Commit Graph

6286 Commits (ad373ffa7e1d2e1ddf1e01ec2bfa8991f84674bc)

Author SHA1 Message Date
Mark DePristo ad373ffa7e Broke down and implemented parallel get. Now running 10x parallel no problems on gsa1. 2011-07-14 09:12:43 -04:00
Mark DePristo 1390f354dc Giving up on parallel s3 fetching. The solution here is to do incremental processing, and not try to download 1.5M records at once, but obtain the ~10K per day that are appearing. 2011-07-13 23:12:19 -04:00
Mark DePristo ae044af678 Forgot to comment out a debug 2011-07-13 22:39:58 -04:00
Mark DePristo caa3629467 Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-13 22:38:27 -04:00
Mark DePristo d6c1540e57 Parallel version. 2011-07-13 22:37:49 -04:00
Mark DePristo 63c58c5f7e Log file no longer optional. 2011-07-13 21:41:15 -04:00
Mark DePristo d163a2106a Now uses the log file to determine which files exist locally, avoiding the potentially expensive check on disk 2011-07-13 21:36:02 -04:00
Mauricio Carneiro a4ab19d040 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-13 15:14:06 -04:00
Eric Banks 0c54c796ed Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-13 14:57:33 -04:00
Eric Banks bb0e3a26fc Added integration test for VCF writing. Also, bug fix for writing the GT-free records. 2011-07-13 14:57:21 -04:00
Mauricio Carneiro df996a1a73 more progress report for the Data Processing Pipeline.
Bam lists can now have empty lines, comments and whitespaces anywhere.
2011-07-13 14:53:58 -04:00
Eric Banks 6a431da554 Don't output source and ref header lines anymore. Short-term motivation for this is that I'd like this tool when run on a VCF to emit the exact same VCF. Long-term motivation is that these tags should be output by the VCF writer itself for all tools. 2011-07-13 14:40:01 -04:00
Mauricio Carneiro e2f2917bd2 Merged bug fix from Stable into Unstable 2011-07-13 13:00:55 -04:00
Mauricio Carneiro ff4e31c554 Changing the file names as per Kris request. 2011-07-13 12:59:18 -04:00
Menachem Fromer 74aa49e423 Merged bug fix from Stable into Unstable 2011-07-13 12:12:42 -04:00
Menachem Fromer fa3ff53508 Filters should only be applied to the new VC if the old VC had filters applied 2011-07-13 11:58:16 -04:00
Mark DePristo e86113e537 Minor fixes for logging. Now logs even if you don't need to download the file (it's a complete log now).
Bug fix for del logging.
2011-07-13 10:27:24 -04:00
Mark DePristo b04b8b20a5 Added support for -p log so that we can track progress without trying to ls a directory with 1.5M entries in it. 2011-07-13 10:22:32 -04:00
Mark DePristo 6450b48951 manageGATKS3Logs now downloads and deletes files in groups of 100 files by default. This should significantly improve the performance of the S3 log synchronization. 2011-07-13 10:14:38 -04:00
Eric Banks 969227c657 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-13 10:01:28 -04:00
Eric Banks 797c50e689 Fixing integration tests I broke yesterday; removing batch merging test since we don't support that anymore. 2011-07-13 10:01:23 -04:00
Eric Banks 6007eea3ff Allowing VCF records without GTs in vf4.1 2011-07-13 09:56:08 -04:00
Christopher Hartl 95040d95b9 Adding in check for filtered site (Sorry Mark, looks like it wasn't checking the validated rod, only the mask). Also by allowing user to lowercase SNPs, could miss 'SNP_TOO_NEAR_PROBE', now we properly check for that. 2011-07-12 19:21:26 -04:00
Christopher Hartl 61dad4f090 Merge branch 'master' of ssh://chartl@tin.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 18:33:30 -04:00
Christopher Hartl 30768eccbb Big change to PSP2: Amplicon sequence no longer lower-cased for repetitiveness, but instead for non-uniqueness via alignment by bwa. Performance heavily dependent on length of sequence (duh), with size=30 a good balance, but default is 20 because that's the default length of a sequenom primer. Indentation changes to other stuff. 2011-07-12 18:33:12 -04:00
Mauricio Carneiro 60870b360a Fixed the calculation of the allele count prior, it was using ac instead of maxAlleleCount. 2011-07-12 17:18:52 -04:00
Mauricio Carneiro d21388f0cb Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:56:38 -04:00
Mauricio Carneiro 775d2c2598 Added VQSR to the ReducedBAM evaluation script. Our tests need to address the annotations used by VQSR so we can actually measure the impact of changing the parameters in the ReduceReads walker (especially context size). 2011-07-12 15:56:24 -04:00
Ryan Poplin c944019678 Adding dev qscript I used to perform the exome t2d+1kg calling experiment 2011-07-12 15:44:45 -04:00
Ryan Poplin 837fb8f689 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:39:26 -04:00
Ryan Poplin 5077c94d85 Adding MappingQualityUnavailableReadFilter to the SNP and indel CountCovariates 2011-07-12 15:39:07 -04:00
Mark DePristo 2092fb439c Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:29:52 -04:00
Roger Zurawicki 6ee8a86197 Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:26:13 -04:00
Roger Zurawicki 7991d69ba4 I added experimental function in the ReducedBAMEvaluation.
At the beginning of the scrpit you can specify a list of values to test and it will process the ReduceReadsWalker for your parameter.

I also added a method to convert the number when naming files to be sort-friendly.
2011-07-12 15:25:43 -04:00
Mark DePristo 01fd6a6949 Merge branch 'master' of ssh://gsa1/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-12 15:20:44 -04:00
Mark DePristo ccedd6ff4c Difference is now the general form -- used to be SummarizedDifference. The old Difference class is now a subclass of Difference that includes pointers to specific the master and test DiffElements.
Added a size() function that calculates the number of elements tree from a DiffElement.
2011-07-12 15:20:28 -04:00
Eric Banks a2597e7f00 This commit incorporates several different changes that each pretty much break all the VCF-based integration tests, so I bunched them all together. We now officially emit VCF4.1 files (woo hoo), which means that the VCF headers are now all different (header version is 4.1 plus counts for some of the annotations are 'A' or 'G'). Also, I've added a Read Filter for reads with MQ=255 ('unavailable' in the SAM spec) and have applied this to the UG and the RMS MQ annotation. 2011-07-12 14:11:53 -04:00
Ryan Poplin 329c3d8050 Merged bug fix from Stable into Unstable 2011-07-12 13:55:51 -04:00
Ryan Poplin 73735863b0 Fix for the case of requesting genotype for a sample that doesn't exist in a VariantContext 2011-07-12 13:55:21 -04:00
Guillermo del Angel c4c145afb9 Merged bug fix from Stable into Unstable 2011-07-12 13:44:48 -04:00
Guillermo del Angel cfe43e3971 Bug fix for Genotype given alleles: if we are in INDEL mode ignore SNPs and MNPs instead of emitting an empty site with alleles but no annotations 2011-07-12 13:43:46 -04:00
Mark DePristo 05212aea62 reader now takes an argument for the maximum number of elements to read from the file. 2011-07-12 08:53:19 -04:00
Mark DePristo 8056a3fe89 getElement() now uses O(1) get from hash instead of linear O(n) search. Enables us to read large files easily. 2011-07-12 08:52:31 -04:00
Mark DePristo f313e14e4e Now deletes the dump directory on ant clean
Moving diffengine tests from private to public
2011-07-12 08:50:58 -04:00
Eric Banks d7d15019dd Adding support for other simple header line types (e.g. ALT) and cleaning up the interface a bit. 2011-07-12 01:16:21 -04:00
Eric Banks 400b0d4422 Merge branch 'master' of ssh://nickel.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-11 23:38:57 -04:00
Mark DePristo d5056ad899 Merge branch 'master' into diffit 2011-07-11 23:16:15 -04:00
Mark DePristo 893cc2e103 Making the package public, so there's no dependances from public -> private 2011-07-11 23:15:08 -04:00
Mark DePristo 5e593793af DiffEngine utility function simpleDiffFiles
printSummaryReport now uses GATKReport for nice formating
Moved print formatting arguments into inner class provided to printing functions themselves, not the class
BAMDiffableReader only reads 1000 entries to avoid performance issue.  Work around for BAM files with non-unique names
Uncommented all of the incorrectly commented out CombineVariants integrationtests
BaseTest now uses DiffEngine to provide inline differences to VCF and BAM files
2011-07-11 23:10:27 -04:00
Khalid Shakir d11155ce2e Merge branch 'master' of ssh://gsa3.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2011-07-11 19:19:54 -04:00