Moved some more walkers to oneoffprojects and killed an old indel-related walker that isn't being used.
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2228 348d0f76-0448-11de-a6fe-93d51630548a
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package org.broadinstitute.sting.playground.gatk.walkers;
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package org.broadinstitute.sting.oneoffprojects.walkers;
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import net.sf.samtools.SAMRecord;
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import org.broadinstitute.sting.gatk.walkers.ReadWalker;
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package org.broadinstitute.sting.playground.gatk.walkers;
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package org.broadinstitute.sting.oneoffprojects.walkers;
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import net.sf.samtools.SAMRecord;
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import org.broadinstitute.sting.gatk.walkers.ReadWalker;
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package org.broadinstitute.sting.playground.gatk.walkers;
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package org.broadinstitute.sting.oneoffprojects.walkers;
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import org.broadinstitute.sting.gatk.walkers.ReadWalker;
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import org.broadinstitute.sting.utils.cmdLine.Argument;
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package org.broadinstitute.sting.playground.gatk.walkers;
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package org.broadinstitute.sting.oneoffprojects.walkers;
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import org.broadinstitute.sting.gatk.walkers.ReadWalker;
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import org.broadinstitute.sting.utils.cmdLine.Argument;
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package org.broadinstitute.sting.playground.gatk.walkers.indels;
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import net.sf.samtools.*;
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import org.broadinstitute.sting.gatk.refdata.*;
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import org.broadinstitute.sting.gatk.walkers.LocusWalker;
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import org.broadinstitute.sting.gatk.contexts.AlignmentContext;
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import org.broadinstitute.sting.gatk.contexts.ReferenceContext;
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import org.broadinstitute.sting.utils.*;
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import org.broadinstitute.sting.gatk.walkers.WalkerName;
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import java.util.*;
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@WalkerName("CoverageGapIntervals")
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public class CoverageGapIntervalWalker extends LocusWalker<Pair<GenomeLoc, Integer>, GenomeLoc> {
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private final int minReadsAtInterval = 10;
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public void initialize() {}
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public boolean filter(RefMetaDataTracker tracker, ReferenceContext ref, AlignmentContext context) {
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int goodReads = 0;
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List<SAMRecord> reads = context.getReads();
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for (int i = 0; i < reads.size(); i++ ) {
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if ( reads.get(i).getMappingQuality() > 0 )
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goodReads++;
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}
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return goodReads >= minReadsAtInterval;
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}
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public Pair<GenomeLoc, Integer> map(RefMetaDataTracker tracker, ReferenceContext ref, AlignmentContext context) {
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// find the probability that this locus has a statistically significant gap in coverage
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List<SAMRecord> reads = context.getReads();
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List<Integer> offsets = context.getOffsets();
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int totalXi = 0;
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for (int i = 0; i < reads.size(); i++ ) {
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SAMRecord read = reads.get(i);
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if ( read.getMappingQuality() == 0 )
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continue;
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int halfLength = read.getReadString().length() >> 1;
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int distanceFromMiddle = Math.abs(offsets.get(i) - halfLength);
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int quarterLength = halfLength >> 1;
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// Xi is < 0 if you are closer to the middle than the quartile
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// and is > 0 if further to the middle than quartile
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// We expect the total sum of Xi over an interval to be ~0
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int Xi = distanceFromMiddle - quarterLength;
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totalXi += Xi;
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}
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return new Pair<GenomeLoc, Integer>(context.getLocation(), totalXi);
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}
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public void onTraversalDone() {}
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public GenomeLoc reduceInit() {
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return null;
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}
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public GenomeLoc reduce(Pair<GenomeLoc, Integer> value, GenomeLoc sum) {
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if ( value.second > 1000 ) {
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if ( sum != null )
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sum = GenomeLocParser.setStop(sum,value.first.getStop());
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else
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sum = value.first;
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} else if ( sum != null ) {
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out.println(sum);
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sum = null;
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}
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return sum;
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}
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}
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