Commit Graph

16 Commits (96e29d3d94ceaa9e7d8a478f6a5d146c19556cee)

Author SHA1 Message Date
Eric Banks abb67cfa5e Fixed bug in generating AD values when new alleles are present for genotpying GVCFs.
This was a dumb mistake that wasn't well tested (but is now).
2014-02-09 15:15:19 -05:00
Eric Banks d689f61005 Fixed up some of the genotype-level annotations being propogated in the single sample HC pipeline.
1. AD values now propogate up (they weren't before).
2. MIN_DP gets transferred over to DP and removed.
3. SB gets removed after FS is calculated.

Also, added a bunch of new integration tests for GenotypeGVCFs.
2014-02-07 12:47:54 -05:00
Eric Banks db68d3fa10 Fixing failing unit tests 2014-02-07 12:24:14 -05:00
Eric Banks 2648219c42 Implementation of a hierarchical merger for gVCFs, called CombineGVCFs.
This tool will take any number of gVCFs and create a merged gVCF (as opposed to
GenotypeGVCFs which produces a standard VCF).

Added unit/integration tests and fixed up GATK docs.
2014-02-07 08:49:18 -05:00
Valentin Ruano Rubio 988e3b4890 Merge pull request #487 from broadinstitute/vrr_reference_model_with_trimming
Get gVCF to work without --dontTrimActiveRegions
2014-02-05 22:52:17 -05:00
Valentin Ruano-Rubio 98ffcf6833 Get gVCF to work without --dontTrimActiveRegions
Story:

https://www.pivotaltracker.com/story/show/65048706
https://www.pivotaltracker.com/story/show/65116908

Changes:

ActiveRegionTrimmer in now an argument collection and it returns not only the trimmed down active region but also the non-variant containing flanking regions
HaplotypeCaller code has been simplified significantly pushing some functionality two other classes like ActiveRegion and AssemblyResultSet.

Fixed a problem with the way the trimming was done causing some gVCF non-variant records no have conservative 0,0,0 PLs
2014-02-05 22:50:45 -05:00
Ryan Poplin 693bfac341 Bug fix for missing annotations in CombineReferenceCalculationVariants. They were being dropped in the handoff between engines in a couple of places.
-- Updated single sample pipeline test data using Valentin's files and re-enabled CRCV tests
2014-02-05 12:58:48 -05:00
Eric Banks 740b33acbb We were never validating the sequence dictionary of tabix indexed VCFs for some reason. Fixed.
These changes happened in Tribble, but Joel clobbered them with his commit.
We can now change the logging priority on failures to validate the sequence dictionary to WARN.
Thanks to Tim F for indirectly pointing this out.
2014-02-05 10:12:38 -05:00
Eric Banks 9cac24d1e6 Moving logging status of VCF indexing to DEBUG instead of INFO, otherwise it's painful when reading in lots of files 2014-02-05 10:12:37 -05:00
Eric Banks 91bdf069d3 Some updates to CRCV.
1. Throw a user error when the input data for a given genotype does not contain PLs.
2. Add VCF header line for --dbsnp input
3. Need to check that the UG result is not null
4. Don't error out at positions with no gVCFs (which is possible when using a dbSNP rod)
2014-02-05 10:12:37 -05:00
David Roazen 76086f30b7 Temporarily disable tests that started failing post-maven
Joel is working on these failures in a separate branch. Since
maven (currently! we're working on this..) won't run the whole
test suite to completion if there's a failure early on, we need
to temporarily disable these tests in order to allow group members
to run tests on their branches again.
2014-02-04 15:31:24 -05:00
David Roazen 3b2f07990d Re-break the MWUnitTest for Joel to debug 2014-02-04 15:19:09 -05:00
David Roazen c9032f0b5c Fix failing unit tests 2014-02-04 03:05:30 -05:00
Khalid Shakir d1a689af33 Added new utility files used by maven build, including the ant-bridge script. 2014-02-03 13:50:46 -05:00
Khalid Shakir 1e25a758f5 Moved files to maven directories.
Here are the git moved directories in case other files need to be moved during a merge:
  git-mv private/java/src/        private/gatk-private/src/main/java/
  git-mv private/R/scripts/       private/gatk-private/src/main/resources/
  git-mv private/java/test/       private/gatk-private/src/test/java/
  git-mv private/testdata/        private/gatk-private/src/test/resources/
  git-mv private/scala/qscript/   private/queue-private/src/main/qscripts/
  git-mv private/scala/src/       private/queue-private/src/main/scala/
  git-mv protected/java/src/      protected/gatk-protected/src/main/java/
  git-mv protected/java/test/     protected/gatk-protected/src/test/java/
  git-mv public/java/src/         public/gatk-framework/src/main/java/
  git-mv public/java/test/        public/gatk-framework/src/test/java/
  git-mv public/testdata/         public/gatk-framework/src/test/resources/
  git-mv public/scala/qscript/    public/queue-framework/src/main/qscripts/
  git-mv public/scala/src/        public/queue-framework/src/main/scala/
  git-mv public/scala/test/       public/queue-framework/src/test/scala/
2014-02-03 13:50:44 -05:00
Khalid Shakir faaef236ea Moved gsalib, R and other resources, Queue GATK extensions generator, Queue version java files. 2014-02-03 13:49:21 -05:00