diff --git a/protected/java/src/org/broadinstitute/sting/gatk/walkers/indels/RealignerTargetCreator.java b/protected/java/src/org/broadinstitute/sting/gatk/walkers/indels/RealignerTargetCreator.java index dea17cd02..1ee04e317 100644 --- a/protected/java/src/org/broadinstitute/sting/gatk/walkers/indels/RealignerTargetCreator.java +++ b/protected/java/src/org/broadinstitute/sting/gatk/walkers/indels/RealignerTargetCreator.java @@ -91,9 +91,12 @@ import java.util.TreeSet; *
  • Running the realigner over those intervals (see the IndelRealigner tool)
  • * *

    - * An important note: the input BAM(s), reference, and known indel file(s) should be the same ones to be used for the IndelRealigner step. + * Important note 1: the input BAM(s), reference, and known indel file(s) should be the same ones to be used for the IndelRealigner step. *

    - * Another important note: because reads produced from the 454 technology inherently contain false indels, the realigner will not currently work with them + * Important note 2: when multiple potential indels are found by the tool in the same general region, the tool will choose the most likely + * one for realignment to the exclusion of the others. This is a known limitation of the tool. + *

    + * Important note 3: because reads produced from the 454 technology inherently contain false indels, the realigner will not currently work with them * (or with reads from similar technologies). This tool also ignores MQ0 reads and reads with consecutive indel operators in the CIGAR string. * *

    Input