diff --git a/public/java/src/org/broadinstitute/sting/gatk/walkers/coverage/DepthOfCoverageWalker.java b/public/java/src/org/broadinstitute/sting/gatk/walkers/coverage/DepthOfCoverageWalker.java
index 4537f06f8..3a18fe610 100644
--- a/public/java/src/org/broadinstitute/sting/gatk/walkers/coverage/DepthOfCoverageWalker.java
+++ b/public/java/src/org/broadinstitute/sting/gatk/walkers/coverage/DepthOfCoverageWalker.java
@@ -60,9 +60,6 @@ import java.util.*;
* and/or percentage of bases covered to or beyond a threshold.
* Additionally, reads and bases can be filtered by mapping or base quality score.
*
- * If any of the command-line arguments for this tool are not clear to you,
- * please email chartl at broadinstitute dot org and he will gladly explain them in more detail.
- *
*
Input
*
* One or more bam files (with proper headers) to be analyzed for coverage statistics
@@ -108,10 +105,19 @@ public class DepthOfCoverageWalker extends LocusWalker
*
- * If any of the command-line arguments for this tool are not clear to you,
- * please email chartl at broadinstitute dot org and he will gladly explain them in more detail.
- *
* Input
*
* Requires a VCF containing alleles to design amplicons towards, a VCF of variants to mask out of the amplicons, and an
@@ -96,20 +93,30 @@ import java.util.List;
*/
@Requires(value={DataSource.REFERENCE})
public class ValidationAmplicons extends RodWalker {
+ /**
+ * A Table-formatted file listing amplicon contig, start, stop, and a name for the amplicon (or probe)
+ */
@Input(fullName = "ProbeIntervals", doc="A collection of intervals in table format with optional names that represent the "+
"intervals surrounding the probe sites amplicons should be designed for", required=true)
RodBinding probeIntervals;
-
+ /**
+ * A VCF file containing the bi-allelic sites for validation. Filtered records will prompt a warning, and will be flagged as filtered in the output fastq.
+ */
@Input(fullName = "ValidateAlleles", doc="A VCF containing the sites and alleles you want to validate. Restricted to *BI-Allelic* sites", required=true)
RodBinding validateAlleles;
-
+ /**
+ * A VCF file containing variants to be masked. A mask variant overlapping a validation site will be ignored at the validation site.
+ */
@Input(fullName = "MaskAlleles", doc="A VCF containing the sites you want to MASK from the designed amplicon (e.g. by Ns or lower-cased bases)", required=true)
RodBinding maskAlleles;
-
@Argument(doc="Lower case SNPs rather than replacing with 'N'",fullName="lowerCaseSNPs",required=false)
boolean lowerCaseSNPs = false;
+ /**
+ * BWA single-end alignment is used as a primer specificity proxy. Low-complexity regions (that don't align back to themselves as a best hit) are lowercased.
+ * This changes the size of the k-mer used for alignment.
+ */
@Argument(doc="Size of the virtual primer to use for lower-casing regions with low specificity",fullName="virtualPrimerSize",required=false)
int virtualPrimerSize = 20;