Actually hook up the new indel genotyper and merge analyses into DAG (aka "i forgot to add()")

git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@4149 348d0f76-0448-11de-a6fe-93d51630548a
This commit is contained in:
chartl 2010-08-27 18:00:50 +00:00
parent 9860db64a3
commit c6441b585a
1 changed files with 27 additions and 4 deletions

View File

@ -46,8 +46,19 @@ class fullCallingPipeline extends QScript {
var snpClusterWindow = 7
@Input(doc="dbSNP version",shortName="D")
var dbSNP: File = _
var dbSNP: File = _
@Input(doc="target titv for recalibration",shortName="titv",required=false)
var target_titv = 2.1
@Input(doc="downsampling coverage",shortname="dcov",required=false)
var downsampling_coverage = 200
@Input(doc="Number of jobs to scatter unifeid genotyper",shortname="snpScatter",required=false)
var num_snp_scatter_jobs = 50
@Input(doc="Number of jobs to scatter indel genotyper",shortname="indelScatter",required=false)
var num_indel_scatter_jobs = 5
trait CommandLineGATKArgs extends CommandLineGATK {
@ -128,11 +139,12 @@ class fullCallingPipeline extends QScript {
snps.rodBind :+= RodBind( "comp1KG_CEU", "VCF", qscript.comp1KGCEU )
}
snps.scatterCount = 50
snps.scatterCount = qscript.num_snp_scatter_jobs
// indel genotyper does one sample at a time
val indelCallFiles = List.empty[RodBind]
val indelGenotypers = List.empty[IndelGenotyperV2]
val loopNo = 0
val priority = ""
for ( bam <- bamFiles ) {
@ -141,6 +153,10 @@ class fullCallingPipeline extends QScript {
indel.out = swapExt(bam,".bam",".indels.vcf")
indel.downsample_to_coverage = Some(500)
indelCallFiles :+= new RodBind("v"+loopNo.toString, "VCF", indel.out)
indel.scatterCount = qscript.num_indel_scatter_jobs
indelGenotypers :+= indel
if ( loopNo == 0 ) {
priority = "v0"
} else {
@ -206,7 +222,7 @@ class fullCallingPipeline extends QScript {
recalibrate.rodBind :+= RodBind("input", "VCF", masker.out)
recalibrate.out = swapExt(masker.out,".vcf",".optimized.vcf")
// todo -- inputs for Ti/Tv expectation and other things -- command line
recalibrate.target_titv = 2.1
recalibrate.target_titv = qscript.target_titv
// 3.iii apply variant cuts to the clusters
@ -227,7 +243,14 @@ class fullCallingPipeline extends QScript {
eval.evalModule ++= List("CountFunctionalClasses", "CompOverlap", "CountVariants", "TiTvVariantEvaluator")
eval.out = new File(base+".eval")
add(snps,indels,annotated,masker,handFilter,clusters,recalibrate,cut,eval)
add(snps)
for ( igv2 <- indelGenotypers ) {
add(igv2)
}
add(mergeIndels,annotated,masker,handFilter,clusters,recalibrate,cut,eval)
}
}