2cf21317f9
Create package that contains just what Picard needs.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2282 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 21:22:07 +00:00
a3e88c0b1c
Cleanup results of bad merge.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2281 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 19:30:49 +00:00
10be5a5de9
Move some files around to reflect our growing help infrastructure.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2280 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 19:23:12 +00:00
16ef500139
Tweak the build.sysclasspath option to force the system classpath to always be appended to additional jars added to the classpath by us. These seemed to be set differently depending on the platform or distribution before.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2279 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 19:19:29 +00:00
c9e385f541
Add TileCovariate to GenomeAnalysisTK package
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2277 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 16:39:59 +00:00
1d5b9883db
Added --solid_recal_mode argument to experiment with different ways of dealing with solid reference bias. Currently the default option is DO_NOTHING which means use the same behavior as the old recalibrator. Eventually the new methods in RecalDataManager will be moved over to a SolidUtils class. Added transition and transversion methods to BaseUtils that work like simpleComplement, used with the color space in my solid methods. Also, initial check-in of HomopolymerCovariate.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2276 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 14:26:27 +00:00
2632cb6b58
minor improvements to snp selector
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2275 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 03:37:14 +00:00
8f461d3c40
Critical bug fix for VariantEval dbSNP calculations. Moved the system over to the new improved ROD iterators, resulting in dbSNP rates jumping 5% or so, due to masking of true SNPs by preceding indels.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2274 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 03:36:38 +00:00
8089aa3c50
Adding support to override the help text.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2273 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-07 00:16:26 +00:00
c0528cd88e
Updated the CallsetConcordance classes to use new VCF Variation code... and uncovered a whole bunch of VCF bugs in the process. I'm not convinced that I got them all, so I'll unit test like crazy when the refactoring is done.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2272 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-06 11:43:40 +00:00
b6f8e33f4c
Stage 2 of Variation refactoring:
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VCFRecord now implements Variation, VCFGenotypeRecord now implements Genotype.
Because of this change, RodVCF is now just a wrapper around the VCFRecord and does nothing else. Also, one can call toVariation on the VCFGenotypeRecord and it returns the VCFRecord.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2271 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-06 06:48:03 +00:00
3b440e0dbc
Add a taglet to allow users to override the display name in command-line help.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2270 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-06 04:12:10 +00:00
08f2214f14
Stage 1 of massive Variation/Genotype refactoring.
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This stage consists only of the code originating in the Genotyper and flowing through to the genotype writers. I haven't finished refactoring the writers and haven't even touched the readers at all.
The major changes here are that
1. Variations which are BackedByGenotypes are now correctly associated with those Genotypes
2. Genotypes which have an associated Variation can actually be associated with it (and then return it when toVariation() is called).
The only integration tests which need to be updated are MSG-related (because the refactoring now made it easy for me to prevent MSG from emitting tri-allelic sites).
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2269 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-06 03:12:41 +00:00
b817db0962
Syzygy has a default LOD score of 0.91 on bases with no coverage, this is problematic. Set the minimum lod threshold to 1 because I just don't want to see that codswallop.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2268 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 23:29:14 +00:00
b04de77952
First pass at a reorganized walker info display. Groups walkers by package
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and displays walker data extracted from the JavaDoc. Needs a bit of help,
both in content and flexibility of package naming.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2267 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 23:24:29 +00:00
07b88621c5
Improved RankSum calculations and RankSum annotation. Much more meaningful
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2266 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 22:16:40 +00:00
0753315156
updates to the python snp selector -- now sorts info fields and we stop printing unnecessary debugging info in vcf2table
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2265 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 22:16:02 +00:00
0f89a38473
forgot to commit this earlier
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2264 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 22:10:16 +00:00
4c147329a9
Turn javadoc comments for packages and classes into key/value pairs in a properties file. Embed the properties file
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in GenomeAnalysisTK.jar. Still no support for actually displaying the archived javadoc. Also change the approach
to providing package javadocs: retired the deprecated package.html file in favor of Java1.5-style package-info.java.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2263 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 20:08:41 +00:00
c1263e841c
stop printing the debug info -- hurr
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Also it turns out that sometimes there can be a call with zero total non-I/non-D bases -- so add one to numerator and denominator to prevent divide by zero error
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2262 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 16:17:38 +00:00
0c2d6d7e41
A brute-force script to convert Syzygy lod-score calls files into a proper VCF -- with some useful annotations.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2261 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 16:07:06 +00:00
1e8dcc30da
-dbSNP rod should not implement VariantBackedByGenotype since dbsnp records have no genotype data
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-added code to cache the allele list so it didn't need to get recomputed each time it was requested.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2260 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 14:56:48 +00:00
855face681
Histogram of covariate values now goes from 0 to max value which makes it look nicer in most cases.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2259 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 14:44:03 +00:00
985daec76e
Fixed problem with integer overflow in R scripts.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2258 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 14:24:49 +00:00
2508deca37
Prevented data points with fewer than N observations from going off the edge of the plots
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2257 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 13:55:43 +00:00
58937bf9ba
You can now use the -exp flag to tell the Genotyper to include experimental annotations when it calls out to VariantAnnotator.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2256 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 04:45:05 +00:00
b05e73a914
Finished implementation of the Wilcoxon Rank Sum Test thanks to Tim Fennell (calculating the normal approximation) and Nick Patterson (dithering to break tie bands).
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2255 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 04:04:39 +00:00
861221d046
- Moved various header line printing into a single method
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- Fixed output for coverage above min depth
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2254 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-04 02:15:43 +00:00
2c7cb912f0
Bug fixes for mixed none/valued attributes. also now assigns fake float values for display, if requested, for covariates using the -plottable flag
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2253 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 23:52:35 +00:00
3eea1ece7a
Adding the ruby directory, and a simple script to restart Bamboo
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2251 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 22:48:48 +00:00
ac3895c218
Update the location of the DepthOfCoverage tool in the packaging system.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2250 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 19:11:53 +00:00
aef4be5610
Moved CoarseCoverageWalker to core and packaged both coverage walkers in coverage/
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2249 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 17:53:36 +00:00
df4e001a07
Renamed to more accurately describe its function.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2248 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 17:34:49 +00:00
c2017cc91b
PrintCoverageWalker functionality moved to DepthOfCoverageWalker. Added integration tests.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2247 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 17:23:59 +00:00
608fa4cc3a
Update packaging system to produce multiple jars if asked nicely.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2246 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 17:11:12 +00:00
01cf5cc741
1. Merged CoverageHistogram into DepthOfCoverageWalker
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2. Fixed bug in histogram calculation for small intervals
3. Better output in DoCWalker
4. Comments added to code
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2245 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 17:01:53 +00:00
44b9f60735
PercentOfBasesCovered functionality moved to DepthOfCoverageWalker. Added integration tests.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2244 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 16:11:09 +00:00
126d1eca35
Move to core (qc/)
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2243 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 15:45:58 +00:00
9da5cc25ad
More archiving (with permission from Andrey) plus a move to core.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2242 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 15:40:27 +00:00
b3bdcd0e60
make sure we close the error log stream in CommandLineProgram if it's opened; unit tests and clean-up for BasicVariation
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2241 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 06:59:27 +00:00
d27d56ea0c
adding the option to not halt after a test failure; it will still report failure at the end. This makes sense for Bamboo so we know all the tests that fail, not just the first. It is also useful for checking what tests are affected by a change.
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You can tell ant not to halt with: 'ant -Dhalt=no' (yes is the default)
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2240 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 06:19:39 +00:00
a88202c3f6
Refactored DoCWalker to output in a more helpful and usable style. It now outputs in tabular format with 2 different sections: per locus and then per interval.
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I am now at a point where I can merge the functionality from other coverage walkers into this one.
Thanks to Andrew for input.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2239 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 05:28:21 +00:00
d7e4cd4c82
Moving some useful and stable walkers to core:
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- ClipReads
- PrintRODs (generalized to print all RODs that are Variations)
- FixBAMSortOrderTag (added documentation to walker so that people know what it does and why)
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2238 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 03:00:45 +00:00
2460f2a789
minor update to build.xml for CG utilities. Hopefully bamboo will be back online
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2237 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-03 00:06:02 +00:00
0b6b92bf5b
Fix (hopefully) the rest of the problems with the build.xml svn merge.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2236 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-02 23:53:31 +00:00
f41965a73e
Fixed incompatiblity in variable name between my script and the new elements merged into my script.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2235 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-02 23:40:50 +00:00
357abc9e89
Update build.xml to make it oneoffprojects-aware, and do some misc formatting cleanup and moves.
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Here goes nothing.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2234 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-02 23:27:45 +00:00
46f3d3e39b
Added comments to AnalyzeCovariates and R scripts. R script prevents residuals from going off the edge of the plot. Added skeleton code to the recalibration walkers showing how we plan to handle SOLID reference inserting behavior.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2233 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-02 23:15:52 +00:00
451a20ed55
commenting out some broken integration tests, to be uncommented if needed.
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2232 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-02 23:13:24 +00:00
dbb8b86ed1
Minor updates to correctly handle emitting FN calls
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git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2231 348d0f76-0448-11de-a6fe-93d51630548a
2009-12-02 22:53:17 +00:00
alecw
hanna
rpoplin
depristo
ebanks
chartl
aaron