As per Menachem's last commit, there's a minimally more efficient way of doing the MQ cap.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@4782 348d0f76-0448-11de-a6fe-93d51630548a
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@ -117,7 +117,10 @@ public class UnifiedGenotyperEngine {
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}
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}
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private void initialize(GenomeAnalysisEngine toolkit, UnifiedArgumentCollection UAC, Logger logger, PrintStream verboseWriter, VariantAnnotatorEngine engine, int numSamples) {
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private void initialize(GenomeAnalysisEngine toolkit, UnifiedArgumentCollection UAC, Logger logger, PrintStream verboseWriter, VariantAnnotatorEngine engine, int numSamples) {
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this.UAC = UAC;
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// note that, because we cap the base quality by the mapping quality, minMQ cannot be less than minBQ
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this.UAC = UAC.clone();
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this.UAC.MIN_MAPPING_QUALTY_SCORE = Math.max(UAC.MIN_MAPPING_QUALTY_SCORE, UAC.MIN_BASE_QUALTY_SCORE);
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this.logger = logger;
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this.logger = logger;
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this.verboseWriter = verboseWriter;
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this.verboseWriter = verboseWriter;
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this.annotationEngine = engine;
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this.annotationEngine = engine;
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@ -575,10 +578,8 @@ public class UnifiedGenotyperEngine {
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// all bits are set to false by default
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// all bits are set to false by default
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BitSet bitset = new BitSet(record.getReadLength());
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BitSet bitset = new BitSet(record.getReadLength());
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// if the mapping quality is too low or the mate is bad, we can just zero out the whole read and continue.
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// if the mapping quality is too low or the mate is bad, we can just zero out the whole read and continue
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// note that, because we cap the base quality by the mapping quality, if MQ < minBQ then we can filter this read.
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if ( record.getMappingQuality() < UAC.MIN_MAPPING_QUALTY_SCORE ||
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if ( record.getMappingQuality() < UAC.MIN_MAPPING_QUALTY_SCORE ||
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record.getMappingQuality() < UAC.MIN_BASE_QUALTY_SCORE ||
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(!UAC.USE_BADLY_MATED_READS && BadMateFilter.hasBadMate(record)) ) {
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(!UAC.USE_BADLY_MATED_READS && BadMateFilter.hasBadMate(record)) ) {
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return bitset;
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return bitset;
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}
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}
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