Commit Graph

2 Commits (75a0d0b193b78c645765135fd31c90ec5411952e)

Author SHA1 Message Date
David Roazen 46edab6d6a Use the new downsampling implementation by default
-Switch back to the old implementation, if needed, with --use_legacy_downsampler

-LocusIteratorByStateExperimental becomes the new LocusIteratorByState, and
the original LocusIteratorByState becomes LegacyLocusIteratorByState

-Similarly, the ExperimentalReadShardBalancer becomes the new ReadShardBalancer,
with the old one renamed to LegacyReadShardBalancer

-Performance improvements: locus traversals used to be 20% slower in the new
downsampling implementation, now they are roughly the same speed.

-Tests show a very high level of concordance with UG calls from the previous
implementation, with some new calls and edge cases that still require more examination.

-With the new implementation, can now use -dcov with ReadWalkers to set a limit
on the max # of reads per alignment start position per sample. Appropriate value
for ReadWalker dcov may be in the single digits for some tools, but this too
requires more investigation.
2012-12-10 09:44:50 -05:00
David Roazen cb84a6473f Downsampling: experimental engine integration
-Off by default; engine fork isolates new code paths from old code paths,
so no integration tests change yet

-Experimental implementation is currently BROKEN due to a serious issue
involving file spans. No one can/should use the experimental features
until I've patched this issue.

-There are temporarily two independent versions of LocusIteratorByState.
Anyone changing one version should port the change to the other (if possible),
and anyone adding unit tests for one version should add the same unit tests
for the other (again, if possible). This situation will hopefully be extremely
temporary, and last only until the experimental implementation is proven.
2012-09-06 15:03:27 -04:00