updated what constitutes removing entropy
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@1113 348d0f76-0448-11de-a6fe-93d51630548a
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@ -40,6 +40,9 @@ public class IntervalCleanerWalker extends LocusWindowWalker<Integer, Integer>
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public static final int MAX_QUAL = 99;
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// fraction of mismatches that need to no longer mismatch for a column to be considered cleaned
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private static final double MISMATCH_COLUMN_CLEANED_FRACTION = 0.75;
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private SAMFileWriter writer = null;
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private FileWriter indelOutput = null;
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private FileWriter statsOutput = null;
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@ -577,22 +580,25 @@ public class IntervalCleanerWalker extends LocusWindowWalker<Integer, Integer>
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for ( int i=0; i < reference.length(); i++ ) {
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if ( cleanedMismatchBases[i] == originalMismatchBases[i] )
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continue;
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if ( originalMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD )
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boolean didMismatch = false, stillMismatches = false;
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if ( originalMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD ) {
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didMismatch = true;
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originalMismatchColumns++;
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if ( cleanedMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD )
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if ( cleanedMismatchBases[i] > originalMismatchBases[i] * (1.0 - MISMATCH_COLUMN_CLEANED_FRACTION) ) {
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stillMismatches = true;
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cleanedMismatchColumns++;
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}
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} else if ( cleanedMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD ) {
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cleanedMismatchColumns++;
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}
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if ( snpsOutput != null ) {
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if ( originalMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD ) {
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if ( didMismatch ) {
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sb.append(reads.get(0).getRead().getReferenceName() + ":");
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sb.append(((int)leftmostIndex + i));
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if ( cleanedMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD )
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if ( stillMismatches )
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sb.append(" SAME_SNP\n");
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else
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sb.append(" NOT_SNP\n");
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//} else if ( cleanedMismatchBases[i] > totalBases[i] * MISMATCH_THRESHOLD ) {
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// sb.append(reads.get(0).getRead().getReferenceName() + ":");
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// sb.append(((int)leftmostIndex + i));
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// sb.append(" NEW_SNP\n");
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}
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}
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}
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