Commit Graph

13700 Commits (b69b256003fd6a9b8e1d7b9365419d544ba626c0)

Author SHA1 Message Date
Geraldine Van der Auwera b69b256003 Update pom versions to mark the start of GATK 3.4 development 2014-10-23 22:31:44 -04:00
Geraldine Van der Auwera eee94ec81f Update pom versions for the 3.3 release 2014-10-23 22:25:17 -04:00
Geraldine Van der Auwera a5aa4d5822 Merge remote-tracking branch 'unstable/master' 2014-10-23 22:23:22 -04:00
Geraldine Van der Auwera 22230cc820 Merge pull request #761 from broadinstitute/ks_junction_plugin_local_repo
Adding sysinternals:junction:1.04:exe to local repo.
2014-10-23 19:12:41 -04:00
Khalid Shakir 75c17bbd6f Adding sysinternals:junction:1.04:exe to local repo.
With Geraldine's blessing, works around issue where the repo for this exe keeps going down.
2014-10-24 05:33:47 +08:00
droazen 37464c38f2 Merge pull request #760 from broadinstitute/ks_queue_patches
Queue patches
2014-10-23 14:52:26 -04:00
Khalid Shakir ac33eda231 Queue patches.
Fixed Queue bug with bad localhost addresses.
Spaces in job names, while fine in GridEngine 6, break in (Son of) GE8.
2014-10-23 22:59:19 +08:00
Geraldine Van der Auwera 7dc8638ca4 Merge pull request #759 from broadinstitute/gg_minor_docfixes
Minor documentation clarifications in HC and a typo fix in SelectVariants
2014-10-22 22:20:26 -04:00
Geraldine Van der Auwera 3ba94b987c Minor documentation clarifications 2014-10-22 17:54:11 -04:00
rpoplin 0f89d1a362 Merge pull request #755 from broadinstitute/sc_Annotation_Docs_73647570
Improvements to documentation of variant annotations
2014-10-22 13:41:00 -04:00
rpoplin f093950bf9 Merge pull request #740 from broadinstitute/rp_ROC_curve_total_sensitivity
Adding total sensitivity option to ROCCurveNA12878 to help with Mauricio...
2014-10-22 11:33:16 -04:00
rpoplin e2fec7582e Merge pull request #756 from broadinstitute/gg_fixGenotypeAndValidate
Fix GenotypeAndValidate
2014-10-22 09:43:42 -04:00
kshakir be4cbf7035 Merge pull request #757 from broadinstitute/ks_smowton_scatter_contigs_fix
Improved scatter contigs algorithm to be fairer when splitting many contigs into few parts.
2014-10-22 19:27:02 +08:00
Khalid Shakir 26ba4c11aa Minor fixups for previous commit once tests (only runnable at Broad) were run.
Fixed off by one error in size calculation IntervalUtils.scatterContigIntervals().
In test for fewer files than intervals, adjusted expected intervals.
In test for more files than intervals, adjusted expected exception.
2014-10-22 17:37:37 +08:00
Chris Smowton a62dc84795 Improved scatter contigs algorithm to be fairer when splitting a large number of contigs into a small number of parts.
See also: http://gatkforums.broadinstitute.org/discussion/comment/16010

Signed-off-by: Khalid Shakir <kshakir@broadinstitute.org>
2014-10-22 16:26:17 +08:00
Sheila Chandran b3c5ed4414 Improvements to documentation of variant annotations
- Added or modified explanations for majority of variant annotations
	- Generalized NBaseCount to include all tech platforms (not just SOLiD)
2014-10-21 18:20:04 -04:00
Geraldine Van der Auwera 895b8c5931 Minor fix for missing INFO key definition in VCF header 2014-10-21 16:50:37 -04:00
droazen edaa78dea1 Merge pull request #743 from broadinstitute/gg_gsaweb_switchover
Switch GATKDocs publishing to new gsaweb VM
2014-10-21 12:27:51 -04:00
rpoplin c4fcd70a88 Merge pull request #754 from broadinstitute/rhl_variant_array_exception
Do not process a variant if it is too large (> readLength), and log an e...
2014-10-21 12:01:52 -04:00
rpoplin bcf6be0b08 Merge pull request #753 from broadinstitute/ldg_HCzeroDepth
Fix GenotypeGVCF bugs in -allSites mode
2014-10-21 12:00:04 -04:00
rpoplin 7ec38bf2a2 Merge pull request #752 from broadinstitute/pd_cran_license
Changed license of gsalib R package from BSD to MIT
2014-10-21 11:51:24 -04:00
rpoplin 312a833db3 Merge pull request #751 from broadinstitute/pd_bamout_ref_regions
Added -disableOptimizations argument to HaplotypeCaller.
2014-10-21 11:50:46 -04:00
Laura Gauthier 2b848ad859 Variants that become hom-ref after regenotyping in GenotypeGVCFs are now getting output in -allSites mode. 2014-10-21 08:21:53 -04:00
Laura Gauthier 5465e4484e For GenotypeGVCFs -allSites mode, make genotypes no-call if depth is zero. 2014-10-21 08:21:43 -04:00
Ron Levine 239151ac7b Do not process a variant if it is too large (> readLength), and log an error
remove final keyword before refMap and altMap, constructHaplotype() changes their values

return ArtificialHaplotype from constructHaplotype instaed of passing as an argument

Add logic so arraycopy does not throw an IndexOutOfBoundsException, add test for a long insert
2014-10-20 15:51:32 -04:00
Phillip Dexheimer f766608b4e Changed license of gsalib R package from BSD to MIT
- PT 75827540
2014-10-16 21:37:07 -04:00
Phillip Dexheimer b348ce8f25 Added -disableOptimizations argument to HaplotypeCaller.
* This argument is intended to be used in conjunction with -bamout, and disable early-exit optimizations to allow reference regions to be contained in the output bam
  * Also forcibly includes the reference haplotype in the set of haplotypes given to the BAMWriter
  * Made -dontTrimActiveRegions visible, as it is likely also desirable in this use case
  * Addresses PT 77731660
2014-10-16 21:11:20 -04:00
ldgauthier 5fa5724e4a Merge pull request #750 from broadinstitute/ldg_uniqueSamplesInCombineVariants
Throw UserException if input VCFs have duplicate samples but no genotype...
2014-10-16 07:57:27 -04:00
Laura Gauthier 0f08065ebc Throw UserException if input VCFs have duplicate samples but no genotypemergeoption is specified 2014-10-15 16:03:10 -04:00
rpoplin 286f4cc8a8 Merge pull request #749 from broadinstitute/ldg_CGPfasterTests
Decrease interval on CGP integration test to reduce test execution time
2014-10-15 15:53:48 -04:00
Ryan Poplin 2b67e46e29 Adding total sensitivity option to ROCCurveNA12878 to help with Mauricio's analyses.
-- We now keep a tally of uncalled sites so that they can be factored into the denominator of the sensitivity/specificity metric
2014-10-15 12:48:42 -04:00
Laura Gauthier 81482138ca Decrease interval on CGP integration test to reduce test execution time 2014-10-15 11:28:27 -04:00
rpoplin 0ad9daeac1 Merge pull request #747 from broadinstitute/gg_fixLicenseOmission
Updated license files and text
2014-10-15 11:26:42 -04:00
Geraldine Van der Auwera e7e8052f84 Updated license information
- Updated license files (private/protected) for version, address and a couple of legal clauses
- Updated license snippet throught the codebase
2014-10-14 17:10:12 -04:00
rpoplin 32bf46d8bf Merge pull request #748 from broadinstitute/rp_roc_curve_qual_field
In ROCCurveNA12878, if VQSLOD value is not present default to using the ...
2014-10-14 14:30:52 -04:00
Ryan Poplin 9680511cc3 In ROCCurveNA12878, if VQSLOD value is not present default to using the QUAL field instead to rank the variants. 2014-10-14 12:15:23 -04:00
rpoplin 426907ddd0 Merge pull request #744 from broadinstitute/gg_gatkdocs_annots_and_GSON
Output JSON version of docs for Galaxy
2014-10-14 11:41:16 -04:00
ldgauthier d259f3c84f Merge pull request #745 from broadinstitute/ldg_VariantAnnotatorDocs
Added docs to VariantFiltration is accordance with new htsjdk changes.  ...
2014-10-10 14:11:24 -04:00
jmthibault79 22a3c6e556 Merge pull request #742 from broadinstitute/rhl_prob_thresh_param_arg
Rhl prob thresh param arg
2014-10-10 12:55:01 -04:00
Laura Gauthier 0ecb85d321 Added docs to VariantFiltration is accordance with new htsjdk changes. Fixed typo in VariantAnnotator docs. 2014-10-10 11:54:24 -04:00
Ron Levine 36c27155af Made the threshold for the probability of a state being active a command line argument
remove TODO comment after activeProbThreshold

recover static ACTIVE_PROB_THRESHOLD for unit tests

Add min/max values for active_probability_threshold parameter

Move activeProbThreshold parameter to GATKArguemtnCollection

define ACTIVE_PROB_THRESHOLD in unit tests

add construction of argCollection in in ctor

Move arguments from GATKArgumentCollection to ActiveRegionWalker

Throw exception if threshold < 0 or > 1 in ActivityProfile ctor

max propogation distance parameter to ActiveRegionWalker for AcrtivityProfile

Use polymorphic getMaxProbPropagationDistance() so BandPassActivityProfile computes the crrect region size cutoff

Get the maxProbPropagationDistance from the super class's method, instead of directly, this is safer

Removed extraneous command line imports and make maxProbPropagationDistance a hidden argument

remove limit check for activeProbThreshold, not necessary because the check is made when imput as a command line arg

Remove extra 'region' in the doxygen param description for maxProbPropagationDistance
2014-10-10 10:36:02 -04:00
jmthibault79 4e099c1f44 Merge pull request #741 from broadinstitute/rhl_activiteregion_read_limits_args
Changed hardcoded downsampling max/min coverage values to parameters
2014-10-09 18:49:22 -04:00
Ron Levine 645d418015 Changed hardcoded downsampling max/min coverage values to parameters
Rename parameters using camel case and add to integration test

Correct documentation for maxReadsInRegionPerSample and minReadsPerAlignmentStart

Change the argument--minReadsPerAlignmentStart in the integration test from 50 to 5

'each genomic location' only pertains to minReadsPerAlignmentStart, not maxReadsInRegionPerSample
2014-10-09 17:09:26 -04:00
Geraldine Van der Auwera 3f21f63161 Output JSON version of docs for Galaxy 2014-10-09 06:42:25 -04:00
Geraldine Van der Auwera 58ca51e255 Switch GATKDocs publishing to new gsaweb VM 2014-10-08 21:07:58 -04:00
rpoplin 1cbf37c539 Merge pull request #739 from broadinstitute/rp_KB_reviews
Adding manual review.
2014-10-01 09:53:08 -04:00
rpoplin b0481ced87 Merge pull request #738 from broadinstitute/vrr_slow_integration_test_due_to_general_ploidy_exact_af_calculator
Reduce execution time of various integration tests
2014-10-01 09:52:04 -04:00
Valentin Ruano-Rubio a3ad6f63bd Reduce execution time of various integration tests
Story:

    https://www.pivotaltracker.com/story/show/79461912
2014-09-30 13:28:55 -04:00
Ryan Poplin d609b2cdbb Adding manual review. 2014-09-30 12:53:55 -04:00
rpoplin 329bd081b7 Merge pull request #736 from broadinstitute/rhl_remove_line
removed an unneed import that broke maven
2014-09-29 15:03:55 -04:00