Update stand_call_conf doc strings

This commit is contained in:
Ron Levine 2017-01-06 17:15:56 -05:00
parent e86da63d04
commit ab4a9fa64f
1 changed files with 7 additions and 3 deletions

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@ -101,9 +101,13 @@ public class GenotypeCalculationArgumentCollection implements Cloneable{
public double heterozygosityStandardDeviation = 0.01;
/**
* The minimum phred-scaled Qscore threshold to separate high confidence from low confidence calls. Only genotypes with
* confidence >= this threshold are emitted as called sites. A reasonable threshold is 30 for high-pass calling (this
* is the default).
* The minimum phred-scaled confidence threshold at which variants should be called. Only variant sites with QUAL equal
* or greater than this threshold will be called. Note that since version 3.7, we no longer differentiate high confidence
* from low confidence calls at the calling step. The default call confidence threshold is set low intentionally to achieve
* high sensitivity, which will allow false positive calls as a side effect. Be sure to perform some kind of filtering after
* calling to reduce the amount of false positives in your final callset. Note that when HaplotypeCaller is used in GVCF mode
* (using either -ERC GVCF or -ERC BP_RESOLUTION) the call threshold is automatically set to zero. Call confidence thresholding
* will then be performed in the subsequent GenotypeGVCFs command.
*/
@Argument(fullName = "standard_min_confidence_threshold_for_calling", shortName = "stand_call_conf", doc = "The minimum phred-scaled confidence threshold at which variants should be called", required = false)
public double STANDARD_CONFIDENCE_FOR_CALLING = 10.0;