Commit Graph

319 Commits (35543b9cbab7ff489b2eb8fb3bdbf518f9e3cf0d)

Author SHA1 Message Date
Eric Banks 0a98a6aa8d Adding extraDocs tag per Mauricio's request 2012-07-25 18:23:18 -04:00
Eric Banks 05fa377a8e Adding GATK categories to standard walkers. Will add to remaining walkers after the next successful release (so that I can see which walkers are public and still need it). 2012-07-25 16:05:47 -04:00
Ryan Poplin 2e486d83e2 Updating HaplotypeCaller docs and expanding integration tests. 2012-07-23 10:05:42 -04:00
Mauricio Carneiro 116885a450 Removed the "Walker" suffix from all walkers that had it.
* Did not touch archived walkers... those can be named whatever.
   * Kept abstract classes that end in Walker untouched (e.g. LocusWalker, ReadWalker, ...)
   * Renamed a few inner classes due to conflict when stripping off Walker from their outer classes: ContigStats, FlagStats and FastaStats.
2012-07-20 17:27:11 -04:00
Ryan Poplin 1592841c93 New function for merging nearby events into MNPs or complex substitutions. Added extensive unit tests. 2012-07-19 13:16:33 -04:00
Guillermo del Angel c16f9f2f15 a) Use new method to check for GATK Like, b) minor improvements to indel pool caller (more to come): brain-dead, quick way to limit number of alt alleles to genotype. We can't process too many alt alleles because of the combinatorial explosion of GL values with high ploidy, and some STR validation targets had up to 12 alt alleles, resulting of GL vectors of > 1e8 elements. Can't use pileup elements since typically not many alleles will be in one pileup, and different alleles will appear in different samples, TBD a nicer solution. c) Commit to posterity scala script for large scale validation calling, still work in progress 2012-07-19 10:24:08 -04:00
Guillermo del Angel 40b8c7172c Pool Caller refactoring in preparation of GATK 2.0: a) PoolCallerUnifiedArgumentCollection disappeared, and arguments moved to UnifiedArgumentCollection. b) PoolCallerWalker is no longer needed and redundant, all functionality subsumed by UG. UG now checks if GATK is lite - if so, don't allow ploidy > 2. c) Moved pool classes from private to protected. d) Changed the way to specify ploidy. Instead of specifying samples per pool and having ploidy = 2*samplesPerPool, have user specify ploidy directly, which is cleaner. Update tests accordingly. We can now call triploid seedless grape genotypes correctly in theory. e) Renamed argument -reference to -reference_sample_calls since the former is ambiguous and it's not clear what it refers to. 2012-07-17 15:27:04 -04:00
Eric Banks b0d99fd10d Merge branch 'master' of ssh://gsa2.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2012-07-17 15:12:28 -04:00
Eric Banks 305db8c0d1 Total rewrite of the isGATKLite() functionality with help of Khalid/David. PluginManager was not working for us. 2012-07-17 15:11:03 -04:00
Ryan Poplin c55934043e Moving HaplotypeCaller from private to protected 2012-07-17 14:41:19 -04:00
Eric Banks 3a64398d07 Cleaned up the isGATKLite check 2012-07-17 12:46:16 -04:00
Eric Banks 62c5228048 1) Revert previous change - indel recalibration is turned on by default and users of the Lite version will need to turn it off to avoid a User Error. 2) Implemented the engine.isGATKLite() method. 2012-07-17 12:23:40 -04:00
Eric Banks d5b3a2eabf Merge branch 'master' of ssh://gsa2.broadinstitute.org/humgen/gsa-scr1/gsa-engineering/git/unstable 2012-07-17 00:32:53 -04:00
Eric Banks 0a89adbcdb Add utility decorators so that classes can tell you which package source they come from if they want to (suggested by Khalid). Using those decorators, we can easily pull out the BQSR updateDataForPileupElement() method into a standard RecalibrationEngine and an AdvancedRecalibrationEngine and use the protected one (AdvancedRE) if available (otherwise, the public one). 2012-07-16 15:34:50 -04:00
Joel Thibault 6c6a324583 Loosen a restriction on isOriginalRead()
* no longer needs to satisfy ReadAndIntervalOverlap.OVERLAP_CONTAINED
2012-07-16 14:07:10 -04:00
Eric Banks d7bf74fb7e Updating default value for -mindel to the one used by Khalid in the pipeline and me in my tests. 2012-07-10 02:04:26 -04:00
Mauricio Carneiro 6c17c50fa2 Updates to ReduceReads
* Added optional parameter to not hard clip on the interval border
   * Made not clipping the default behavior (hence integration tests changed)
   * Updated integration tests.
2012-07-09 13:46:51 -04:00
Mauricio Carneiro 12d1c594df Moving ReduceReads into protected 2012-06-25 17:01:33 -04:00
David Roazen 9c6bccfd8b build system overhaul
* Added support for a protected directory whose contents are only made public in binary form

* Simplified and reorganized build.xml to improve readability and maintainability

* build.xml now autodetects most build properties:
    -Includes private/protected if they exist
    -No more STING_BUILD_TYPE or specialized targets for public-only, etc.

* Build targets have changed! There are now two main build options:

"ant"       build everything (GATK and Queue)
"ant gatk"  build just the GATK

It was too hard to build everything before -- now it is the default.

* To run tests with debugging, use -Dtest.debug=true -Dtest.debug.port=XXXX on the command line.
  Much better than the old comment/uncomment method!
2012-05-17 15:16:29 -04:00