Commit Graph

66 Commits (ab75b08ea7f9353e2b0fec0e52ff8dbbbee7db8c)

Author SHA1 Message Date
Ron Levine ab75b08ea7 Remove unused compressed_block_size and close BlockCompressedInputStream 2017-02-17 12:22:53 -05:00
Ron Levine 1d36d9fd69 Move htsjdk to ver 2.9.0 and picard to ver 2.8.3 2017-02-17 07:03:03 -05:00
Ron Levine 172db666d6 Output files with the vcf.gz extension are gzipped, containing .bcf not as an extension result in VCF" 2016-12-05 22:25:59 -05:00
Geraldine Van der Auwera 234ccdf0c3 Merge pull request #1496 from broadinstitute/db_m2_downsampling
Expose downsampling parameters as CLI arguments to Mutect2
2016-12-05 21:53:25 -05:00
David Benjamin b1f2301dd3 Add downsampling arguments to Mutect
- maxReadsInRegionPErSample, minReadsPerAlignment start are now M2 args
	- maxReadsInMemoryPerSample is an activeRegionWalker arg
2016-12-05 14:12:22 -05:00
Geraldine Van der Auwera b42dc1624b Documentation fixes
- Fix missing closing code block tag
	- SOR fix + minor fix to template
	- Minor typo fixes
	- Make no_cmdline_in_header arg visible in docs
	- Caveats for UG-only args that are difficult to move out of common collection
	- Reference -L and -XL in -gvcf documentation
	- Annotation doc fixes (dsde-docs#1289)
	- Unhide some ContEst args and make Advanced
	- Fix inputPrior error message
	- Update web urls
	- Add JEXL doc link
2016-12-05 14:09:44 -05:00
Ron Levine 68b6f8f638 Replace VariantContextWriterFactory with VariantContextWriterBuilder 2016-11-30 16:04:25 -05:00
Ron Levine cfd3ffa2c0 Replace SAMFileReader with calls to SamReaderFactory 2016-10-14 11:22:54 -04:00
Ron Levine f6c18a5182 Throw an exception if the BQSR input covariants file is not found 2016-08-11 12:46:14 -04:00
Andrii Nikitiuk a465c87ff8 Added support for directly reading SRA runs 2016-08-02 15:21:14 -04:00
Ron Levine aace73e884 Enable control of reporting periodicity 2016-07-13 07:24:03 -04:00
Ron Levine 3c5eac8c17 Move htsjdk and picard to version 2.5.0 2016-06-28 09:42:32 -04:00
sooheelee 6fe80d53d0 Improve documentation
Clarified that this also filters supplementary alignments.
2016-06-23 16:20:00 -04:00
Samuel Lee 76bb8fd9e5 Allows GatherBqsrReports to accept a .list file as input. 2016-06-22 12:39:18 -04:00
Geraldine Van der Auwera d87345cd1d GATKDocs overhaul
- Fixed displaying of default values
    - Removed code cruft
    - Reorganized tooldoc categories and improved names
    - Reorganized tools within categories where applicable
    - Touched up various tool docs
    - Switched default gatkdocs output to html
    - Added parameter in agrregator pom to control output type
    - Set gatkdocs publishing script to output php
    - Deprecated GenotypeAndValidate walker
    - Added back PhoneHome arguments with @Deprecated annotations
2016-05-29 16:35:08 -04:00
Geraldine Van der Auwera 0769c8ae3e Remove Phone Home 2016-05-27 16:16:29 -04:00
Geraldine Van der Auwera 5b80c92cb7 Improved article linking in error messages 2016-05-27 13:49:31 -04:00
Geraldine Van der Auwera 3b7e0c56bf Moved post-IR MQ reverter filter to public 2016-05-27 12:39:58 -04:00
Ron Levine 35a06879f1 Move htsjdk and picard to version 2.3.0 2016-05-16 14:50:00 -04:00
Geraldine Van der Auwera 14fe8b1e0e Moved BQSRGatherer and dependencies to the public module 2016-04-27 07:15:28 -04:00
Ron Levine f337b45724 Move htsjdk and picard to version 2.0.0
Conflicts:
	protected/gatk-tools-protected/src/test/java/org/broadinstitute/gatk/tools/walkers/genotyper/UnifiedGenotyperGeneralPloidySuite1IntegrationTest.java
	protected/gatk-tools-protected/src/test/java/org/broadinstitute/gatk/tools/walkers/genotyper/UnifiedGenotyperGeneralPloidySuite2IntegrationTest.java
	protected/gatk-tools-protected/src/test/java/org/broadinstitute/gatk/tools/walkers/genotyper/UnifiedGenotyperIndelCallingIntegrationTest.java
	protected/gatk-tools-protected/src/test/java/org/broadinstitute/gatk/tools/walkers/haplotypecaller/HaplotypeCallerIntegrationTest.java
2016-04-25 14:51:25 -04:00
Yossi Farjoun b471884d97 Added run-time information to log output
Also updated copyright date
2016-03-11 16:43:03 -05:00
Geraldine Van der Auwera 9a306ca221 Update licenses 2016-03-05 01:09:43 -08:00
Geraldine Van der Auwera 2b70f14740 Misc documentation improvements
Added caveat to VariantFiltration documentation
  Fixed PON creation example in M2 doc
  Improved MalformedReadFilter doc
  Updated N CIGAR error message
2016-03-03 15:48:54 -08:00
Ron Levine ed933013fe Remove variant contig order check 2016-01-16 19:32:28 -05:00
meganshand 2570cab24c Assorted documentation fixes, enhancements and reorganization.
See issues referenced by the pull request for details.
2015-11-20 22:44:46 -05:00
Ron Levine 0b3b09e3ff Move htsjdk & picard to version 1.141 2015-11-20 16:26:26 -05:00
Ron Levine ccaddefa19 Validate VCF with sequence dictionary 2015-11-20 09:23:24 -05:00
Mark Fleharty 19af5724c5 Fixed an NA12878 Knowledgebase test, and made the RDQ option for BQSR binning hidden 2015-10-27 09:44:26 -04:00
Chris Norman e776502c49 Fix Sample mergeValues failure when merging identical string values (#1156). 2015-10-12 09:56:05 -04:00
Ron Levine 3ecabf7e45 Allow overriding ValidateVariants' hard-coded cutoff for allele length 2015-09-17 10:49:14 -04:00
Khalid Shakir 24e24b9468 Using `SamIndexes.asBaiSeekableStreamOrNull()` to support `.cram.crai`.
Updated other IntelliJ IDEA warnings in GATKBAMIndex.
Updated example .cram files to match versions generated by current GATK/HTSJDK.
Bumped HTSJDK and Picard to 1.139 releases.
Added support for using `-SNAPSHOT` of HTSJDK in the future.
2015-09-14 12:20:36 -04:00
Mark Fleharty daeb55429e Adding Static Binning to BQSR 2015-08-24 13:36:17 -04:00
Ron Levine beec624a63 Move htsjdk & picard to rev 1.138 2015-08-20 10:42:25 -04:00
Yossi Farjoun 69fd4af15a Merge pull request #1111 from jsilter/overclippedreadfilter_endsoption
Add additional option to OverclippedReadFilter
2015-08-12 10:43:52 -04:00
Jacob Silterra 62625b4bc6 Add option to not require soft-clips on both ends
Previous version of OverclippedReadFilter would only filter a read if both ends of a read had a soft-clipped block.
This adds a boolean option to relax that requirement, and only require 1 soft-clipped block, while also filtering on read length - softclipped length
2015-08-12 10:38:27 -04:00
Khalid Shakir 9bee183f6c Switched to using CRAM's SamReader.Indexing implementation.
CRAM now requires .bai index, just like BAM.
Test updates:
- Updated existing MD5s, as TLEN has changed.
- Tests multiple contigs.
- Tests several intervals per contig.
- Tests when `.cram.bai` is missing, even when `.cram.crai` is present.
Updated gatk docs for CRAM support, including:
- Arguments that work for both BAM and CRAM listed as such.
- Arguments that don't work for CRAM either explicitly say "BAM" or "doesn't work for CRAM".
- Instructions on how to recreate a `.cram.bai` using cramtools.
Cleaned up IntelliJ IDEA warnings regarding `Arrays.asList()` -> `Collections.singletonList()`.
2015-08-11 17:52:49 -03:00
Geraldine Van der Auwera 19bbe45cbc Updated licenses for 2015 2015-08-06 15:23:11 -04:00
Geraldine Van der Auwera 719bb15340 Merge pull request #1019 from broadinstitute/rhl_var_index_param_gz
Indexing parameters not required if output file has the g.vcf.gz exte…
2015-06-17 14:30:20 -04:00
Ron Levine b35085ca28 Indexing parameters not required if output file has the g.vcf.gz extensionv 2015-06-13 11:46:56 -04:00
Ron Levine dbed660183 Add spannning deletions allele 2015-06-12 16:43:06 -04:00
Eric Banks 8c81e7df95 Added a new filter that can be used to remove reads that are too small and overly clipped. 2015-05-22 14:33:35 -04:00
David Roazen caafe84e74 Rev htsjdk to version 1.132 and picard to version 1.131, and switch to using the versions in maven central
-We now pull htsjdk and picard from maven central.

-Updated the GATK codebase as necessary to adapt to changes in the Feature
 interface.

-Since VCFHeader now requires that all header lines have unique keys, uniquified
 the keys of GVCFBlock header lines by including the min/max GQ in the key.
 Updated MD5s accordingly.

-Other MD5s changed as a result of an htsjdk fix to eliminate "-0" in VCF output.
2015-05-14 15:26:23 -04:00
Geraldine Van der Auwera 919c3eaa2e Numerous doc fixes; mostly formatting and clarifications 2015-05-03 00:28:46 +02:00
Ron Levine d5f98e99f0 Bypass reads with a bad CIGAR length 2015-04-21 11:55:56 -04:00
Alex Baumann 024ec69e97 Modify GATK command line header for unique keys
The GATK command line header keys were being repeated in the VCF and
subsequently lost to a single key value by HTSJDK.  This resolves
the issue by appending the name of the walker after the text
"GATKCommandLine" and a number after that if the same walker was
used more than once in the form: GATKCommandLine.(walker name) for
the first occurrence of the walker, and GATKCommandLine.(walker name).#
where # is the number of the occurrence of the walker (e.g.
GATKCommandLine.SomeWalker.2 for the second occurrence of SomeWalker).
Integration test added to EngineFeaturesIntegrationTest to verify
two runs of same walker follow expected form.

Resolves #909
See also: HTSJDK #43
2015-04-02 13:56:11 -04:00
Ron Levine aef0a83c52 Automatically choose indexing strategy by file extension 2015-03-27 11:10:35 -04:00
Phillip Dexheimer 3b567d7a98 Fixed logging of 'out' command line parameter in VCF headers 2015-03-18 23:12:13 -04:00
Phillip Dexheimer 6ffa295963 Regression: The new 'includeUnmapped' PartitionBy annotation was incorrectly set for HC
Fixes #828
2015-03-13 00:24:57 -04:00
Ron Levine 71d68c3d93 Fix NotPrimaryAlignmentFilter documentation 2015-03-05 20:30:46 -05:00