Commit Graph

161 Commits (b5165b8d30b166c8dd2abfb85e2aee183e3f73e0)

Author SHA1 Message Date
meganshand b5165b8d30 Fix for out of date VCF version output 2015-11-03 17:35:47 -05:00
ldgauthier 3d1dc303b3 Merge pull request #1197 from broadinstitute/ts_ve_nullPointer
Prevent null pointer exception in PrintMissingComp module
2015-11-02 14:42:50 -05:00
Takuto Sato 33462c7b50 Removed the line that caused a null pointer, as the information it logged was not useful. Updated docs and added an integration test to ensure the code no longer throws the exception. 2015-11-02 12:45:09 -05:00
Laura Gauthier f7eb5d3082 Enable family-level stratification (if a ped file is provided) 2015-10-28 09:55:04 -04:00
Laura Gauthier fcaf37279c Finished draft of code for new map-combine-reduce annotation framework
All VQSR annotations can be generated in allele-specific mode
Pull out allele-specific annotations in AS_Standard annotation group
2015-10-27 09:23:29 -04:00
Ron Levine 36ca9fe898 Allow LeftAlignAndTrimVariants to handle alleles longer than the default processing window 2015-10-25 20:33:56 -04:00
Ron Levine 795fe75886 Update doc for multiallelics, trimming is the default behavior 2015-10-22 04:04:09 -04:00
Takuto Sato df7a482335 VariantAnnotator now supports annotating FILTER field from an external resource.
Updated the docs.
2015-10-14 14:26:21 -04:00
Ron Levine 2bcded11cb VariantAnnotator checks alleles when annotationg with external resource 2015-10-08 17:01:30 -04:00
Kate Noblett 506958a0b7 Implemented a new VariantEval evaulation module, MetricsCollection. Fixed null pointer exception, updated tests. 2015-09-30 17:21:30 -04:00
Geraldine Van der Auwera 118c559278 Trivial doc typo fix 2015-09-25 18:15:29 -04:00
Ami Levy Moonshine 1ad00cc9d4 fix typo in the ASEReadCounter document 2015-09-21 15:30:06 -04:00
Ron Levine 3ecabf7e45 Allow overriding ValidateVariants' hard-coded cutoff for allele length 2015-09-17 10:49:14 -04:00
Ron Levine 83a7012d69 Mask snps with --snpmask 2015-09-09 16:20:48 -04:00
Ron Levine 29ac64f6ce Calculate GenotypeAnnotations before InfoFieldAnnotations 2015-09-03 09:22:46 -04:00
Ron Levine 2afe3f7a21 Make GenotypeGVCFs subset Strand Allele Counts intelligently 2015-08-22 08:33:09 -04:00
Ron Levine 900fe3f675 Merge pull request #1132 from broadinstitute/rhl_rev_htsjdk
Move htsjdk & picard to rev 1.138
2015-08-20 11:58:41 -04:00
Bertrand Haas eae4c875a9 Logistic transform of MQ + jitter to capped MQ in VariantDataManager 2015-08-20 11:10:45 -04:00
Ron Levine beec624a63 Move htsjdk & picard to rev 1.138 2015-08-20 10:42:25 -04:00
Khalid Shakir 9bee183f6c Switched to using CRAM's SamReader.Indexing implementation.
CRAM now requires .bai index, just like BAM.
Test updates:
- Updated existing MD5s, as TLEN has changed.
- Tests multiple contigs.
- Tests several intervals per contig.
- Tests when `.cram.bai` is missing, even when `.cram.crai` is present.
Updated gatk docs for CRAM support, including:
- Arguments that work for both BAM and CRAM listed as such.
- Arguments that don't work for CRAM either explicitly say "BAM" or "doesn't work for CRAM".
- Instructions on how to recreate a `.cram.bai` using cramtools.
Cleaned up IntelliJ IDEA warnings regarding `Arrays.asList()` -> `Collections.singletonList()`.
2015-08-11 17:52:49 -03:00
Geraldine Van der Auwera 19bbe45cbc Updated licenses for 2015 2015-08-06 15:23:11 -04:00
David Benjamin ddb01058d3 moved DiffObjects 2015-08-05 21:19:02 -04:00
Geraldine Van der Auwera 875c7ffa1a Fixed typos and made some argument docs improvements 2015-07-29 23:06:19 -04:00
Louis Bergelson 9d9827f176 Merge pull request #1031 from broadinstitute/lb_update_for_java8
Updated gatk so it compiles with java 8
2015-07-28 11:09:19 -04:00
Joseph White 3bd988825f Removed walkers for handling Beagle data
Added deprecation statements to DeprecatedToolChecks.java
    Removed integration test for Beagle walker
    Added URL for Beagle documentation
2015-07-21 18:36:08 -04:00
Eric Banks 178bf12b27 Merge pull request #1046 from broadinstitute/rhl_catvariants_sort
Fix for mis-sorted VCF files in CatVariants
2015-07-21 17:37:27 -04:00
Ron Levine 6e46b3696e Merge contiguous intervals properly 2015-07-14 15:23:37 -04:00
John Wallace 8fc631b7ae Fix for mis-sorted VCF files in CatVariants
When using CatVariants, VCF files were being sorted solely on the base
pair position of the first record, ignoring the chromosome.  This can
become problematic when merging files from different chromosomes,
espeically if you have multiple VCFs per chromosome.

As an example, assume the following 3 lines are all in separate files:
1       10
1       100
2       20

The merged VCF from CatVariants (without -assumeSorted) would read:
1       10
2       20
1       100

This has the potential to break tools that expect chromosomes to be
contiguous within a VCF file.

This commit changes the comparator from one of Pair<Integer, File> to
one of Pair<VariantContext, File>.  We construct a
VariantContextComparator from the provided reference, which will sort
the first record by chromosome and position properly.  Additionally, if
-assumeSorted is given, we simply use a null VariantContext as the first
record, which will all be equal (as all will be null)
2015-07-14 14:12:31 -04:00
Louis Bergelson e1c41b2c38 Updated gatk so it compiles on java 8
updated cofoja to 1.2 from 1.0
added explicit type casts in places that java 8 required them
2015-06-26 15:59:46 -04:00
Ron Levine b35085ca28 Indexing parameters not required if output file has the g.vcf.gz extensionv 2015-06-13 11:46:56 -04:00
Geraldine Van der Auwera 95f2899f05 User (mnw21cam) patch to fix DoC slowdown in 3.4 2015-06-05 21:12:46 -04:00
Ron Levine a6ca97ef14 Site-level selection based on genotype filter status 2015-05-21 11:27:20 -04:00
Geraldine Van der Auwera d1a7edd796 Update pom versions to mark the start of GATK 3.5 development 2015-05-15 00:44:54 -04:00
Geraldine Van der Auwera f19618653a Update pom versions for the 3.4 release 2015-05-15 00:40:39 -04:00
Geraldine Van der Auwera 8b20523f5e Merge pull request #979 from broadinstitute/ami-fixASE-bug
solve bug - now work also when the reads does not have mate
2015-05-14 21:09:52 -04:00
David Roazen caafe84e74 Rev htsjdk to version 1.132 and picard to version 1.131, and switch to using the versions in maven central
-We now pull htsjdk and picard from maven central.

-Updated the GATK codebase as necessary to adapt to changes in the Feature
 interface.

-Since VCFHeader now requires that all header lines have unique keys, uniquified
 the keys of GVCFBlock header lines by including the min/max GQ in the key.
 Updated MD5s accordingly.

-Other MD5s changed as a result of an htsjdk fix to eliminate "-0" in VCF output.
2015-05-14 15:26:23 -04:00
Ami Levy-Moonshine 536d550794 solve bug - now work also when the reads does not have mate
reads with no mate will be counted as valid reads
2015-05-12 17:51:01 -04:00
Ron Levine 4a75d54e65 Added invert and exclude flags for variant selection queries 2015-05-12 15:08:28 -04:00
Joseph White abb6bc6f57 Correct errant array element swap in FAM file output.
dad and mom are swapped; paternal first, then maternal

updated MD5 chksums for test files

remove commented lines
2015-05-11 20:45:50 -04:00
Geraldine Van der Auwera 5d8b9a7c20 Moved MQ0 out of HC exclusion and into StandardUGAnnotation 2015-05-03 01:04:49 +02:00
Geraldine Van der Auwera 071d82d1bf Un-exclude SD and TRA from HC annotators; resolves #966
Exclude MQ0BySample
Move SD and TRA to new StandardUGAnnotation interface
There is now annotation interface (StandardUGAnnotation) holding annots that are standard in UG but should't be used as they are now with HC. This allows us to not have to exclude these annotations explicitly in HC, but still be able to use them for development purposes.
2015-05-03 00:45:53 +02:00
Geraldine Van der Auwera e49f6dfd0f Merge pull request #970 from broadinstitute/gg_minor_docfixes
Fairly minor if plentiful fixes to various gatkdocs. Merging this without formal review since all tests pass, the gatkdocs build, and no one really wants to review corrections to grammar, typos and layout for 120+ documents. Review will be done by users in production ;-)
2015-05-03 00:36:12 +02:00
Geraldine Van der Auwera 919c3eaa2e Numerous doc fixes; mostly formatting and clarifications 2015-05-03 00:28:46 +02:00
Ron Levine 9ff827c83a More allele trimming for VariantAnnotator 2015-04-29 21:11:49 -04:00
Ron Levine d5f98e99f0 Bypass reads with a bad CIGAR length 2015-04-21 11:55:56 -04:00
Khalid Shakir 90b579c78e CatVariants now allows different input / output file types.
Escaping the CatVariantsIntegrationTest classpaths for possible spaces in the directory names.
2015-04-13 14:39:46 -03:00
Ron Levine fe87484074 Update -mv example documentation
Made general doc fixes
2015-04-01 02:37:42 -04:00
Geraldine Van der Auwera d7f7022dce Merge pull request #904 from broadinstitute/pd_orig_dp
Added keepOriginalDP argument to SelectVariants
2015-03-30 09:01:33 -04:00
ldgauthier 0101003138 Merge pull request #899 from broadinstitute/ldg_M2_tandemRepeatsAndContamination
Lots of changes to M2:
2015-03-30 07:58:35 -04:00
Geraldine Van der Auwera 87b3dddb39 Merge pull request #894 from broadinstitute/gg_ami_docs_license
Edited ASEReadCounter documentation
2015-03-28 13:15:24 -04:00