-VCF writer now checks whether the allele frequency has been set before trying to write it out.
-Renamed methods to be more consistent. git-svn-id: file:///humgen/gsa-scr1/gsa-engineering/svn_contents/trunk@2214 348d0f76-0448-11de-a6fe-93d51630548a
This commit is contained in:
parent
6231637615
commit
2838629724
|
|
@ -78,7 +78,7 @@ public abstract class EMGenotypeCalculationModel extends GenotypeCalculationMode
|
||||||
|
|
||||||
((SLODBacked)locusdata).setSLOD(strandScore);
|
((SLODBacked)locusdata).setSLOD(strandScore);
|
||||||
}
|
}
|
||||||
locusdata.setAlleleFrequency(overall.getMAF());
|
locusdata.setNonRefAlleleFrequency(overall.getMAF());
|
||||||
}
|
}
|
||||||
return new Pair<List<Genotype>, GenotypeLocusData>(genotypeCallsFromGenotypeLikelihoods(overall, ref, contexts), locusdata);
|
return new Pair<List<Genotype>, GenotypeLocusData>(genotypeCallsFromGenotypeLikelihoods(overall, ref, contexts), locusdata);
|
||||||
}
|
}
|
||||||
|
|
|
||||||
|
|
@ -323,7 +323,7 @@ public abstract class JointEstimateGenotypeCalculationModel extends GenotypeCalc
|
||||||
GenotypeLocusData locusdata = GenotypeWriterFactory.createSupportedGenotypeLocusData(OUTPUT_FORMAT, ref, loc, VARIANT_TYPE.SNP);
|
GenotypeLocusData locusdata = GenotypeWriterFactory.createSupportedGenotypeLocusData(OUTPUT_FORMAT, ref, loc, VARIANT_TYPE.SNP);
|
||||||
if ( locusdata != null ) {
|
if ( locusdata != null ) {
|
||||||
locusdata.addAlternateAllele(bestAlternateAllele.toString());
|
locusdata.addAlternateAllele(bestAlternateAllele.toString());
|
||||||
locusdata.setAlleleFrequency((double)bestAFguess / (double)(frequencyEstimationPoints-1));
|
locusdata.setNonRefAlleleFrequency((double)bestAFguess / (double)(frequencyEstimationPoints-1));
|
||||||
if ( locusdata instanceof ConfidenceBacked ) {
|
if ( locusdata instanceof ConfidenceBacked ) {
|
||||||
((ConfidenceBacked)locusdata).setConfidence(phredScaledConfidence);
|
((ConfidenceBacked)locusdata).setConfidence(phredScaledConfidence);
|
||||||
}
|
}
|
||||||
|
|
|
||||||
|
|
@ -16,10 +16,16 @@ public interface GenotypeLocusData extends Variation {
|
||||||
*/
|
*/
|
||||||
public void addAlternateAllele(String alt);
|
public void addAlternateAllele(String alt);
|
||||||
|
|
||||||
|
/**
|
||||||
|
*
|
||||||
|
* @return true if the allele frequency has been set
|
||||||
|
*/
|
||||||
|
public boolean hasNonRefAlleleFrequency();
|
||||||
|
|
||||||
/**
|
/**
|
||||||
*
|
*
|
||||||
* @param frequency the allele frequency for this genotype
|
* @param frequency the allele frequency for this genotype
|
||||||
*/
|
*/
|
||||||
public void setAlleleFrequency(double frequency);
|
public void setNonRefAlleleFrequency(double frequency);
|
||||||
|
|
||||||
}
|
}
|
||||||
|
|
@ -21,7 +21,7 @@ public class VCFGenotypeLocusData implements GenotypeLocusData, ConfidenceBacked
|
||||||
private Double mSLOD = null;
|
private Double mSLOD = null;
|
||||||
|
|
||||||
// the allele frequency field
|
// the allele frequency field
|
||||||
private double mAlleleFrequency = 0.0;
|
private double mAlleleFrequency = -1.0;
|
||||||
|
|
||||||
// the location
|
// the location
|
||||||
private GenomeLoc mLoc;
|
private GenomeLoc mLoc;
|
||||||
|
|
@ -97,6 +97,10 @@ public class VCFGenotypeLocusData implements GenotypeLocusData, ConfidenceBacked
|
||||||
return mType;
|
return mType;
|
||||||
}
|
}
|
||||||
|
|
||||||
|
public boolean hasNonRefAlleleFrequency() {
|
||||||
|
return mAlleleFrequency >= 0.0;
|
||||||
|
}
|
||||||
|
|
||||||
public double getNonRefAlleleFrequency() {
|
public double getNonRefAlleleFrequency() {
|
||||||
return mAlleleFrequency;
|
return mAlleleFrequency;
|
||||||
}
|
}
|
||||||
|
|
@ -171,7 +175,7 @@ public class VCFGenotypeLocusData implements GenotypeLocusData, ConfidenceBacked
|
||||||
*
|
*
|
||||||
* @param frequency the allele frequency for this genotype
|
* @param frequency the allele frequency for this genotype
|
||||||
*/
|
*/
|
||||||
public void setAlleleFrequency(double frequency) {
|
public void setNonRefAlleleFrequency(double frequency) {
|
||||||
mAlleleFrequency = frequency;
|
mAlleleFrequency = frequency;
|
||||||
}
|
}
|
||||||
|
|
||||||
|
|
|
||||||
|
|
@ -190,6 +190,7 @@ public class VCFGenotypeWriterAdapter implements GenotypeWriter {
|
||||||
if ( locusdata != null ) {
|
if ( locusdata != null ) {
|
||||||
if ( locusdata.getSLOD() != null )
|
if ( locusdata.getSLOD() != null )
|
||||||
infoFields.put("SB", String.format("%.2f", locusdata.getSLOD()));
|
infoFields.put("SB", String.format("%.2f", locusdata.getSLOD()));
|
||||||
|
if ( locusdata.hasNonRefAlleleFrequency() )
|
||||||
infoFields.put("AF", String.format("%.2f", locusdata.getNonRefAlleleFrequency()));
|
infoFields.put("AF", String.format("%.2f", locusdata.getNonRefAlleleFrequency()));
|
||||||
Map<String, String> otherFields = locusdata.getFields();
|
Map<String, String> otherFields = locusdata.getFields();
|
||||||
if ( otherFields != null ) {
|
if ( otherFields != null ) {
|
||||||
|
|
|
||||||
Loading…
Reference in New Issue