Change the truth VCF
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parent
aac5f55bbe
commit
d61b4c7e91
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@ -64,6 +64,9 @@ import java.util.Arrays;
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import java.util.List;
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public class VariantRecalibrationWalkersIntegrationTest extends WalkerTest {
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private static String TRAINING_VCF = comparisonDataLocation + "Validated/HapMap/3.3/sites_r27_nr.b37_fwd.vcf";
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private static String TRUTH_VCF = comparisonDataLocation + "Validated/Omni2.5_chip/Omni25_genotypes_2141_samples.b37.vcf";
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private static class VRTest {
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String inVCF;
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String aggregateVCF;
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@ -93,15 +96,15 @@ public class VariantRecalibrationWalkersIntegrationTest extends WalkerTest {
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}
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VRTest lowPass = new VRTest(validationDataLocation + "phase1.projectConsensus.chr20.raw.snps.vcf",
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"41e2d951a17de433fe378bb3d9ec75d4", // tranches
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"3fe87e69c6a613addb7eff5449e86aa1", // recal file
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"78b8f1934d77341df2f6a9fdbd30fa74"); // cut VCF
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"3ccb3aa81aebee74d32641105a64ea32", // tranches
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"1a87e9cdc66c53891eab61ab39ff2434", // recal file
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"217ee1523b6ddaf31f0eb0464b89bab6"); // cut VCF
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VRTest lowPassPlusExomes = new VRTest(validationDataLocation + "phase1.projectConsensus.chr20.raw.snps.vcf",
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validationDataLocation + "1kg_exomes_unfiltered.AFR.unfiltered.vcf",
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"ce4bfc6619147fe7ce1f8331bbeb86ce", // tranches
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"5a298554e9175961f63506c4e42ea78b", // recal file
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"f284c0cbb00407cc5273c6f1a871513e"); // cut VCF
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"be89401e09dd06817c43f152c789f854", // tranches
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"8ce11e7555cccb3f13ea34a9074aec00", // recal file
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"c09c2425744e8d914d69a2585dba0e97"); // cut VCF
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@DataProvider(name = "VRTest")
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public Object[][] createData1() {
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@ -119,8 +122,8 @@ public class VariantRecalibrationWalkersIntegrationTest extends WalkerTest {
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WalkerTest.WalkerTestSpec spec = new WalkerTest.WalkerTestSpec(
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"-R " + b37KGReference +
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" -resource:known=true,prior=10.0 " + GATKDataLocation + "dbsnp_132_b37.leftAligned.vcf" +
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" -resource:truth=true,training=true,prior=15.0 " + comparisonDataLocation + "Validated/HapMap/3.3/sites_r27_nr.b37_fwd.vcf" +
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" -resource:training=true,truth=true,prior=12.0 " + comparisonDataLocation + "Validated/Omni2.5_chip/Omni25_sites_1525_samples.b37.vcf" +
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" -resource:truth=true,training=true,prior=15.0 " + TRAINING_VCF +
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" -resource:training=true,truth=true,prior=12.0 " + TRUTH_VCF +
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" -T VariantRecalibrator" +
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" -input " + params.inVCF +
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" -L 20:1,000,000-40,000,000" +
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@ -159,8 +162,8 @@ public class VariantRecalibrationWalkersIntegrationTest extends WalkerTest {
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WalkerTest.WalkerTestSpec spec = new WalkerTest.WalkerTestSpec(
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"-R " + b37KGReference +
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" -resource:known=true,prior=10.0 " + GATKDataLocation + "dbsnp_132_b37.leftAligned.vcf" +
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" -resource:truth=true,training=true,prior=15.0 " + comparisonDataLocation + "Validated/HapMap/3.3/sites_r27_nr.b37_fwd.vcf" +
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" -resource:training=true,truth=true,prior=12.0 " + comparisonDataLocation + "Validated/Omni2.5_chip/Omni25_sites_1525_samples.b37.vcf" +
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" -resource:truth=true,training=true,prior=15.0 " + TRAINING_VCF +
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" -resource:training=true,truth=true,prior=12.0 " + TRUTH_VCF +
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" -T VariantRecalibrator" +
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" -input " + params.inVCF +
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" -aggregate " + params.aggregateVCF +
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@ -210,8 +213,8 @@ public class VariantRecalibrationWalkersIntegrationTest extends WalkerTest {
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WalkerTest.WalkerTestSpec spec = new WalkerTest.WalkerTestSpec(
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"-R " + b37KGReference +
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" -resource:known=true,prior=10.0 " + GATKDataLocation + "dbsnp_132_b37.leftAligned.vcf" +
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" -resource:truth=true,training=true,prior=15.0 " + comparisonDataLocation + "Validated/HapMap/3.3/sites_r27_nr.b37_fwd.vcf" +
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" -resource:training=true,truth=true,prior=12.0 " + comparisonDataLocation + "Validated/Omni2.5_chip/Omni25_sites_1525_samples.b37.vcf" +
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" -resource:truth=true,training=true,prior=15.0 " + TRAINING_VCF +
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" -resource:training=true,truth=true,prior=12.0 " + TRUTH_VCF +
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" -T VariantRecalibrator" +
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" -input " + params.inVCF +
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" -L 20:10,000,000-20,000,000" +
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