updated some defaults

git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@1114 348d0f76-0448-11de-a6fe-93d51630548a
This commit is contained in:
ebanks 2009-06-26 19:28:05 +00:00
parent eb74b16e39
commit 3bacb3db03
1 changed files with 2 additions and 2 deletions

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@ -67,7 +67,7 @@ Optional Arguments:
--allow454Reads [don't filter out 454 reads (which inherently have false indels); default=false]
--mismatchFraction f [fraction of reads that need to mismatch for the position to be considered mismatching; default=0.25]
--mismatchFraction f [fraction of reads that need to mismatch for the position to be considered mismatching; default=0.15]
Note that this fraction should be adjusted based on your particular data set. For DEEP coverage and/or
when looking for indels with low allele frequency, this number should be smaller.
@ -106,7 +106,7 @@ This term is equivalent to "significance" - i.e. is the improvement significant
Note that this number should be adjusted based on your particular data set. For LOW coverage and/or
when looking for indels with low allele frequency, this number should be smaller.
--EntropyThreshold f [percentage of mismatching base quality scores at a position to be considered having high entropy; default=0.25]
--EntropyThreshold f [percentage of mismatching base quality scores at a position to be considered having high entropy; default=0.15]
This is similar to the argument in the MismatchIntervals method. The point here is that the realigner
will only proceed with the realignment (even above the given threshold) if it minimizes entropy among
the reads (and doesn't simply push the mismatch column to another position). This parameter is just