a729da3a Removing incorrect comment 2011-08-25 15:42:52 -04:00
Eric Banks 8bbef79fc2 Create clipped alleles during allele parsing instead of creating a full VC, clipping alleles, and regenerating the VC from scratch. 2011-08-25 15:37:26 -04:00
Ryan Poplin 29c7b10f7b Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-24 15:18:58 -04:00
Ryan Poplin e5008aba00 Output the top two haplotypes as a variant call by running smith-waterman alignment against the reference and calling any difference as variation. This is the first verion that runs end-to-end by taking in reads as bam file and writing out variant calls in VCF. 2011-08-24 15:18:44 -04:00
Guillermo del Angel e618cb1e79 a) Renamed/expanded SelectVariants arguments that choose particular kinds of variants and particular allelic types, now instead of -Indels or -SNPs we can specify for example -selectType [MIXED|INDEL|SNP|MNP|SYMBOLIC]. To select biallelic, multiallelic variants, use -restrictAllelesTo [BIALLELIC|MULTIALLELIC]. Corresponding gatkdocs changes.
b) More useful AC,AF logging in VariantsToTable with multiallelic sites: instead of logging comma-separated values, log max value by default. Hidden, experimental argument -logACSum to log sum of ACs instead. This is due to extreme slowness of R in parsing strings to tokens and computing max/sum itself (~100x slower than gatk).
c) Added integrationtest for new SelectVariants commands
2011-08-24 12:25:50 -04:00
Mark DePristo 28ee6dac41 Fixed spelling mistake 2011-08-24 10:14:45 -04:00
Ryan Poplin f37875600a Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-24 09:02:44 -04:00
Khalid Shakir 1ecbf05aae Avoid segfaults due to out of date and possibly abandonded LSF DRMAA implementation when use'ing LSF instead of .combined_LSF_SGE 2011-08-23 23:49:36 -04:00
Mark DePristo 569e1a1089 Walker.isDone() aborts execution early
-- Useful if you want to have a parameter like MAX_RECORDS that wants the walker to stop after some number of map calls without having to resort to the old System.exit() call directly.
2011-08-23 16:53:06 -04:00
Ryan Poplin a1a1fac9e4 Likelihood engine now gives non-zero likelihoods. Using HMM function that can handle context specific gap open and gap continuation penalties 2011-08-23 13:43:07 -04:00
Guillermo del Angel 6e2552a9ef Merge fix 2011-08-23 12:40:43 -04:00
Guillermo del Angel 8b7a0b3b62 Two new arguments to SelectVariants to exclude either multiallelic or biallelic sites from input vcf 2011-08-23 12:40:01 -04:00
Mark DePristo 6d6feb5540 Better error message when you cannot determine a ROD type because the file doesn't exist or cannot be read 2011-08-23 10:56:37 -04:00
Mauricio Carneiro feeab6075f Merging ReduceReads development with unstable repo
It is time to bring the ReadClipper class to the main repo. Read Clipper has tested functionality for soft and hard clipping reads. I will prepare thorough documentation for it as it will be very useful for the assembler and the GATK in general.
2011-08-22 23:03:03 -04:00
Guillermo del Angel ee68713267 Further Bug fixes to CountVariants: stratifications were wrong in case genotypes had no-calls, for example if we stratified by sample and a sample had a no-call, this no-call was considered a true variant and counts were incorrectly increased 2011-08-22 20:42:47 -04:00
Guillermo del Angel c270384b2e Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-22 20:39:32 -04:00
Guillermo del Angel 8ae24912f4 a) Misc fixes in Phase1 indel vqsr script,
b) More R-friendly VariantsToTable printing of AC in case of multiple alt alleles
c) Rename FixPLOrderingWalker to FixGenotypesWalker and rewrote: no longer need older code, replaced with code to replace genotypes with all-zero PL's with a no-call.
2011-08-22 20:39:06 -04:00
Mark DePristo 85c5a6f890 Merge branch 'rodTesting'
Conflicts:
	private/java/src/org/broadinstitute/sting/gatk/walkers/performance/ProfileRodSystem.java
2011-08-22 17:43:47 -04:00
Mark DePristo 1eab9be35d Now with accurate javadoc 2011-08-22 17:25:15 -04:00
Mark DePristo 3612a3501d info, not warn, about dynamic type determination 2011-08-22 17:24:51 -04:00
Eric Banks dc42571dd9 Only create the genotype map when necessary 2011-08-22 15:40:36 -04:00
Khalid Shakir c4c90c8826 Updates to JobRunners from the Queue developer community and from running the WholeGenomePipeline:
- Ability to pass a different resident memory reservation and limits. Useful for large pileups of low pass genome data that sometimes need high -Xmx6g but usually don't exceed 2-3g in actual heap size.
- Fixed jobPriority to work for all job runners. Now must be a integer between 0 and 100- even for GridEngine- and will be mapped to the correct values.
- Passing parallel environment and job resource requests to LSF and GridEngine. Useful for passing tokens like iodine_io=1 and -pe pe_slots 8
- Refactored GridEngine JobRunner to also provide basic support for other job dispatchers with DRMAA implementations such as Torque/PBS. Should work for basic running but advanced users must pass their own jobNativeArgs from the command line or in customized QScripts until someone maps properties like jobQueue, jobPriority, residentRequest, etc. into a Torque/PBS/etc. dispatcher.
2011-08-22 15:13:27 -04:00
Eric Banks 2c24b68a96 Working implementation of DecodeLoc for VCF parsing. Makes indexing 3x faster. 2011-08-22 15:11:21 -04:00
Eric Banks 518b3dd291 Don't let the genotypes map be null 2011-08-22 15:10:30 -04:00
Ryan Poplin f93a554b01 updating exome specific parameters in MDCP 2011-08-21 10:25:36 -04:00
Ryan Poplin dbff84c54e Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-21 10:09:19 -04:00
Khalid Shakir 22ca44c015 Fixed Queue's tagging of RodBindings.
Fixed argument definition names.
2011-08-21 02:34:20 -04:00
Eric Banks a8cbced71b Bug fix for Ryan: check for no context 2011-08-20 22:49:51 -04:00
Eric Banks 0ccd173967 Fixing the recent SelectVariants fix 2011-08-20 21:30:08 -04:00
Ryan Poplin b008676878 fixing the previous fix 2011-08-20 21:21:55 -04:00
Guillermo del Angel 782453235a Updated VariantEvalIntegrationTest since there's a new column separating nMixed and nComplex in CountVariants
Misc updates to WholeGenomeIndelCalling.scala
Bug fix in VariantEval (may be temporary, need more investigation): if -disc option is used in sites-only vcf's then a null pointer exception is produced, caused by recent introduction of -xl_sf options.
2011-08-20 12:24:22 -04:00
Ryan Poplin 539e157ecd Fixing misc parameters in MDCP. The pipeline now does VariantEval of output by default. Fix for NaN vqslod values in VQSR 2011-08-20 11:28:48 -04:00
Guillermo del Angel 4939648fd4 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-20 08:50:43 -04:00
Ryan Poplin a96ecbab71 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-19 19:30:05 -04:00
Ryan Poplin ddb5045e14 Updating the methods development calling pipeline for the new rod binding syntax and the new best practices. 2011-08-19 19:29:51 -04:00
Mark DePristo ff018c7964 Swapped argument order but not MD5 order 2011-08-19 16:55:56 -04:00
Mark DePristo 8b3cfb2f1c Final documented version of GATKDoclet and associated classes
-- Docs on everything.
-- Feature complete.  At this point only minor improvements and bugfixes are anticipated
2011-08-19 16:52:17 -04:00
Mark DePristo b08d63a6b8 Documentation and code cleanup for ClipReads, CallableLoci, and VariantsToTable
-- Swapped -o [summary] and -ob [bam] for more standard -o [bam] and -os [summary] arguments.
-- @Advanced arguments
2011-08-19 15:06:37 -04:00
Mark DePristo 49e831a13b Should have checked in 2011-08-19 14:35:16 -04:00
Mauricio Carneiro 7b5fa4486d GenotypeAndValidate - Added docs to the @Arguments 2011-08-19 13:35:11 -04:00
Mark DePristo 9f7d4beb89 Merge branch 'help' 2011-08-19 13:14:02 -04:00
Mark DePristo 4d1fd17a97 GATKDoclet cleanup and documentation
-- Fixed bug in the way ArgumentCollections were handled that lead to failure in handling the dbsnp argument collection.
2011-08-19 13:13:41 -04:00
Ryan Poplin 0f25167efd minor fix in VariantEval docs 2011-08-19 11:01:04 -04:00
Mark DePristo 198955f752 GATKDoc descriptions for all standard codecs, or TODO for their owners
-- Also added vcf.gz support in the VCF codec.  This wasn't committed in the last round, because it was missed by the parallel documentation effort.
2011-08-19 09:57:21 -04:00
Guillermo del Angel 269ed1206c Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-08-19 09:32:20 -04:00