Commit Graph

14008 Commits (19bbe45cbc3960bcb70b6bfb74bdb4e73e762851)

Author SHA1 Message Date
Geraldine Van der Auwera 19bbe45cbc Updated licenses for 2015 2015-08-06 15:23:11 -04:00
Geraldine Van der Auwera 9554e06952 Merge pull request #1119 from broadinstitute/db_diff_objects
Moved DiffObjects from test to main (issue #1116)
2015-08-06 14:43:39 -04:00
David Benjamin ddb01058d3 moved DiffObjects 2015-08-05 21:19:02 -04:00
David Benjamin 893c09b6e0 Merge pull request #1107 from broadinstitute/db_issue_1052
UnifiedGenotypingEngine queries VariantContext for model if not given
2015-08-05 21:16:29 -04:00
David Benjamin 5fcc3788bd UnifiedGenotypingEngine queries VariantContext for model if not given 2015-08-05 15:30:37 -04:00
Eric Banks c34d8174fc Merge pull request #1114 from broadinstitute/eb_fix_IR_secondary_mates
Patch for the incorrect "fixing" of mates when supplementary alignments are present
2015-08-05 14:13:24 -04:00
Eric Banks df033f674d Patch for the incorrect "fixing" of mates when supplementary alignments are present.
Note that this patch involves ignoring supplementary alignments.  Ideally we would want
to fix their mates properly but that would require a major refactoring of this soon-to-be
deprecated tool.
2015-08-05 12:55:39 -04:00
Valentin Ruano Rubio f73871c865 Merge pull request #1098 from broadinstitute/vrr_rcm_is_active_calculateGenotypes
Faster implementation of the active state profile value calculation w…
2015-07-30 10:57:33 -04:00
vruano 604fb7aaf8 Faster implementation of the active state profile value calculation when running HC with a single sample.
Find out about a dev-bug and added TODOs (reported in #1096).

Addresses issue #1095.

Conflicts:
	protected/gatk-tools-protected/src/main/java/org/broadinstitute/gatk/tools/walkers/haplotypecaller/HaplotypeCaller.java
2015-07-30 10:56:05 -04:00
Geraldine Van der Auwera 9819624801 Merge pull request #1105 from broadinstitute/gvda_typo_fixes_1087_1042
Fixed typos and made some argument docs improvements
2015-07-29 23:37:00 -04:00
Geraldine Van der Auwera 875c7ffa1a Fixed typos and made some argument docs improvements 2015-07-29 23:06:19 -04:00
Valentin Ruano Rubio bb4c9fa1d3 Merge pull request #1099 from broadinstitute/vrr_magic_numbers
Extracted some constant expressions involved HC variation discovery a…
2015-07-29 13:38:23 -04:00
vruano 02c7876c72 Extracted some constant expressions involved HC variation discovery and genotyping.
Addreses issue #1092.
2015-07-29 11:58:13 -04:00
Geraldine Van der Auwera ac86b22662 Merge pull request #1101 from broadinstitute/ms_remove_KBest_unique
Removes unique(int maxSize) from KBestHaplotypeFinder
2015-07-28 17:27:48 -04:00
meganshand 4d4de27ba3 Removes unique(int maxSize) from KBestHaplotypeFinder 2015-07-28 15:54:21 -04:00
Louis Bergelson 9d9827f176 Merge pull request #1031 from broadinstitute/lb_update_for_java8
Updated gatk so it compiles with java 8
2015-07-28 11:09:19 -04:00
Valentin Ruano Rubio 3a3ff558c4 Merge pull request #1085 from broadinstitute/vrr_path_builder
ReferenceConfidenceModel likelihood calculation in non…
2015-07-28 10:48:03 -04:00
Geraldine Van der Auwera 43a37fc746 Merge pull request #1075 from broadinstitute/ldg_bamoutDocs
Add info about multiple input samples (as relevant for M2)
2015-07-27 16:56:36 -04:00
Geraldine Van der Auwera 5939b4c100 Merge pull request #1073 from broadinstitute/ldg_SV-MVtestNameFix
Fix logging name on SelectVariantsIntegrationTest::testInvertMendelia…
2015-07-27 16:54:59 -04:00
vruano 8f6daf70db Refactoring of ReferenceConfidenceModel likelihood calculation in non variant sites
Changed a division by -10.0 to a multiplication by -.1 in QualUtils (typically multiplication is faster than division).

Addresses performance issue #1081.
2015-07-26 08:33:46 -04:00
Valentin Ruano Rubio d4423d8303 Merge pull request #1079 from broadinstitute/vrr_path_builder
PathBuilder for linear time creation of Graph paths (quadratic currently).
2015-07-24 09:36:06 -04:00
vruano 047aea9707 Address performance issue #1077 2015-07-23 13:44:10 -04:00
Lee Lichtenstein c98be3dbd6 Merge pull request #1076 from broadinstitute/dr_move_swapext_to_utils
Move swapExt() methods to QScriptUtils, have versions in QScript class call into the util versions
2015-07-23 12:07:45 -04:00
David Roazen 5fd3d2be76 Move swapExt() methods to QScriptUtils, have versions in QScript class call into the util versions 2015-07-23 10:23:55 -04:00
Laura Gauthier 4fefedfb0b Fix logging name on SelectVariantsIntegrationTest::testInvertMendelianViolationSelection() 2015-07-23 09:48:15 -04:00
Laura Gauthier 85b340caed Add info about multiple input samples (as relevant for M2)
Also generalize references to the tool/caller since this code is now shared by HC and M2
2015-07-23 09:46:10 -04:00
Valentin Ruano Rubio 66cf22b28f Merge pull request #1069 from broadinstitute/vrr_ad_genotype_gvcfs_bugfix
Fix AD propagation when subsetting alleles in non-diploid GenotypeGVCF.
2015-07-22 18:53:43 -04:00
vruano 315e193e51 Fix AD propagation when subsetting alleles in non-diploid GenotypeGVCF.
Addresses issue #913.

Also remove some commented out code and toxic debugging code that uses System.out/err.println.
2015-07-22 17:08:13 -04:00
Geraldine Van der Auwera 75081bee2b Merge pull request #1068 from broadinstitute/gvda_remove_beagle_walkers_971
Removed walkers for handling Beagle data
2015-07-22 15:47:19 -04:00
Geraldine Van der Auwera d89067c791 Merge pull request #1066 from broadinstitute/gvda_fix_TR_license_1065
Updated license text and fixed a couple of typos in doc block
2015-07-22 12:28:05 -04:00
Joseph White 3bd988825f Removed walkers for handling Beagle data
Added deprecation statements to DeprecatedToolChecks.java
    Removed integration test for Beagle walker
    Added URL for Beagle documentation
2015-07-21 18:36:08 -04:00
Geraldine Van der Auwera ca082bfb76 Updated license text and fixed a couple of typos in doc block 2015-07-21 17:55:48 -04:00
Eric Banks 178bf12b27 Merge pull request #1046 from broadinstitute/rhl_catvariants_sort
Fix for mis-sorted VCF files in CatVariants
2015-07-21 17:37:27 -04:00
Valentin Ruano Rubio 9360e1d293 Merge pull request #1059 from broadinstitute/vrr_true_false_list_removal
More efficient implementation of the indel read qualities recalculati…
2015-07-21 17:13:45 -04:00
vruano 82f1236633 More efficient implementation of the indel read qualities recalculation for the PCR error model.
Addresses #1054.
2015-07-21 14:25:11 -04:00
Geraldine Van der Auwera a4dde8f500 Merge pull request #1040 from broadinstitute/rhl_fasta_ref_maker
Merge contiguous intervals properly, closes #1035
2015-07-21 14:19:09 -04:00
Geraldine Van der Auwera da0c8c73fb Merge pull request #1055 from broadinstitute/ldg_TRAdocs
Updated TandemRepeatAnnotator docs
2015-07-21 14:16:20 -04:00
Geraldine Van der Auwera 4d9724df64 Merge pull request #1057 from broadinstitute/ldg_CGPvcfVerDoc
Clarify VCF version for supporting population alleles files
2015-07-21 14:15:07 -04:00
Laura Gauthier 8c18ead5e4 Clarify VCF version for supporting population alleles files
Clarify DeNovoPrior definition on PbyT
2015-07-20 13:42:57 -04:00
Laura Gauthier 7b29c55eb6 Updated TandemRepeatAnnotator docs 2015-07-17 17:26:56 -04:00
Valentin Ruano Rubio b296576505 Merge pull request #1050 from broadinstitute/vrr_true_false_list_removal
Removes a very inefficient way to iterate in ReferenceConfidenceModel…
2015-07-16 14:03:21 -04:00
vruano 7f74303f2b Removes a very inefficient way to iterate in ReferenceConfidenceModel.isReadInformativeAboutIndelsOfSize(...)
Addresses performance issue #1048.
2015-07-16 12:04:12 -04:00
Ron Levine 6e46b3696e Merge contiguous intervals properly 2015-07-14 15:23:37 -04:00
John Wallace 8fc631b7ae Fix for mis-sorted VCF files in CatVariants
When using CatVariants, VCF files were being sorted solely on the base
pair position of the first record, ignoring the chromosome.  This can
become problematic when merging files from different chromosomes,
espeically if you have multiple VCFs per chromosome.

As an example, assume the following 3 lines are all in separate files:
1       10
1       100
2       20

The merged VCF from CatVariants (without -assumeSorted) would read:
1       10
2       20
1       100

This has the potential to break tools that expect chromosomes to be
contiguous within a VCF file.

This commit changes the comparator from one of Pair<Integer, File> to
one of Pair<VariantContext, File>.  We construct a
VariantContextComparator from the provided reference, which will sort
the first record by chromosome and position properly.  Additionally, if
-assumeSorted is given, we simply use a null VariantContext as the first
record, which will all be equal (as all will be null)
2015-07-14 14:12:31 -04:00
ldgauthier 45a1d82305 Merge pull request #1041 from broadinstitute/ldg_ContEst
Ported latest (non-yet-public) ContEst into GATK-private
2015-07-10 19:42:03 -04:00
Laura Gauthier 1159cb3aa9 Ported latest (non-yet-public) ContEst into GATK; verified results against Firehose version
Change file paths to put ContEst stuff in cancer directory
2015-07-09 17:06:06 -04:00
Geraldine Van der Auwera 8ea4dcab8d Merge remote-tracking branch 'unstable/master' 2015-07-09 15:17:03 -04:00
kcibul 00526d4624 Merge pull request #1022 from broadinstitute/kc_m2_pon
update results of NA12878 using official ICE PON (same git hash for t…
2015-07-07 16:37:46 -04:00
kcibul e6dff9cc4e Merge pull request #1037 from broadinstitute/ldg_M2_contaminationAnalysis
Document contamination downsampling analysis
2015-07-07 16:36:52 -04:00
Geraldine Van der Auwera c109a953f8 Merge pull request #1029 from broadinstitute/rhl_vqslod_definition
Make VQSLOD definition accurate
2015-07-06 19:52:15 -04:00