updated some defaults
git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@1114 348d0f76-0448-11de-a6fe-93d51630548a
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@ -67,7 +67,7 @@ Optional Arguments:
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--allow454Reads [don't filter out 454 reads (which inherently have false indels); default=false]
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--mismatchFraction f [fraction of reads that need to mismatch for the position to be considered mismatching; default=0.25]
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--mismatchFraction f [fraction of reads that need to mismatch for the position to be considered mismatching; default=0.15]
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Note that this fraction should be adjusted based on your particular data set. For DEEP coverage and/or
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when looking for indels with low allele frequency, this number should be smaller.
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@ -106,7 +106,7 @@ This term is equivalent to "significance" - i.e. is the improvement significant
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Note that this number should be adjusted based on your particular data set. For LOW coverage and/or
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when looking for indels with low allele frequency, this number should be smaller.
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--EntropyThreshold f [percentage of mismatching base quality scores at a position to be considered having high entropy; default=0.25]
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--EntropyThreshold f [percentage of mismatching base quality scores at a position to be considered having high entropy; default=0.15]
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This is similar to the argument in the MismatchIntervals method. The point here is that the realigner
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will only proceed with the realignment (even above the given threshold) if it minimizes entropy among
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the reads (and doesn't simply push the mismatch column to another position). This parameter is just
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