Add dummy functionality (currently throws an error) to allow HC to include unmapped reads during assembly and calling
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@ -184,6 +184,16 @@ public class HaplotypeCaller extends ActiveRegionWalker<Integer, Integer> implem
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@Argument(fullName="downsampleRegion", shortName="dr", doc="coverage, per-sample, to downsample each active region to", required = false)
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protected int DOWNSAMPLE_PER_SAMPLE_PER_REGION = 1000;
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/**
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* If this flag is provided, the haplotype caller will include unmapped reads in the assembly and calling
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* when these reads occur in the region being analyzed. Typically, for paired end analyses, one pair of the
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* read can map, but if its pair is too divergent then it may be unmapped and placed next to its mate, taking
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* the mates contig and alignment start. If this flag is provided the haplotype caller will see such reads,
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* and may make use of them in assembly and calling, where possible.
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*/
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@Argument(fullName="includeUmappedReads", shortName="unmapped", doc="If provided, unmapped reads with chromosomal coordinates (i.e., those placed to their maps) will be included in the assembly and calling", required = false)
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protected boolean includeUnmappedReads = false;
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@Argument(fullName="useAllelesTrigger", shortName="allelesTrigger", doc = "If specified, use additional trigger on variants found in an external alleles file", required=false)
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protected boolean USE_ALLELES_TRIGGER = false;
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@ -354,11 +364,20 @@ public class HaplotypeCaller extends ActiveRegionWalker<Integer, Integer> implem
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// enable non primary and extended reads in the active region
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@Override
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public EnumSet<ActiveRegionReadState> desiredReadStates() {
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return EnumSet.of(
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ActiveRegionReadState.PRIMARY,
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ActiveRegionReadState.NONPRIMARY,
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ActiveRegionReadState.EXTENDED
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);
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if ( includeUnmappedReads ) {
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throw new UserException.BadArgumentValue("includeUmappedReads", "is not yet functional");
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// return EnumSet.of(
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// ActiveRegionReadState.PRIMARY,
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// ActiveRegionReadState.NONPRIMARY,
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// ActiveRegionReadState.EXTENDED,
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// ActiveRegionReadState.UNMAPPED
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// );
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} else
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return EnumSet.of(
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ActiveRegionReadState.PRIMARY,
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ActiveRegionReadState.NONPRIMARY,
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ActiveRegionReadState.EXTENDED
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);
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}
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@Override
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